Infection control strategies for preventing the transmission of meticillin-resistant Staphylococcus aureus (MRSA) in nursing homes for older people

Cochrane Database of Systematic Reviews

Volumn 2013, Issue 11, 2013, Pages

  Hughes, Carmel ^a   Tunney, Michael ^a   Bradley, Marie C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALL CAUSE MORTALITY; ANTIBIOTIC THERAPY; BACTERIAL TRANSMISSION; CLINICAL AUDIT; HUMAN; INCIDENCE; INFECTION CONTROL; INFECTION PREVENTION; LENGTH OF STAY; MEDICAL EDUCATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; NURSING HOME; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; RISK ASSESSMENT; SCORING SYSTEM; STAPHYLOCOCCUS INFECTION; SYSTEMATIC REVIEW; AGED; CROSS INFECTION; DISEASE TRANSMISSION; DRUG EFFECT; HOME FOR THE AGED; METHODOLOGY;

AGED; CROSS INFECTION; HOMES FOR THE AGED; HUMANS; INFECTION CONTROL; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; NURSING HOMES; STAPHYLOCOCCAL INFECTIONS;

EID: 84900775237     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD006354.pub4     Document Type: Review

References (65)

1. Baldwin NS, Gilpin DF, Tunney MM, Kearney MP, Crymble L, Cardwell C, et al. Cluster randomised controlled trial of an infection control education and training intervention programme focusing on meticillin-resistant Staphylococcus aureus in nursing homes for older people. Journal of Hospital Infection 2011;76(1):36-41.
2. Chami K, Gavazzi G, Bar-Hen A, Carrat F, de Wazieres B, Lejeune B, et al. A short-term, multicomponent infection control program in nursing homes: a cluster randomized controlled trial. Journal of the American Medical Directors' Association 2012;13(6):569.e9-569.e17.
3. Ho M-L, Seto W-H, Wong L-C, Wong T-Y. Effectiveness of multifacted hand hygiene interventions on long-term care facilities in Hong Kong: a cluster-randomized controlled trial. Infection Control and Hospital Epidemiology 2012;33(8):761-767.
4. Horner C, Wilcox M, Barr B, Hall D, Hodgson G, Parnell P, et al. The longitudinal prevalence of MRSA in care home residents and the effectiveness of improving infection prevention knowledge and practice on colonisation using a stepped wedge study design. BMJ Open 2012;2:e000423.
5. Baldwin NS, Gilpin DF, Hughes CM, Kearney MP, Gardiner DA, Cardwell C, et al. Prevalence of meticillin-resistant Staphylococcus aureus (MRSA) colonization among residents and staffin nursing homes in Northern Ireland. Journal of the American Geriatrics Society 2009;57(4):620-6.
6. Bradley SF. Methicillin-resistant Staphylococcus aureus in nursing homes. Epidemiology, prevention and management. Drugs and Aging 1997;10(3):185-98.
7. Burke JP. Infection control-a problem for patient safety. New England Journal of Medicine 2003;348(7):651-6.
8. Campbell NC, Murray E, Darbyshire J, Emery J, Farmer A, et al. Designing and evaluating complex interventions to improve health care. BMJ 2007;334(7591):455-9.
9. Capitano B. Leshem OA, Nightingale CH, Nicolau DP. Cost effect of managing methicillin-resistant Staphylococcus aureus. Journal of the American Geriatrics Society 2003;51(1):10-6.
10. Castle NG, Engberg J. Staffturnover and quality of care in nursing homes. Medical Care 2005;43(6):616-26.
11. Chamchod F, Ruan S. Modeling the spread of Methicillin-resistant Staphylococcus aureus in nursing homes for the elderly. PLoS One 2012;7(1):e29757. [DOI: 10.1371/journal.pone.0029757]
12. Coia JE, Duckworth GJ, Edwards DI, Farrington M, Fry C, Humphreys H, et al. Guidelines for the control and prevention meticillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities. Journal of Hospital Infection 2006;63S:S1-S44.
13. Cooper BS, Stone SP, Kibbler CC, Cookson BD, Roberts JA, Medley GF, et al. Systematic review of isolation policies in the hospital management of methicillin-resistant Staphylococcus aureus: a review of the literature with epidemiological and economic modelling. Health Technology Assessment 2003;7(39):1-194.
14. Cosgrove SE, Sakoulas G, Perencevich EN, Schwaber MJ, Karchmer AW, Carmeli Y. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clinical Infectious Diseases 2003;36(1):53-9.
15. Cox RA, Bowie PE. Methicillin-resistant Staphylococcus aureus colonization in nursing home residents: a prevalence study in Northamptonshire. Journal of Hospital Infection 1999;43:115-22.
16. Department of Health. Infection Control Guidance for Care Homes. Department of Health, London 2006.
17. Drinka PJ, Gauerke C, Le D. Antimicrobial use and meticillin-resistant Staphylococcus aureus in a large nursing home. Journal of the American Medical Directors Association 2004;5(4):256-8.
18. Elon R, Pawlson LG. The impact of OBRA on medical practices within nursing facilities. Journal of the American Geriatrics Society 1992;40(9):958-63.
19. Cochrane Effective Practice and Organisation of Care Group. EPOC Working Paper on presentation of data. http://www.epoc.cochrane.org/en/handsearchers.html (Accessed 8 September 2009).
20. Fraise AP, Mitchell K, O'Brien SJ, Oldfield K, Wise R. Methicillin-resistant Staphylococcus aureus (MRSA) in nursing homes in a major UK city: an anonymized point prevalence survey. Epidemiology and Infection 1997;118(1):1-5.
21. Global Consensus Conference on Infection Control Issues Related to Antimicrobial Resistance 1999. Global Consensus Conference: Final recommendations. American Journal of Infection Control 1999;27:503-13.
22. Goettsch W, Geubbels E, Wannet W, Hendrix MGR, Wagenvoort JHT, de Neeling AJ. MRSA in nursing homes in the Netherlands 1989-1998: a developing reservoir?. Eurosurveillance 2000;5:28-31.
23. Gopal RG, Michalczyk P, Nayeem N, Walker G, Wigmore L. Prevalence and risk factors for meticillin-resistant Staphylococcus aureus in adult emergency admissions-a case for screening all patients?. Journal of Hospital Infection 2007; Vol. 66, issue 1:15-21.
24. Gould DJ, Moralejo D, Drey N, Chudleigh JH. Interventions to improve hand hygiene compliance in patient care. Cochrane Database of Systematic Reviews 2010, Issue 9. [DOI: 10.1002/14651858.CD005186.pub3]
25. Graffunder EM, Venezia RA. Risk factors associated with nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection including previous use of antimicrobials. Journal of Antimicrobial Chemotherapy 1999;49(6):999-1005.
26. Health Statistics Quarterly 2013. Deaths involving MRSA: England and Wales, 2008 to 2012. Health Statistics Quarterly 2013.
27. Herwaldt LA. Control of methicillin-resistant Staphylococcis aureus in the hospital setting. American Journal of Medicine 1999;106(5A):11S-18S.
28. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557-60.
29. Higgins JPT, Altman DG, on behalf of the Cochrane Statistical Methods Group and the Cochrane Bias Methods Group (Editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
30. Hoefnagels-Schuermans A, Niclaes L, Buntinx F, Suetens C, Jans B, Verhaegen J, et al. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in nursing homes: a cross-sectional study. Infection Control and Hospital Epidemiology 2002;23:546-9.
31. Hsu CC. Serial survey of methicillin-resistant Staphylococcus aureus nasal carriage among residents in a nursing home. Infection Control and Hospital Epidemiology 1991;12(7):416-21.
32. Johnson LB, Bhan A, Pawlak J, Manzor O, Saravolatz LD. Changing epidemiology of community-onset methicillin-resistant Staphylococcus aureus bacteremia. Infection Control and Epidemiology 2003;24(6):431-5.
33. Lefebvre C, Manheimer E, Glanville J, on behalf of the Cochrane Information Retrieval Methods Group. Chapter 6: Searching for studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
34. Lesse AJ, Mylotte JM. Clinical and molecular epidemiology of nursing home associated Staphylococcus aureus bacteremia. American Journal of Infection Control 2006;34(10):642-50.
35. Loeb M, Main C, Walker-Dilks C, Eady A. Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization. Cochrane Database of Systematic Reviews 2003, Issue 4. [DOI: 10.1002/14651858.CD003340]
36. MacDonald A, Dinah F, MacKenzie D, Wilson A. Performance feedback of hand hygiene, using alcohol gel as the skin decontaminant, reduces the number of inpatients newly affected by MRSA and antibiotic costs. Journal of Hospital Infection 2004;56(1):56-63.
37. McClean P, Tunney M, Parsons C, Gilpin D, Baldwin N, Hughes C. Infection control and meticillin-resistant Staphylococcus aureus decolonization: the perspective of nursing home staff. Journal of Hospital Infection 2012;81:264-9.
38. Mendelson G, Yearmack Y, Granot E, Ben-Israel J, Colodner R, Raz R. Staphylococcus aureus carrier state among elderly residents of a long-term care facility. Journal of the American Medical Directors' Association 2003;4(3):125-7.
39. Morrow E, Griffiths p, Rao GG, Flaxman D. "Somebody else's problem?" Staffperceptions of the courses and control of meticillin-resistant Staphylococcus aureus. American Journal of Infection Control 2012;39:284-291.
40. Muder RR, Brennen C, Drenning SD, Stout JE, Wagener MM. Multiple antibiotic-resistant gram-negative bacilli in a long-term-care facility: a case-control study of patient risk factors and prior antibiotic use. Infection Control and Hospital Epidemiology 1997;18:809-13.
41. Mulhausen PL, Harrell LJ, Weinberger M, Kochersberger GG, Feussner JR. Contrasting methicillin-resistant Staphylococcus aureus colonization in Veterans Affairs and community nursing homes. American Journal of Medicine 1996;100:24-31.
42. Niclaes L, Buntinx F, Banuro F, Lesaffre E, Heyrman J. Consequences of MRSA carriage in nursing home residents. Epidemiology and Infection 1999;122(2):235-9.
43. O'Sullivan NR, Keane CT. The prevalence of methicillin-resistant staphylococcus aureus among the residents of six nursing homes for the elderly. Journal of Hospital Infection 2000;45(4):322-9.
44. Omnibus Budget Reconciliation Act 1987 (OBRA 87). Omnibus Budget Reconciliation Act 1987 (OBRA 87). Public Law 100-203. Subtitle C: Nursing Home Reform Act, Washington DC 1987.
45. Rubin RJ, Harrington CA, Poon Dietrich K, Greene JA, Moiduddin A. The economic impact of Staphylococcus aureus infection in New York City hospitals. Emerging Infectious Diseases 1999;5:9-17.
46. Safdar N, Maki DG. The commonality of risk factors for nosocomial colonization and infection with antimicrobial-resistant Staphylococcus aureus, Enterococcus, Gram-negative bacilli, Clostridium difficile and Candida. Annals of Internal Medicine 2002;136:834-44.
47. Samad A, Banerjee D, Carbarns N, Ghosh S. Prevalence of methicillin-resistant Staphylococcus aureus colonization in surgical patients on admission to a Welsh hospital. Journal of Hospital Infection 2002;51(1):43-6.
48. Sclaes DM, Gerding DN, John JF Jr. Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Infection Control Hospital Epidemiology 1997;18:275-91.
49. Scottish Intercollegiate Guidelines Network (SIGN). Search filters. http://www.sign.ac.uk/methodology/filters.html#random (accessed 29 May 2009).
50. Simor AE. Containing methicillin-resistant S. aureus. Surveillance, control and treatment methods. Postgraduate Medicine 2001;110:43-8.
51. Smith CS, Parnell P, Hodgson G, Darby B, Barr B, Tompkins D, et al. Are methicillin-resistant Staphylococcus aureus that produce Panton-Valentine leucocidin (PVL) found among residents of care homes?. Journal of Antimicrobial Chemotherapy 2008;62:968-72.
52. Stelfox HT, Bates DW, Redelmeier DA. Safety of patients isolated for infection control. JAMA 2003;290(14):1899-905.
53. Stone SP, Kibbler CC, Bowman C, Stott D. Controlling infection in British nursing homes. BMJ 2001;322:506.
54. Stone SP, Cooper BS, Kibbler CC, Cookson BD, Roberts JA, Medley GF, et al. The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. Journal of Antimicrobial Chemotherapy 2007;59:833-40.
55. Strausbaugh LJ, Crossley KB, Nurse BA, Thrupp LD. Antimicrobial resistance in long-term-care facilities. Infection Control and Hospital Epidemiology 1996;17:129-40.
56. Strausbaugh LJ, Sukumar SR, Joseph CL. Infectious disease outbreaks in nursing homes: an unappreciated hazard for frail elderly persons. Clinical Infectious Diseases 2003;36:870-6.
57. Tarzi S, Kennedy P, Stone S, Evans M. Methicillin-resistant Staphylococcus aureus: psychological impact of hospitalization and isolation on an older adult population. Journal of Hospital Infection 2001;49:250-4.
58. Terpenning MS, Bradley SF, Wan JY, Chenoweth CE, Jorgensen KA, Kauffman CA. Colonization and infection with antibiotic-resistant bacteria in a long-term care facility. Journal of the American Geriatrics Society 1994;42:1062-9.
59. Tomic V, Sorli PS, Trinkaus D, Sorli J, Widmer AF, Trampuz A. Comprehensive strategy to prevent nosocomial spread of methicillin-resistant Staphylococcus aureus in a highly endemic setting. Archives of Internal Medicine 2004;164(18):2038-43.
60. Trick WE, Weinstein RA, DeMarais P, Kuehnert MJ, Tomaska W, Nathan C, et al. Colonization of skilled-care facility residents with antimicrobial-resistant pathogens. Journal of the American Geriatrics Society 2001;49(3):270-6.
61. Tunney MM, Hughes CM, Magee J. Infection control policies and procedures for meticillin-resistant Staphylococcus aureus in care homes for older people in Northern Ireland: a questionnaire study. British Journal of Infection Control 2006;7:20-4.
62. von Baum H, Schmidt C, Svoboda D, Bock-Hensley O, Wendt C. Risk factors for methicillin-resistant Staphylococcus aureus carriage in residents of German nursing homes. Infection Control and Hospital Epidemiology 2002;23(9):511-15.
63. Vos MC, Ott A, Verbrugh HA. Successful search-and-destroy policy for methicillin-resistant Staphylococcus aureus in the Netherlands. Journal of Clinical Microbiology 2005;43(4):2034-5.
64. Weber SG, Huang SS, Oriola S, Huskins WC, Noskin GA, Harriman K, et al. Legislative mandates for use of active surveillance cultures to screen for methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci: Position statement from the Joint SHEA and APIC Task Force. American Journal of Infection Control 2007;35:73-85.
65. Wertheim HFL, Vos MC, Boelens HAM, Voss A, Vandenbroucke-Grauls, Meester MHM, et al. Low prevalence of methicillin-resistant Staphylococcus aureus (MRSA) at hospital admission in the Netherlands: the value of search and destroy and restrictive antibiotic use. Journal of Hospital Infection 2004;56(4):321-5.