Expression and function of a T-type Ca2+ conductance in interstitial cells of Cajal of the murine small intestine

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 7, 2014, Pages

  Zheng, Haifeng ^a   Park, Kyung Sik ^b   Koh, Sang Don ^a   Sanders, Kenton M ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^b Keimyung University School of Medicine   (South Korea)

Author keywords

Gastrointestinal motility; Gastrointestinal smooth muscle; Pacemaker; Slow wave

Indexed keywords

BARIUM ION; CALCIUM CHANNEL T TYPE; CALCIUM ION; MIBEFRADIL; NICARDIPINE; NICKEL; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CONDUCTANCE; CALCIUM CURRENT; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; INTERSTITIAL CELL OF CAJAL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMALL INTESTINE; TEMPERATURE DEPENDENCE; TEMPERATURE SENSITIVITY;

GASTROINTESTINAL MOTILITY; GASTROINTESTINAL SMOOTH MUSCLE; PACEMAKER; SLOW WAVE;

ANIMALS; BARIUM; BIOLOGICAL CLOCKS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; CALCIUM SIGNALING; CELLS, CULTURED; GASTROINTESTINAL MOTILITY; INTERSTITIAL CELLS OF CAJAL; ION CHANNEL GATING; JEJUNUM; KINETICS; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; TEMPERATURE;

EID: 84900525723     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00390.2013     Document Type: Article

References (40)

1. 2+ currents are necessary for slow-wave propagation in the canine gastric antrum. Am J Physiol Cell Physiol 293: C1645-C1659, 2007.
2. Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, Pfeffer U, Ravazzolo R, Zegarra-Moran O, Galietta LJ. TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science 322: 590-594, 2008.
3. Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J. International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels. Pharmacol Rev 57: 411-425, 2005.
4. Dickens EJ, Hirst GD, Tomita T. Identification of rhythmically active cells in guinea-pig stomach. J Physiol 514: 515-531, 1999.
5. Edwards FR, Hirst GD. An electrical analysis of slow wave propagation in the guinea-pig gastric antrum. J Physiol 571: 179-189, 2006.
6. 2+ channel subunit is expressed in mouse jejunal interstitial cells of Cajal and myocytes. J Cell Mol Med 13: 4422-4431, 2009.
7. Goto K, Matsuoka S, Noma A. Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine. J Physiol 559: 411-422, 2004.
8. Hennig GW, Hirst GD, Park KJ, Smith CB, Sanders KM, Ward SM, Smith TK. Propagation of pacemaker activity in the guinea-pig antrum. J Physiol 556: 585-599, 2004.
9. - channels. J Physiol 540: 907-919, 2002.
10. Hirst GD, Edwards FR. Generation of slow waves in the antral region of guinea-pig stomach-a stochastic process. J Physiol 535: 165-180, 2001.
11. Huizinga JD, Thuneberg L, Kluppel M, Malysz J, Mikkelsen HB, Bernstein A. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373: 347-349, 1995.
12. Hwang SJ, Blair PJ, Britton FC, O'Driscoll KE, Hennig G, Bayguinov YR, Rock JR, Harfe BD, Sanders KM, Ward SM. Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles. J Physiol 587: 4887-4904, 2009.
13. Iftinca M, McKay BE, Snutch TP, McRory JE, Turner RW, Zamponi GW. Temperature dependence of T-type calcium channel gating. Neuroscience 142: 1031-1042, 2006.
14. 2+ oscillations. Biophys J 90: 1-23, 2006.
15. Kim YC, Koh SD, Sanders KM. Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine. J Physiol 541: 797-810, 2002.
16. Kito Y, Suzuki H. Effects of temperature on pacemaker potentials in the mouse small intestine. Pflügers Arch 454: 263-275, 2007.
17. Kito Y, Suzuki H. Properties of pacemaker potentials recorded from myenteric interstitial cells of Cajal distributed in the mouse small intestine. J Physiol 553: 803-818, 2003.
18. Kito Y, Ward SM, Sanders KM. Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine. Am J Physiol Cell Physiol 288: C710-C720, 2005.
19. Langton P, Ward SM, Carl A, Norell MA, Sanders KM. Spontaneous electrical activity of interstitial cells of Cajal isolated from canine proximal colon. Proc Natl Acad Sci USA 86: 7280-7284, 1989.
20. 2+ inhibition. Proc Natl Acad Sci USA 95: 15821-15825, 1998.
21. 3-sensitive calcium release in the murine small intestine. Am J Physiol Gastrointest Liver Physiol 280: G439-G448, 2001.
22. 2+ release in rat megakaryocytes requires functional IP3 receptors. J Physiol 533: 175-183, 2001.
23. Nakamura E, Kito Y, Hashitani H, Suzuki H. Metabolic component of the temperature-sensitivity of slow waves recorded from gastric muscle of the guinea-pig. J Smooth Muscle Res 42: 33-48, 2006.
24. Nose K, Suzuki H, Kannan H. Voltage dependency of the frequency of slow waves in antrum smooth muscle of the guinea-pig stomach. Jpn J Physiol 50: 625-633, 2000.
25. Ordog T, Ward SM, Sanders KM. Interstitial cells of Cajal generate electrical slow waves in the murine stomach. J Physiol 518: 257-269, 1999.
26. 2+, and tension in intact smooth muscles. Am J Physiol Cell Physiol 260: C917-C925, 1991.
27. Park KJ, Hennig GW, Lee HT, Spencer NJ, Ward SM, Smith TK, Sanders KM. Spatial and temporal mapping of pacemaker activity in interstitial cells of Cajal in mouse ileum in situ. Am J Physiol Cell Physiol 290: C1411-C1427, 2006.
28. Sanders KM. A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract. Gastroenterology 111: 492-515, 1996.
29. Sanders KM. Ionic mechanisms of electrical rhythmicity in gastrointestinal smooth muscles. Annu Rev Physiol 54: 439-453, 1992.
30. Sanders KM, Koh SD, Ward SM. Interstitial cells of cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 68: 307-343, 2006.
31. Schroeder BC, Cheng T, Jan YN, Jan LY. Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell 134: 1019-1029, 2008.
32. Tomita T. Electrical activity (spikes and slow waves) in gastrointestinal smooth muscle. In: Smooth Muscle, An Assessment of Current Knowledge. Austin, TX: Univ. of Texas Press, 1981, p. 127-156.
33. Torihashi S, Ward SM, Nishikawa S, Nishi K, Kobayashi S, Sanders KM. c-kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tissue Res 280: 97-111, 1995.
34. 2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus. J Physiol 548: 271-296, 2003.
35. 2+ uptake in canine colonic muscles. J Physiol 549: 207-218, 2003.
36. Ward SM, Burns AJ, Torihashi S, Sanders KM. Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol 480: 91-97, 1994.
37. 2+ currents of gastric and colonic smooth muscle by phosphatase inhibitors. Am J Physiol Cell Physiol 261: C64-C70, 1991.
38. Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U. TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature 455: 1210-1215, 2008.
39. - conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity. J Physiol 587: 4905-4918, 2009.
40. - current in interstitial cells of Cajal. J Physiol 589: 4565-4582, 2011.