Late stage benzylic C-H fluorination with [18F]fluoride for PET imaging

Journal of the American Chemical Society

Volumn 136, Issue 19, 2014, Pages 6842-6845

  Huang, Xiongyi ^a   Liu, Wei ^a   Ren, Hong ^b   Neelamegam, Ramesh ^b   Hooker, Jacob M ^b   Groves, John T ^a  

^a PRINCETON UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; FLUORINE COMPOUNDS; MOLECULES;

AUTOMATED SYNTHESIS; BIOACTIVE MOLECULES; BUILDING BLOCKES; C-H BOND; DRUG MOLECULES; LATE STAGE; PET IMAGING; RADIOCHEMICAL YIELD;

ION EXCHANGE;

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CARBON; DIPEPTIDYL CARBOXYPEPTIDASE; FUNCTIONAL GROUP; HYDROGEN; IBUPROFEN; MANGANESE; PHOSPHODIESTERASE; PROSTAGLANDIN SYNTHASE; SODIUM FLUORIDE F 18; DISALICYLALDEHYDE ETHYLENEDIAMINE; ETHYLENEDIAMINE DERIVATIVE; FLUORIDE; FLUORINE; RADIOPHARMACEUTICAL AGENT;

ARTICLE; AUTOMATION; CATALYST; CHEMICAL BOND; FLUORINATION; ION EXCHANGE; MECHANICS; MOLECULE; POSITRON EMISSION TOMOGRAPHY; PRECURSOR; RADIOCHEMISTRY; SYNTHESIS; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; HALOGENATION; PROCEDURES;

CATALYSIS; ETHYLENEDIAMINES; FLUORIDES; FLUORINE RADIOISOTOPES; HALOGENATION; MANGANESE; MODELS, MOLECULAR; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS;

EID: 84900798229     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja5039819     Document Type: Article

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