TIMI frame count and adverse events in women with no obstructive coronary disease: A pilot study from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE)

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Petersen, John W ^a   Johnson, B Delia ^b   Kip, Kevin E ^c   Anderson, R David ^a   Handberg, Eileen M ^a   Sharaf, Barry ^d   Mehta, Puja K ^e   Kelsey, Sheryl F ^b   Bairey Merz, C Noel ^e   Pepine, Carl J ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d BROWN UNIVERSITY   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; BLOOD CLOT LYSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR PARAMETERS; CAUCASIAN; CEREBROVASCULAR ACCIDENT; COHORT ANALYSIS; CORONARY ARTERY DISEASE; DEATH; FEMALE; FOLLOW UP; HEART FAILURE; HEART INFARCTION; HOSPITALIZATION; HUMAN; HYPERTENSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MAJOR CLINICAL STUDY; MEDICAL HISTORY; OUTCOME ASSESSMENT; PILOT STUDY; PREDICTIVE VALUE; SMOKING; THROMBOLYSIS IN MYOCARDIAL INFARCTION FRAME COUNT; WOMEN'S HEALTH; ARTERY; CLINICAL TRIAL; MIDDLE AGED; NATIONAL HEALTH ORGANIZATION; PATHOPHYSIOLOGY; UNITED STATES;

ARTERIES; CORONARY DISEASE; FEMALE; HOSPITALIZATION; HUMANS; MIDDLE AGED; MYOCARDIAL INFARCTION; NATIONAL HEART, LUNG, AND BLOOD INSTITUTE (U.S.); PILOT PROJECTS; UNITED STATES; WOMEN'S HEALTH;

EID: 84900534694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096630     Document Type: Article

References (27)

1. Ong P, Athanasiadis A, Borgulya G, Mahrholdt H, Kaski JC, et al. (2012) High prevalence of a pathological response to acetylcholine testing in patients with stable angina pectoris and unobstructed coronary arteries. The ACOVA Study (Abnormal COronary VAsomotion in patients with stable angina and unobstructed coronary arteries). J Am Coll Cardiol 59: 655-662.
2. Jespersen L, Hvelplund A, Abildstrøm SZ, Pedersen F, Galatius S, et al. (2012) Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events. Eur Heart J 33: 734-744.
3. Gulati M, Cooper-DeHoff RM, McClure C, Johnson BD, Shaw LJ, et al. (2009) Adverse cardiovascular outcomes in women with nonobstructive coronary artery disease: a report from the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project. Arch Intern Med 169: 843-850.
4. Reis SE, Holubkov R, Conrad Smith AJ, Kelsey SF, Sharaf BL, et al. (2001) Coronary microvascular dysfunction is highly prevalent in women with chest pain in the absence of coronary artery disease: results from the NHLBI WISE study. Am Heart J 141: 735-741. (Pubitemid 32378481)
5. von Mering GO, Arant CB, Wessel TR, McGorray SP, Bairey Merz CN, et al. (2004) Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE). Circulation 109: 722-725. (Pubitemid 38222890)
6. Halcox JP, Schenke WH, Zalos G, Mincemoyer R, Prasad A, et al. (2002) Prognostic value of coronary vascular endothelial dysfunction. Circulation 106: 653-658. (Pubitemid 34851922)
7. Schächinger V, Britten MB, Zeiher AM (2000) Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101: 1899-1906. (Pubitemid 30225269)
8. Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR, et al. (2000) Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation 101: 948-954. (Pubitemid 30131694)
9. Pepine CJ, Anderson RD, Sharaf BL, Reis SE, Smith KM, et al. (2010) Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study. J Am Coll Cardiol 55: 2825-2832.
10. Gibson CM, Cannon CP, Daley WL, Dodge JT Jr, Alexander B Jr, et al. (1996) TIMI frame count: a quantitative method of assessing coronary artery flow. Circulation 93: 879-888. (Pubitemid 26074824)
11. Abaci A, Oguzhan A, Eryol NK, Ergin A (1999) Effect of potential confounding factors on the thrombolysis in myocardial infarction (TIMI) trial frame count and its reproducibility. Circulation 100: 2219-2223.
12. Dodge JT Jr, Rizzo M, Nykiel M, Altmann J, Hobkirk K, et al. (1998) Impact of injection rate on the Thrombolysis in Myocardial Infarction (TIMI) trial frame count. Am J Cardiol 81: 1268-1270. (Pubitemid 28226151)
13. Umman B, Nisanci Y, Sezer M, Umman S, Yilmaz E, et al. (2002) The relationship between corrected TIMI frame count and myocardial fractional flow reserve. J Invasive Cardiol 14: 125-128. (Pubitemid 34252717)
14. Lee S, Otsuji Y, Minagoe S, Hamasaki S, Toyonaga K, et al. (2005) Correlation between distal left anterior descending artery flow velocity by transthoracic Doppler echocardiography and corrected TIMI frame count before mechanical reperfusion in patients with anterior acute myocardial infarction. Circ J 69: 1022-1028. (Pubitemid 41603085)
15. Mavrogeni SI, Manginas A, Papadakis E, Douskou M, Cokkinos D, et al. (2005) Coronary flow evaluation by TIMI frame count and magnetic resonance flow velocity in patients with coronary artery ectasia. J Cardiovasc Magn Reson 7: 545-550. (Pubitemid 40770331)
16. Ozdemir N, Kaymaz C, Kirma C, Akcay M, Yuce M, et al. (2003) Intravascular ultrasound correlates of corrected TIMI framecount. Jpn Heart J 44: 213-224. (Pubitemid 41519020)
17. Gibson CM, Murphy SA, Rizzo MJ, Ryan KA, Marble SJ, et al. (1999) Relationship between TIMI frame count and clinical outcomes after thrombolytic administration. Thrombolysis In Myocardial Infarction (TIMI) Study Group. Circulation 99: 1945-1950. (Pubitemid 29183889)
18. Gibson CM, Cannon CP, Murphy SA, Marble SJ, Barron HV, et al; TIMI Study Group (2002) Relationship of the TIMI myocardial perfusion grades, flow grades, frame count, and percutaneous coronary intervention to long-term outcomes after thrombolytic administration in acute myocardial infarction. Circulation 105: 1909-1013.
19. French JK, Hyde TA, Straznicky IT, Andrews J, Lund M, et al. (2000) Relationship between corrected TIMI frame counts at three weeks and late survival after myocardial infarction. J Am Coll Cardiol 35: 1516-1524. (Pubitemid 30307495)
20. Merz CN, Kelsey SF, Pepine CJ, Reichek N, Reis SE, et al. (1999) The Women's Ischemia Syndrome Evaluation (WISE) study: protocol design, methodology and feasibility report. J Am Coll Cardiol 33: 1453-1461.
21. Sharaf BL, Pepine CJ, Kerensky RA, Reis SE, Reichek N, et al. (2001) Detailed angiographic analysis of women with suspected ischemic chest pain (pilot phase data from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation [WISE] Study Angiographic Core Laboratory). Am J Cardiol 87: 937-941; A3.
22. Pauly DF, Johnson BD, Anderson RD, Handberg EM, Smith KM, et al. (2011) In women with symptoms of cardiac ischemia, nonobstructive coronary arteries, and microvascular dysfunction, angiotensin-converting enzyme inhibition is associated with improved microvascular function: A double-blind randomized study from the National Heart, Lung and Blood Institute Women's Ischemia Syndrome Evaluation (WISE). Am Heart J 162: 678-684
23. Erdogan D, Caliskan M, Gullu H, Sezqin AT, Yildirir A, et al. (2007) Coronary flow reserve is impaired in patients with slow coronary flow. Atherosclerosis 191: 168-174 (Pubitemid 46237628)
24. Manginas A, Gatzov P, Chasikidis C, Voudris V, Pavlides G, et al. (1999) Estimation of coronary flow reserve using the Thrombolysis In Myocardial Infarction (TIMI) frame count method. Am J Cardiol 83: 1562-1565, A7.
25. Barcin C, Denktas AE, Garratt KN, Higano ST, Holmes DR, et al. (2003) Relation of Thrombolysis in Myocardial Infarction (TIMI) frame count to coronary flow parameters. Am J Cardiol 91: 466-469. (Pubitemid 36183572)
26. Sun H, Fukumoto Y, Ito A, Shimokawa H, Sunagawa K (2005) Coronary microvascular dysfunction in patients with microvascular angina: analysis by TIMI frame count. J Cardiovasc Pharmacol 46: 622-626. (Pubitemid 41527755)
27. Chugh SK, Koppel J, Scott M, Shewchuk L, Goodhart D, et al. (2004) Coronary flow velocity reserve does not correlate with TIMI frame count in patients undergoing non-emergency percutaneous coronary intervention. J Am Coll Cardiol 44: 778-782. (Pubitemid 39099572)