Effect of long-term dietary Arginyl-Fructose (AF) on hyperglycemia and HbA1c in diabetic db/db mice

International Journal of Molecular Sciences

Volumn 15, Issue 5, 2014, Pages 8352-8359

  Lee, Kwang Hyoung ^a   Ha, Kyoung Soo ^b   Jo, Sung Hoon ^b   Lee, Chong M ^c   Kim, Young Cheul ^d   Chung, Kwang Hoe ^a   Kwon, Young In ^b  

^a CHA University   (South Korea)

^b Hannam University   (South Korea)

^c UNIVERSITY OF RHODE ISLAND   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Arginyl fructose (AF); Blood glucose; Pre diabetes; Type 2 diabetes; glucosidase inhibition

Indexed keywords

ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; ARGINYL FRUCTOSE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; FRUCTOSE; GLUCOSE BLOOD LEVEL; GLYCOSIDASE INHIBITOR; GLYCOSYLATED HEMOGLOBIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOPSY; BLOOD ANALYSIS; BODY WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME INHIBITION; FOOD INTAKE; GLUCOSE ABSORPTION; GLUCOSE BLOOD LEVEL; HEMATOLOGY ANALYZER; HYPERGLYCEMIA; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; ANALOGS AND DERIVATIVES; ANALYSIS; ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; COMPLICATION; DIET THERAPY; DRUG EFFECTS;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DIETARY SUPPLEMENTS; FRUCTOSE; GLYCOSIDE HYDROLASE INHIBITORS; HEMOGLOBIN A, GLYCOSYLATED; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; MALE; MICE; MICE, INBRED C57BL;

EID: 84900490158     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15058352     Document Type: Article

References (19)

1. Wild, S.; Roglic, G.; Green, A.; Sicree, R.; King, H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27, 1047-1053.
2. Center for Disease Control. Available online: http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf (accessed on 15 February 2014).
3. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 2002, 25, S5-S20.
4. Deshpande, M.C.; Venkateswarlu, V.; Babu, R.K.; Trivedi, R.K. Design and evaluation of oral bioadhesive controlled release formulations of miglitol, intended for prolonged inhibition of intestinal α-glucosidases and enhancement of plasma glycogen like peptide-1 levels. Int. J. Pharm. 2009, 380, 16-24.
5. Hirsh, A.J.; Yao, S.Y.; Young, J.D.; Cheeseman, C.I. Inhibition of glucose absorption in the rat jejunum: A novel action of α-D-glucosidase inhibitors. Gastroenterology 1997, 113, 205-211.
6. Ha, K.S.; Jo, S.H.; Kang, B.H.; Apostolidis, E.; Lee, M.S.; Jang, H.D.; Kwon, Y.I. In vitro and in vivo antihyperglycemic effect of 2 amadori rearrangement compounds, arginyl-fructose and arginyl-fructosyl-glucose. J. Food Sci. 2011, 76, 188-193.
7. Keum, Y.S.; Park, K.K.; Lee, J.M.; Chun, K.S.; Park, H.P.; Lee, S.K.; Kwon, H.J.; Surh, Y.J. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett. 2000, 150, 41-48.
8. Kaneko, H.; Nakanishi, K.J. Proof of the mysterious efficacy of ginseng: Basic and clinical trials: Clinical effects of medicinal ginseng, Korean red ginseng: Specifically, its anti-stress action for prevention of disease. J. Pharm. Sci. 2004, 95, 158-162.
9. Cho, E.J.; Piao, X.L.; Jang, M.H.; Baek, S.H.; Kim, H.Y.; Kang, K.S.; Kwon, S.W.; Park, J.H. The effect of steaming on the free amino acid contents and antioxidant activity of Panax ginseng. Food Chem. 2008, 107, 876-882.
10. Takaku, T.; Han, L.K.; Kameda, K.; Ninomiya, H.; Okuda, H. Production of arginyl-frictosyl glucose during processing of red ginseng. J. Tradit. Med. 1996, 13, 118-123.
11. Suzuki, Y.; Choi, K.J.; Uchida, K.; Ko, S.R.; Sohn, H.J.; Park, J.D. Arginyl-fructosyl-glucose and arginyl-fructose, compounds related to browning reaction in the model system of steaming and heat-drying processes for the preparation of red ginseng. J. Ginseng Res. 2004, 28, 143-148.
12. Dehghan-Kooshkghazi, M.; Mathers, J.C. Starch digestion, largebowel fermentation and intestinal mucosal cell proliferation in rats treated with the α-glucosidase inhibitor acarbose. Br. J. Nutr. 2004, 91, 357-365.
13. Kim, G.N.; Kwon, Y.I.; Jang, H.D. Mulberry leaf extract reduces postprandial hyperglycemia with few side effects by inhibiting α-glucosidase in normal rats. J. Med. Food 2011, 14, 712-717.
14. Stratton, I.M.; Adler, A.I.; Neil, H.A.W.; Matthews, D.R.; Manley, S.E.; Cull, C.A.; Hadden, D.; Turner, R.C.; Holman, R.R. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study. Br. Med. J. 2000, 321, 405-412.
15. Jo, S.H.; Ha, K.S.; Moon, K.S.; Kim, J.G.; Oh, C.G.; Kim, Y.C.; Apostolidis, E.; Kwon, Y.I. Molecular weight dependent glucose lowering effect of low molecular weight chitosan oligosaccharide (GO2KA1) on postprandial blood glucose level in SD rats model. Int. J. Mol. Sci. 2013, 14, 14214-14224.
16. Hanefeld, M. Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes. Cardiovasc. Diabetol. 2007, 6, 1-10.
17. Jenkins, D.J.; Taylor, R.H.; Goff, D.V.; Fielden, H.; Misiewicz, J.J.; Sarson, D.L.; Bloom, S.R.; Alberti, K.G. Scope and specificity of acarbose in slowing carbohydrate absorption in man. Diabetes 1981, 30, 951-954.
18. Matsuura, Y.; Zheng, Y.; Takaku, T.; Kameda, K.; Okuda, H. Isolation and physiological activities of a new amino acid derivative from Korean red ginseng. Korean J. Ginseng Sci. 1994, 18, 204-211.
19. Joo, K.M.; Park, C.W.; Jeng, H.J.; Lee, S.J.; Chang, I.S. Simultaneous determination of two Amadori compounds in Korean red ginseng (Panax ginseng) extracts and rat plasma by high-performance anion-exchange chromatography with pulsed amperometric detection. J. Chromatogr. B 2008, 865, 159-166.