Pacemaker neurons and the development of nociception

Neuroscientist

Volumn 20, Issue 3, 2014, Pages 197-202

  Baccei, Mark L ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

neonate; rhythmic burst firing; spinal cord; superficial dorsal horn

Indexed keywords

POTASSIUM CHANNEL; CALCIUM; SUCCINATE DEHYDROGENASE;

ACTION POTENTIAL; ANIMAL CELL; BRAIN DEVELOPMENT; CELL MATURATION; INTERNEURON; NEWBORN; NOCICEPTION; NONHUMAN; PACEMAKER NERVE CELL; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; REVIEW; SENSORIMOTOR INTEGRATION; SIGNAL PROCESSING; SPINAL CORD DORSAL HORN; ANIMAL; BIOLOGICAL RHYTHM; GROWTH, DEVELOPMENT AND AGING; NERVE CELL; PHYSIOLOGY; SPINAL CORD; ANTERIOR COMMISSURE; CALCIUM TRANSPORT; CENTRAL NERVOUS SYSTEM; HUMAN; MEMBRANE CONDUCTANCE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MEMBRANE STEADY POTENTIAL; NERVE FIBER; NERVOUS SYSTEM FUNCTION; NEWBORN PERIOD; PACEMAKER NEURON; POSTNATAL DEVELOPMENT; SINUS NODE; SYNAPTIC TRANSMISSION;

ANIMALS; BIOLOGICAL CLOCKS; NEURONS; NOCICEPTION; SPINAL CORD; SPINAL CORD DORSAL HORN;

EID: 84900864201     PISSN: 10738584     EISSN: 10894098     Source Type: Journal    
DOI: 10.1177/1073858414521499     Document Type: Review

References (34)

1. Aizenman CD, Munoz-Elias G, Cline HT. Visually driven modulation of glutamatergic synaptic transmission is mediated by the regulation of intracellular polyamines. Neuron. 2002 ; 34: 623-34
2. Bal T, McCormick DA. Synchronized oscillations in the inferior olive are controlled by the hyperpolarization-activated cation current I(h). J Neurophysiol. 1997 ; 77: 3145-56
3. Beggs S, Torsney C, Drew LJ, Fitzgerald M.. The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity-dependent process. Eur J Neurosci. 2002 ; 16: 1249-58
4. Bicknell HR, Beal JA. Axonal and dendritic development of substantia gelatinosa neurons in the lumbosacral spinal cord of the rat. J Comp Neurol. 1984 ; 226: 508-22
5. Blankenship AG, Feller MB. Mechanisms underlying spontaneous patterned activity in developing neural circuits. Nat Rev Neurosci. 2010 ; 11: 18-29
6. Brocard F, Shevtsova NA, Bouhadfane M, Tazerart S, Heinemann U, Rybak IA. Activity-dependent changes in extracellular Ca2+ and K+ reveal pacemakers in the spinal locomotor-related network. Neuron. 2013 ; 77: 1047-54
7. Cueni L, Canepari M, Lujan R, Emmenegger Y, Watanabe M, Bond CT. T-type Ca2+ channels, SK2 channels and SERCAs gate sleep-related oscillations in thalamic dendrites. Nat Neurosci. 2008 ; 11: 683-92
8. Del Negro CA, Koshiya N, Butera RJ, Smith JC. Persistent sodium current, membrane properties and bursting behavior of pre-botzinger complex inspiratory neurons in vitro. J Neurophysiol. 2002 ; 88: 2242-50
9. Derjean D, Bertrand S, Le Masson G, Landry M, Morisset V, Nagy F. Dynamic balance of metabotropic inputs causes dorsal horn neurons to switch functional states. Nat Neurosci. 2003 ; 6: 274-81
10. Eide AL, Glover J, Kjaerulff O, Kiehn O. Characterization of commissural interneurons in the lumbar region of the neonatal rat spinal cord. J Comp Neurol. 1999 ; 403: 332-45
11. Hibino H, Inanobe A, Furutani K, Murakami S, Findlay I, Kurachi Y. Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev.. 2010 ; 90: 291-366
12. Huguenard JR. Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol. 1996 ; 58: 329-48
13. Jovanovic K, Pastor AM, O'Donovan MJ. The use of PRV-Bartha to define premotor inputs to lumbar motoneurons in the neonatal spinal cord of the mouse. PLoS One. 2010 ; 5: e11743
14. Koch SC, Fitzgerald M. Activity-dependent development of tactile and nociceptive spinal cord circuits. Ann N Y Acad Sci. 2013 ; 1279: 97-102
15. Li J, Baccei ML. Pacemaker neurons within newborn spinal pain circuits. J Neurosci. 2011 ; 31: 9010-22
16. Li J, Baccei ML. Developmental regulation of membrane excitability in rat spinal lamina I projection neurons. J Neurophysiol. 2012 ; 107: 2604-14
17. Li J, Blankenship ML, Baccei ML. Inward-rectifying potassium (Kir) channels regulate pacemaker activity in spinal nociceptive circuits during early life. J Neurosci. 2013 ; 33: 3352-62
18. Li P, Zhuo M. Silent glutamatergic synapses and nociception in mammalian spinal cord. Nature. 1998 ; 393: 695-8
19. McLaughlin T, Torborg CL, Feller MB, O'Leary DD. Retinotopic map refinement requires spontaneous retinal waves during a brief critical period of development. Neuron. 2003 ; 40: 1147-60
20. Park JS, Nakatsuka T, Nagata K, Higashi H, Yoshimura M. Reorganization of the primary afferent termination in the rat spinal dorsal horn during post-natal development. Brain Res Dev Brain Res. 1999 ; 113: 29-36
21. Petersson P, Waldenstrom A, Fahraeus C, Schouenborg J. Spontaneous muscle twitches during sleep guide spinal self-organization. Nature. 2003 ; 424: 72-5
22. Prescott SA, De Koninck Y. Integration time in a subset of spinal lamina I neurons is lengthened by sodium and calcium currents acting synergistically to prolong subthreshold depolarization. J Neurosci. 2005 ; 25: 4743-54
23. Romani A. Regulation of magnesium homeostasis and transport in mammalian cells. Arch Biochem Biophys. 2007 ; 458: 90-102
24. Ryu PD, Randic M. Low- and high-voltage-activated calcium currents in rat spinal dorsal horn neurons. J Neurophysiol. 1990 ; 63: 273-85
25. Spike RC, Puskar Z, Andrew D, Todd AJ. A quantitative and morphological study of projection neurons in lamina I of the rat lumbar spinal cord. Eur J Neurosci. 2003 ; 18: 2433-48
26. Szucs P, Luz LL, Pinho R, Aguiar P, Antal Z, Tiong SY. Axon diversity of lamina I local-circuit neurons in the lumbar spinal cord. J Comp Neurol. 2013 ; 521: 2719-41
27. Szucs P, Pinto V, Safronov BV. Advanced technique of infrared LED imaging of unstained cells and intracellular structures in isolated spinal cord, brainstem, ganglia and cerebellum. J Neurosci Methods. 2009 ; 177: 369-80
28. Tazerart S, Vinay L, Brocard F. The persistent sodium current generates pacemaker activities in the central pattern generator for locomotion and regulates the locomotor rhythm. J Neurosci. 2008 ; 28: 8577-89
29. Thoby-Brisson M, Karlen M, Wu N, Charnay P, Champagnat J, Fortin G. Genetic identification of an embryonic parafacial oscillator coupling to the pre-Botzinger complex. Nat Neurosci. 2009 ; 12: 1028-35
30. Todd AJ. Neuronal circuitry for pain processing in the dorsal horn. Nat Rev Neurosci. 2010 ; 11: 823-36
31. Tripodi M, Stepien AE, Arber S. Motor antagonism exposed by spatial segregation and timing of neurogenesis. Nature. 2011 ; 479: 61-6
32. Waldenstrom A, Christensson M, Schouenborg J. Spontaneous movements: effect of denervation and relation to the adaptation of nociceptive withdrawal reflexes in the rat. Physiol Behav. 2009 ; 98: 532-6
33. Waldenstrom A, Thelin J, Thimansson E, Levinsson A, Schouenborg J. Developmental learning in a pain-related system: evidence for a cross-modality mechanism. J Neurosci. 2003 ; 23: 7719-25
34. Zheng J, Lee S, Zhou ZJ. A transient network of intrinsically bursting starburst cells underlies the generation of retinal waves. Nat Neurosci. 2006 ; 9: 363-71