Flaws in animal studies exploring statins and impact on meta-analysis

European Journal of Clinical Investigation

Volumn 44, Issue 6, 2014, Pages 597-612

  Moja, Lorenzo ^a,b   Pecoraro, Valentina ^a   Ciccolallo, Laura ^c   Dall'Olmo, Luigi ^d   Virgili, Gianni ^e   Garattini, Silvio ^f  

^a IRCCS ISTITUTO ORTOPEDICO GALEAZZI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c EUROPEAN FOOD SAFETY AUTHORITY   (Italy)

^d VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

^e UNIVERSITY OF FLORENCE   (Italy)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

Animal models; Bias; Meta analysis; Translational medical research

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; EFFECT SIZE; EXPERIMENTAL DESIGN; NONHUMAN; PRIORITY JOURNAL; REVIEW; SAMPLE SIZE; ANIMAL; ANIMAL EXPERIMENT; DISEASE MODEL; META ANALYSIS (TOPIC); METHODOLOGY; MOUSE; PUBLISHING; RABBIT; RAT; STANDARDS; STATISTICS;

ANIMAL EXPERIMENTATION; ANIMALS; DISEASE MODELS, ANIMAL; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; META-ANALYSIS AS TOPIC; MICE; PUBLICATION BIAS; RABBITS; RATS; RESEARCH DESIGN; STATISTICS AS TOPIC;

EID: 84900794524     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/eci.12264     Document Type: Review

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