Fernando de castro and the discovery of the arterial chemoreceptors

Frontiers in Neuroanatomy

Volumn 8, Issue MAY, 2014, Pages

  Gonzalez, Constancio ^a,b   Conde, Silvia V ^a,b   Gallego Martín, Teresa ^a,b   Olea, Elena ^a,b   Gonzalez Obeso, Elvira ^a,b   Ramirez, Maria ^a,b   Yubero, Sara ^a,b   Agapito, Maria T ^a,b   Gomez Niño, Angela ^a,b   Obeso, Ana ^a,b   Rigual, Ricardo ^a,b   Rocher, Asunción ^a,b  

^a UNIVERSITY OF VALLADOLID   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Arterial chemoreceptorss; Carotid body; Fernando de Castro; Ion channels; Sensory physiology; Transduction cascade

Indexed keywords

CARMINIC ACID; NEUROTRANSMITTER; SILVER NITRATE;

BRAIN STEM; CAROTID BODY CHEMORECEPTOR; CAROTID SINUS PRESSORECEPTOR REFLEX; CATECHOLAMINE BLOOD LEVEL; CELL HYPOXIA; CHOLINERGIC ACTIVITY; CHROMAFFIN SYSTEM; GANGLION; GLOMERULUS; GLOSSOPHARYNGEAL NERVE; GOLGI COMPLEX; HUMAN; MITOCHONDRION; MYELINATED NERVE; NERVE ENDING; NEUROTRANSMISSION; NONHUMAN; NONMYELINATED NERVE; PARAGANGLION; PRESSORECEPTOR; REFLEX; REVIEW; SENSORY NERVE; SYMPATHETIC INNERVATION; SYMPATHETIC TRUNK;

EID: 84900566015     PISSN: None     EISSN: 16625129     Source Type: Journal    
DOI: 10.3389/fnana.2014.00025     Document Type: Review

References (50)

1. Adams, W. E. (1958). The Comparative Morphology of the CB and Carotid Simus. Springfield, IL: Charles C. Thomas Publisher.
2. Almaraz, L., Wang, Z. Z., Dinger, B., and Fidone, S. (1997). "Neurotransmitter mediation of carotid chemoreceptor efferent inhibition," in The Carotid Body Chemoreceptors, ed. C. Gonzalez (New York: Springer-Verlag), 47-158.
3. Belmonte, C., and Gallego, R. (1983). Membrane properties of cat sensory neurones with chemoreceptor and baroreceptor endings. J. Physiol. 342, 603-614.
4. Böck, P., and Gorgas, K. (1976). Fine structure of baroreceptor terminals in the carotid sinus of guinea pigs and mice. Cell Tissue Res. 170, 95-112. doi: 10.1007/BF00220113
5. Campanucci, V. A., Dookhoo, L., Vollmer, C., and Nurse, C. A. (2012). Modulation of the carotid body sensory discharge by NO: an up-dated hypothesis. Respir. Physiol. Neurobiol. 184, 49-57. doi: 10.1016/j.resp.2012.04.005
6. Conde, S. V., Monteiro, E. C., Rigual, R., Obeso, A., and Gonzalez, C. (2012). Hypoxic intensity: a determinant for the contribution of ATP and adenosine to the genesis of carotid body chemosensory activity. J. Appl. Physiol. 112, 2002-2010. doi: 10.1152/japplphysiol.01617.2011
7. Conde, S. V., and Peers, C. (2013). Carotid body chemotransduction gets the human touch. J. Physiol. 591(Pt 24):6131-6132. doi: 10.1113/jphysiol.2013.267625
8. De Carlos, J. A., and Borrell, J. (2007). A historical reflection of the contributions of Cajal and Golgi to the foundations of neuroscience. Brain Res. Rev. 55, 8-16. doi: 10.1016/j.brainresrev.2007.03.010
9. de Castro, F. (1926). Sur la structure et l'innervation de la glande intercarotidienne (glomus caroticum) de l'homme et des mammifères, et sur un nouveau système d'innervation autonome du nerf glossopharyngien. Trab. Lab. Invest. Biol. Univ. Madrid 24, 365-432.
10. de Castro, F. (1928). Sur la structure et l'innervation du sinus carotidien de l'homme et des mammifères: nouveaux faits sur l'innervation et la fonction du glomus caroticum. Trab. Lab. Invest. Biol. Univ. Madrid 25, 330-380.
11. de Castro, F. (1940). Nuevas observaciones sobre la inervación de la región carotídea. Trab. Inst. Cajal Invest. Biol. 32, 297-384.
12. de Castro, F. (1951). Sur la structure de la synapse dans chemocepteurs: leur mécan-isme d'excitation et rôle dans la circulation sanguine locale. Acta Physiol. Scand. 22, 14-43. doi: 10.1111/j.1748-1716.1951.tb00747.x
13. Drüner, L. (1925). Ueber die anatomischen Unterlagen der Sinusreflexe Herings. Dtsch. Med. Wochenschr. 51, 559-560. doi: 10.1055/s-0028-1136629
14. Eyzaguirre, C., and Lewin, J. (1961). The effect of sympathetic stimulation on carotid nerve activity. J. Physiol. 159, 251-267.
15. Fidone, S., and Gonzalez, C. (1986). "Initiation and control of chemorecep-tor activity in the carotid body," in Handbook of Physiology. The Respiratoy System, ed. A. P. Fishman (Bethesda, MD: American Physiological Society), 247-312.
16. Fitzgerald, R., and Lahiri, S. (1986). "Reflex responses to chemoreceptor stimulation," in Handbook of Physiology-The Respiratory System, Vol. 2, ed. A. Fishman (Bethesda: American Physiological Society), 313-362.
17. Fitzgerald, R. S., and Shirahata, M. (1997). "Systemic responses elicited by stimulating the carotid body: primary and secondary mechanisms," in The Carotid Body Chemoreceptors, ed. C. Gonzalez (Berlin: Springer-Verlag), 171-191.
18. Gauda, E. B., Cooper, R., Johnson, S. M., McLemore, G. L., and Marshall, C. (2004). Autonomic microganglion cells: a source of acetylcholine in the rat carotid body. J. Appl. Physiol. 96, 384-391. doi: 10.1152/japplphysiol.00897.2003
19. Gonzalez, C., Agapito, M. T., Rocher, A., Gomez-Niño, A., Rigual, R., Castañeda, J., et al. (2010). A revisit to O2 sensing and transduction in the carotid body chemoreceptors in the context of reactive oxygen species biology. Respir. Physiol. Neurobiol. 174, 317-330. doi: 10.1016/j.resp.2010.09.002
20. González, C., Almaraz, L., Obeso, A., and Rigual, R. (1992). Oxygen and acid chemoreception in the carotid body chemoreceptors. Trends Neurosci. 15, 146-153. doi: 10.1016/0166-2236(92)90357-E
21. Gonzalez, C., Almaraz, L., Obeso, A., and Rigual, R. (1994). Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74, 829-898.
22. Gonzalez, C., Dinger, B., and Fidone, S. (1997). "Functional significance of chemoreceptor cells neurotransmitters," in The Carotid Body Chemoreceptors, ed. C. Gonzalez (New York: Springer-Verlag), 47-63.
23. Hempleman, S. C., and Warburton, S. J. (2013). Comparative embryology of the carotid body. Respir. Physiol. Neurobiol. 185, 3-8. doi: 10.1016/j.resp.2012. 08.004
24. Heymans, C., Bouckaert, J., and Dautrebande, L. (1930). Sinus carotidien et réflexes respiratoires II. Influences respiratoires réflexes de l'acidose, de l'alcalose, de l'anhydride carbonique, de l'ion hydrogene et de l'anoxémie: sinus carotidiens et e'changes respiratoires dans les poumons et au dela des poumons. Arch. Int. Pharmacodyn. Ther. 39, 400-408.
25. Iturriaga, R., Alcayaga, J., and Gonzalez, C. (2009). Neurotransmitters in carotid body function: the case of dopamine-invited article. Adv. Exp. Med. Biol. 648, 137-143. doi: 10.1007/978-90-481-2259-2_16
26. Kameda, Y. (2009). Hoxa3 and signaling molecules involved in aortic arch patterning and remodeling. Cell Tissue Res. 336, 165-178. doi: 10.1007/s00441-009-0760-7
27. Lack, E. E., Perez-Atayde, A. R., and Young, J. B. (1985). CB hyperplasia in cystic fibrosis and cyanotic heart disease. A combined morphometric, ultrastructural, and biochemical study. Am. J. Pathol. 119, 301-314.
28. Lahiri, S., Matsumoto, S., and Mokashi, A. (1986). Responses of ganglioglomerular nerve activity to respiratory stimuli in the cat. J. Appl. Physiol. 60, 391-397.
29. Le Douarin, N., Le Lièvre, C., and Fontaine, J. (1972). Experimental research on the embryologic origin of the CB in birds. C. R. Acad. Sci. Hebd. Seances Acad. Sci. D 275, 583-586.
30. Lever, J. D., and Boyd, J. D. (1957). Osmiophile granules in the glomus cells of the rabbit carotid body. Nature 179, 1082-1083. doi: 10.1038/1791082b0
31. Lever, J. D., Lewis, P. R., and Boyd, J. D. (1959). Observations on the fine structure and histochemistry of the carotid body in the cat and rabbit. J. Anat. 93, 478-490.
32. + current modulated by PO2 in type I chemoreceptor cells. Science 241, 580-582. doi: 10.1126/science.2456613
33. McDonald, D. M. (1981). "Peripheral chemoreceptors. Structure-function relationships of the carotid body," in Regulation of Breathing, ed. T. F. Hornbein (New York: Marcel Dekker, Inc.), 105-319.
34. Nishi, K., and Stensaas, L. J. (1974). The ultrastructure and source of nerve endings in the carotid body. Cell Tissue Res. 154, 303-319. doi: 10.1007/BF00223728
35. Noble, E. R., Smoker, W. R., and Ghatak, N. R. (1997). Atypical skull base paragangliomas. Am. J. Neuroradiol. 18, 986-990.
36. Nurse, C. A. (2010). Neurotransmitter and neuromodulatory mechanisms at peripheral arterial chemoreceptors. Exp. Physiol. 95, 657-667. doi: 10.1113/exp-physiol.2009.049312
37. Paton, J. F., Sobotka, P. A., Fudim, M., Engelman, Z. J., Hart, E. C., McBryde, F. D., et al. (2013). The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases. Hypertension 61, 5-13. doi: 10.1161/HYPER-TENSIONAHA.111.00064
38. Pearse, A. G., Polak, J. M., Rost, F. W., Fontaine, J., Le Lièvre, C., and Le Douarin, N. (1973). Demonstration of the neural crest origin of type I (APUD) cells in the avian CB, using a cytochemical marker system. Histochemie 34, 191-203. doi: 10.1007/BF00303435
39. Pérez-García, M. T., López-López, J. R., and González, C. (1999). Kvbeta1.2 subunit coexpression in HEK293 cells confers O2 sensitivity to Kv4.2 but not to Shaker channels. J. Gen. Physiol. 113, 897-907. doi: 10.1085/jgp.113.6.897
40. Perrin, D. G., Cutz, E., Becker, L. E., Bryan, A. C., Madapallimatum, A., and Sole, M. J. (1984). Sudden infant death syndrome: increased carotid-body dopamine and noradrenaline content. Lancet 2, 535-537. doi: 10.1016/S0140-6736(84)90763-3
41. Prabhakar, N. R., and Peers, C. (2014). Gasotransmitter regulation of ion channels: a key step in o2 sensing by the carotid body. Physiology (Bethesda) 29, 49-57. doi: 10.1152/physiol.00034.2013
42. Ribeiro, M. J., Sacramento, J. F., Gonzalez, C., Guarino, M. P., Monteiro, E. C., and Conde, S. V. (2013). Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets. Diabetes 62, 2905-2916. doi: 10.2337/db12-1463
43. Rocher, A., Caceres, A. I., Almaraz, L., and Gonzalez, C. (2009). EPAC signalling pathways are involved in low PO2 chemoreception in carotid body chemoreceptor cells. J. Physiol. 587(Pt 16), 4015-4027. doi: 10.1113/jphysiol.2009.172072
44. Sanz-Alfayate, G., Obeso, A., Agapito, M. T., and González, C. (2001). Reduced to oxidized glutathione ratios and oxygen sensing in calf and rabbit carotid body chemoreceptor cells. J. Physiol. 537(Pt 1), 209-220. doi: 10.1111/j.1469-7793.2001.0209k.x
45. Tubbs, R. S., Vahedi, P., Loukas, M., Shoja, M. M., and Cohen-Gadol, A. A. (2011). Hubert von Luschka (1820-1875): his life, discoveries, and contributions to our understanding of the nervous system. J. Neurosurg. 114, 268-272. doi: 10.3171/2010.8.JNS10683
46. Verna, A. (1997). "The mammalian carotid body: morphological data," in The Carotid Body Chemoreceptors, ed. C. Gonzalez (New York: Springer), 1-29.
47. Verna, A. (1979). Ultrastructure of the carotid body in the mammals. Int. Rev. Cytol. 60, 271-330. doi: 10.1016/S0074-7696(08)61265-6
48. Wang, Z. Z., Stensaas, L. J., Dinger, B., and Fidone, S. J. (1995). Nitric oxide mediates chemoreceptor inhibition in the carotid body. Neuroscience 65, 217-229. doi: 10.1016/0306-4522(94)00437-A
49. Welander, J., Söderkvist, P., and Gimm, O. (2011). Genetics and clinical characteristics of hereditary pheochromocytomas and paragangliomas. Endocr. Relat. Cancer 18, R253-R276. doi: 10.1530/ERC-11-0170
50. Yates, R. D., and Chen, I. (1980). An electron microscopic study of the baroreceptors in the internal carotid artery of the spontaneously hypertensive rat. Cell Tissue Res. 205, 473-483. doi: 10.1007/BF00232287