Gliotoxin-induced swelling of astrocytes hinders diffusion in brain extracellular space via formation of dead-space microdomains

GLIA

Volumn 62, Issue 7, 2014, Pages 1053-1065

  Sherpa, Ang Doma ^a   van de Nes, Paula ^a   Xiao, Fanrong ^a,b   Weedon, Jeremy ^a   Hrabetova, Sabina ^a,b  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b SUNY Downstate Medical Center   (United States)

Author keywords

DL aminoadipic acid; Rat; Somatosensory neocortex; Tortuosity; Volume fraction

Indexed keywords

2 AMINOADIPIC ACID; GLIOTOXIN; POTASSIUM;

ADULT; ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN; BRAIN SLICE; BRAIN TISSUE; CELL MEMBRANE; CELL SWELLING; CELLULAR PARAMETERS; CONTROLLED STUDY; DEAD SPACE MICRODOMAIN; DIFFUSION; DIFFUSION COEFFICIENT; EXTRACELLULAR SPACE; FEMALE; FLUORESCENCE IMAGING; IMMUNOHISTOCHEMISTRY; INTEGRATIVE OPTICAL IMAGING; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME IONTOPHORETIC DIFFUSION METHOD; SOMATOSENSORY NEOCORTEX; ANIMAL; CELL SIZE; CONFOCAL MICROSCOPY; DRUG EFFECTS; METABOLISM; MICROELECTRODE; PATHOPHYSIOLOGY; PHYSIOLOGY; SOMATOSENSORY CORTEX; SPRAGUE DAWLEY RAT; TOXICITY;

2-AMINOADIPIC ACID; ANIMALS; ASTROCYTES; CELL SIZE; DIFFUSION; EXTRACELLULAR SPACE; FEMALE; GLIOTOXIN; IMMUNOHISTOCHEMISTRY; MICROELECTRODES; MICROSCOPY, CONFOCAL; OPTICAL IMAGING; POTASSIUM; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX;

EID: 84900563185     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22661     Document Type: Article

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