The design and statistical analysis of animal experiments

ILAR Journal

Volumn 43, Issue 4, 2002, Pages 191-193

  Festing, Michael F W ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Animal experiments; Experimental design; Sample size; Statistics; Variation

Indexed keywords

CHEMICAL COMPOUND;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; CIRCADIAN RHYTHM; COMPUTER SIMULATION; DOSE RESPONSE; EDITORIAL; EXPERIMENTAL ANIMAL; FACTORIAL ANALYSIS; GENETIC VARIABILITY; GOOD LABORATORY PRACTICE; LD 50; MEDICAL LITERATURE; MEDICAL RESEARCH; METHODOLOGY; NONHUMAN; RANDOMIZATION; SEX DIFFERENCE; SPECIES DIFFERENCE; STATISTICAL ANALYSIS; STRAIN DIFFERENCE; TOXICITY TESTING;

ANIMALIA;

EID: 0036376150     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.43.4.191     Document Type: Editorial

References (16)

1. Sample size determination
2. The mousetrap: What we can learn when the mouse model does not mimic the human disease
3. Reduction of animal use: Experimental design and quality of experiments
4. Common errors in the statistical analysis of experimental data
5. Guidelines for the design and statistical analysis of experiments using laboratory animals
6. The Design of Animal Experiments: Reducing the Use of Animals in Research Through Better Experimental Design
7. The role of ancillary variables in the design, analysis, and interpretation of animal experiments
8. Mouse models of human disease
9. The control of variability
10. Practical aspects to experimental design in animal research
11. 50 test: The up and down procedure for acute oral toxicity
12. Does animal experimentation inform human healthcare? Observations from a systematic review of international animal experiments on fluid resuscitation
13. The Principles of Humane Experimental Technique
14. 50 test
15. The use of factorial designs to optimize animal experiments and reduce animal use
16. Statistical evaluation of the fixed-dose procedure