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Volumn 14, Issue 7-8, 2011, Pages 712-717

Mulberry leaf extract reduces postprandial hyperglycemia with few side effects by inhibiting α-glucosidase in normal rats

Author keywords

a glucosidase inhibitory activity; feeding test; mulberry leaf extract; reduced side effects; sugar loading test

Indexed keywords

ACARBOSE; ALPHA GLUCOSIDASE; AMYLASE; GLUCOSE; MALTOSE; MULBERRY EXTRACT; STARCH; SUCROSE;

EID: 79960440902     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2010.1368     Document Type: Article
Times cited : (69)

References (23)
  • 2
    • 0031786344 scopus 로고    scopus 로고
    • Epidemiology and scope of the problem
    • Harris M: Epidemiology and scope of the problem. Diabetes Care 1998;21(Suppl):C11-C14.
    • (1998) Diabetes Care , vol.21 , Issue.SUPPL.
    • Harris, M.1
  • 3
    • 79960437728 scopus 로고    scopus 로고
    • Synthesis and a-d-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potent oral antidiabetic agents
    • Horii S, Fukasse K, Matsuo T, Kameda K, Asano N, Masui Y: Synthesis and a-d-glucosidase inhibitory activity of N-substituted valiolamine derivatives as potent oral antidiabetic agents. J Med Chem 2005;29:938-1046.
    • (2005) J Med Chem , vol.29 , pp. 938-1046
    • Horii, S.1    Fukasse, K.2    Matsuo, T.3    Kameda, K.4    Asano, N.5    Masui, Y.6
  • 5
    • 20044376702 scopus 로고    scopus 로고
    • The pathobiology of diabetic complications
    • Brownlee M: The pathobiology of diabetic complications. Diabetes 2005;54:1615-1625.
    • (2005) Diabetes , vol.54 , pp. 1615-1625
    • Brownlee, M.1
  • 7
    • 0017668659 scopus 로고
    • Glucosidase inhibition. A new approach to the treatment of diabetes, obesity and hyperlipoproteinaemia
    • DOI 10.1007/BF00483562
    • Puls W, Keup U, Krause HP, Thomas G, Hoffmeister R: Glu-cosidase inhibition. A new approach to the treatment of diabetes, obesity, and hyperlipoproteinaemia. Naturwissenschafen 1977; 64:536-537. (Pubitemid 8197894)
    • (1977) Naturwissenschaften , vol.64 , Issue.10 , pp. 536-537
    • Puls, W.1    Keup, U.2    Krause, H.P.3
  • 8
    • 0017845326 scopus 로고
    • Sucrose malabsorption in man after ingestion of α- glucosidehydrolase inhibitor
    • Caspary WF: Sucrose malabsorption in man after ingestion of a-glucosidehydrolase inhibitor. Lancet 1978;1:1231-1233. (Pubitemid 8362420)
    • (1978) Lancet , vol.1 , Issue.8076 , pp. 1231-1233
    • Caspary, W.F.1
  • 9
    • 0018413311 scopus 로고
    • Inhibition of human intestinal α-glucosidehydrolases by a new complex oligosaccharide
    • DOI 10.1007/BF01851228
    • Caspary WF, Graf S: Inhibition of human intestinal a-glucosi-dehydrolase by a new complex oligosaccharide. Res Exp Med 1979;175:1-6. (Pubitemid 9214738)
    • (1979) Research in Experimental Medicine , vol.175 , Issue.1 , pp. 1-6
    • Caspary, W.F.1    Graf, S.2
  • 10
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
    • DOI 10.1016/S0140-6736(02)08905-5
    • Chiasson JL, Josse RG, Gomis R: Acarbose for prevention of type 2 diabetes mellitus: the STPO-NIDDM randomised trial. Lancet 2002;359:2072-2077. (Pubitemid 34680970)
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2072-2077
    • Chiasson, J.-L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 11
    • 1642370585 scopus 로고    scopus 로고
    • Starch digestion, large-bowel fermentation and intestinal mucosal cell proliferation in rats treated with the α-glucosidase inhibitor acarbose
    • DOI 10.1079/BJN20031063
    • Dehghan-Kooshkghazi M, Mathers JC: Starch digestion, large-bowel fermentation and intestinal mucosal cell proliferation in rats treated with the a-glucosidase inhibitor acarbose. Br J Nutr 2004;91:357-365. (Pubitemid 38386899)
    • (2004) British Journal of Nutrition , vol.91 , Issue.3 , pp. 357-365
    • Dehghan-Kooshkghazi, M.1    Mathers, J.C.2
  • 12
    • 70349194909 scopus 로고    scopus 로고
    • Effects of mulberry (Morus alba L.) extracts on lipid homeostasis in vitro and in vivo
    • Liu LK, Chou FP, Chen YC, Ho HH, Wang CJ: Effects of mulberry (Morus alba L.) extracts on lipid homeostasis in vitro and in vivo. J Agric Food Chem 2009;57:7605-7611.
    • (2009) J Agric Food Chem , vol.57 , pp. 7605-7611
    • Liu, L.K.1    Chou, F.P.2    Chen, Y.C.3    Ho, H.H.4    Wang, C.J.5
  • 13
    • 70349316672 scopus 로고    scopus 로고
    • Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in strepto-zotocin-induced chronic diabetic rats
    • Naowaboot J, Pannangpetch P, Kukonqviriyapan V, Kongyin-gyoes B, Kukonqviriyapan U: Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in strepto-zotocin-induced chronic diabetic rats. Plant Foods Hum Nutr 2009;64:116-121.
    • (2009) Plant Foods Hum Nutr , vol.64 , pp. 116-121
    • Naowaboot, J.1    Pannangpetch, P.2    Kukonqviriyapan, V.3    Kongyin-Gyoes, B.4    Kukonqviriyapan, U.5
  • 14
    • 58549106859 scopus 로고    scopus 로고
    • Hypoglycemic effects of pills made of mulberry leaves and silkworm powder in streptozotocin-induced diabetic rats
    • Jang MJ, Rhee SJ: Hypoglycemic effects of pills made of mulberry leaves and silkworm powder in streptozotocin-induced diabetic rats. J Korean Soc Food Sci Nutr 2004;33:1611-1617.
    • (2004) J Korean Soc Food Sci Nutr , vol.33 , pp. 1611-1617
    • Jang, M.J.1    Rhee, S.J.2
  • 15
    • 0032851871 scopus 로고    scopus 로고
    • Hypo-glycemic effect of mulberry leaves with anaerobic treatment in alloxan-induced diabetic mice
    • Kim SY, Ryu KS, Lee WC, Ku HO, Lee HS, Lee KR: Hypo-glycemic effect of mulberry leaves with anaerobic treatment in alloxan-induced diabetic mice. Korean J Pharmacogn 1999;30: 123-129.
    • (1999) Korean J Pharmacogn , vol.30 , pp. 123-129
    • Kim, S.Y.1    Ryu, K.S.2    Lee, W.C.3    Ku, H.O.4    Lee, H.S.5    Lee, K.R.6
  • 17
    • 33644756508 scopus 로고    scopus 로고
    • Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension
    • Kwon YI, Vattem DA, Shetty K: Evaluation of clonal herbs of Lamiaceae species for management of diabetes and hypertension. Asia Pac J Clin Nutr 2006;15:107-118. (Pubitemid 43341846)
    • (2006) Asia Pacific Journal of Clinical Nutrition , vol.15 , Issue.1 , pp. 107-118
    • Kwon, Y.I.1    Vattem, D.A.2    Shetty, K.3
  • 18
    • 0036653398 scopus 로고    scopus 로고
    • α-glucosidase inhibitory activity of a 70% methanol extract from ezoishige (Pelvetia babingtonii de Toni) and its effect on the elevation of blood glucose level in rats
    • Ohta T, Sasaki S, Oohori T, Yoshikawa S, Kurihara H: a-Glucosidase inhibitory activity of a 70% methanol extract from Ezoishige (Pelvetia babingtonii de Toni) and its effect on the elevation of blood glucose level in rats. Biosci Biotechnol Bio-chem 2002;66:1552-1554. (Pubitemid 39246862)
    • (2002) Bioscience, Biotechnology and Biochemistry , vol.66 , Issue.7 , pp. 1552-1554
    • Ohta, T.1    Sasaki, S.2    Oohori, T.3    Yoshikawa, S.4    Kurihara, H.5
  • 20
    • 42649143480 scopus 로고    scopus 로고
    • Antihyperlipi-demic effects of methanol extracts from mulberry leaves in cholesterol-induced hyperlipidemia rats
    • Kim SY, Lee WC, Kim HB, Kim AJ, Kim SK: Antihyperlipi-demic effects of methanol extracts from mulberry leaves in cholesterol-induced hyperlipidemia rats. J Korean Soc Food Sci Nutr 1998;27:1217-1222.
    • (1998) J Korean Soc Food Sci Nutr , vol.27 , pp. 1217-1222
    • Kim, S.Y.1    Lee, W.C.2    Kim, H.B.3    Kim, A.J.4    Kim, S.K.5
  • 21
    • 77957708387 scopus 로고    scopus 로고
    • Varietal comparison of c-aminobutyric acid content in mulberry root bark
    • Bang HS, Lee WC, Shon HR, Choi YC, Kim HB: Varietal comparison of c-aminobutyric acid content in mulberry root bark. Korean J Seric Sci 1998;40:13-16.
    • (1998) Korean J Seric Sci , vol.40 , pp. 13-16
    • Bang, H.S.1    Lee, W.C.2    Shon, H.R.3    Choi, Y.C.4    Kim, H.B.5
  • 22
    • 79960453878 scopus 로고
    • Studies on the utilization of pharmacologically active constituents in mulberry: 1. Varietal and seasonal variations of flavonol glycoside content in leaves
    • Yun SJ, Lee WC: Studies on the utilization of pharmacologically active constituents in mulberry: 1. Varietal and seasonal variations of flavonol glycoside content in leaves. RDA J Agric Sci 1995;37:201-205.
    • (1995) RDA J Agric Sci , vol.37 , pp. 201-205
    • Yun, S.J.1    Lee, W.C.2
  • 23
    • 13444278849 scopus 로고    scopus 로고
    • A-Glucosidase inhibitionof 6-hydroxyflavones Part 3: Synthesis and evaluation of 2, 3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as a-glucosidase inhibitors
    • GaoH,KawabataJ:a-Glucosidase inhibitionof 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as a-glucosidase inhibitors. Bioorg Med Chem 2005;13:1661-1671.
    • (2005) Bioorg Med Chem , vol.13 , pp. 1661-1671
    • Gao, H.1    Kawabata, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.