Increased diverticular complications with nonsteriodal anti-inflammatory drugs and other medications: A systematic review and meta-analysis

Colorectal Disease

Volumn 16, Issue 6, 2014, Pages

  Kvasnovsky, C L ^a   Papagrigoriadis, S ^a   Bjarnason, I ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Aspirin; Diverticular perforation; NSAIDs

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; CALCIUM CHANNEL BLOCKING AGENT; CORTICOSTEROID DERIVATIVE; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE DERIVATIVE; PARACETAMOL;

ARTICLE; COCHRANE LIBRARY; COLON DIVERTICULOSIS; COLON HEMORRHAGE; DATA EXTRACTION; DATA SYNTHESIS; DISEASE SEVERITY; EMBASE; HUMAN; MEDLINE; META ANALYSIS; PRIORITY JOURNAL; QUALITY CONTROL; STUDY DESIGN; SYSTEMATIC REVIEW; CHEMICALLY INDUCED; COLON; DIVERTICULUM, COLON; GASTROINTESTINAL HEMORRHAGE; HEALTH; INTESTINAL PERFORATION; MORBIDITY; RISK FACTOR; TRENDS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COLON; DIVERTICULUM, COLON; GASTROINTESTINAL HEMORRHAGE; GLOBAL HEALTH; HUMANS; INTESTINAL PERFORATION; MORBIDITY; RISK FACTORS;

EID: 84900478687     PISSN: 14628910     EISSN: 14631318     Source Type: Journal    
DOI: 10.1111/codi.12516     Document Type: Article

References (46)

1. Kozak LJ, DeFrances CJ, Hall MJ. National hospital discharge survey: 2004 annual summary with detailed diagnosis and procedure data. Vital Health Stat 2006; 13: 1-209.
2. Shahedi K, Fuller G, Bolus R et al. Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clin Gastroenterol Hepatol 2013; 11: 1609-13.
3. Humes DJ, Solaymani-Dodaran M, Fleming KM et al. A population-based study of perforated diverticular disease incidence and associated mortality. Gastroenterology 2009; 136: 1198-205.
4. Zeitoun G, Laurent A, Rouffet F et al. Multicentre, randomized trial of primary versus secondary sigmoid resection in generalized peritonitis complicating sigmoid diverticulitis. Br J Surg 2000; 87: 1366-74.
5. Strate LL. Lifestyle factors and the course of diverticular disease. Dig Dis 2012; 30: 35-45.
6. Simpson J, Scholefield JH, Spiller RC. Pathogenesis of colonic diverticula. Br J Surg 2002; 89: 546-54.
7. Moher D, Liberati A, Tetzlaff J et al. for PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009; 62: 1006-12.
8. Hwang SS, Cannom RR, Abbas MA et al. Diverticulitis in transplant patients and patients on chronic corticosteroid therapy: a systematic review. Dis Colon Rectum 2010; 53: 1699-707.
9. Curtis JR, Xie F, Chen L et al. The incidence of ga+trointestinal perforations among rheumatoid arthritis patients. Arthritis Rheum 2011; 63: 346-51.
10. Vandenbrouke JP, von Elm E, Altman DG et al. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Ann Intern Med 2007; 147: W163-94.
11. Corder A. Steroids, non-steroidal anti-inflammatory drugs, and serious septic complications of diverticular disease. Br Med J (Clin Res Ed) 1987; 295: 1238.
12. Finkelstein JA, Jamieson CG. An association between anti-inflammatory medication and internal pelvic fistulas. Dis Colon Rectum 1987; 30: 168-70.
13. Jansen A, Harenberg S, Grenda U et al. Risk factors for colonic diverticular bleeding: a Westernized community based hospital study. World J Gastroenterol 2009; 15: 457-61.
14. Niikura R, Nagata N, Akiyama J et al. Hypertension and concomitant arteriosclerotic diseases are risk factors for colonic diverticular bleeding: a case-control study. Int J Colorectal Dis 2012; 27: 1137-43.
15. Suzuki K, Uchiyama S, Imajyo K et al. Risk factors for colonic diverticular hemorrhage: Japanese multicenter study. Digestion 2012; 85: 261-5.
16. Wilson RG, Smith AN, Macintyre IM. Complications of diverticular disease and non-steroidal anti-inflammatory drugs: a prospective study. Br J Surg 1990; 77: 1103-4.
17. Dean AG, Sullivan KM, Soe MM. OpenEpi: Open Source Epidemiologic Statistics for Public Health, Version 2.3.1. http://www.OpenEpi.com, updated 2011/23/06 (accessed October 2012).
18. Sterne JAC, Egger M, Moher D (editors). Chapter 10: adressing reporting biases. In: Cochrane Handbook for Systematic Reviews of Interventions. Version 5.0.1 [updated September 2008]. (eds Higgins JPT, Green S). Sussex, UK: The Cochrane Collaboration, 2007. http://www.cochrane-handbook.org (accessed December 2012)
19. Tsuruoka N, Iwakiri R, Hara M et al. NSAIDs are a significant risk factor for colonic diverticular hemorrhage in elder patients: evaluation by a case-control study. J Gastroenterol Hepatol 2011; 26: 1047-52.
20. Morris CR, Harvey IM, Stebbings WS et al. Do calcium channel blockers and antimuscarinics protect against perforated colonic diverticular disease? A case control study Gut 2003; 52: 1734-7.
21. Strate LL, Liu YL, Huang ES et al. Use of aspirin or nonsteroidal anti-inflammatory drugs increases risk for diverticulitis and diverticular bleeding. Gastroenterology 2011; 140: 1427-33.
22. Humes DJ, Fleming KM, Spiller RC et al. Concurrent drug use and the risk of perforated colonic diverticular disease: a population-based case-control study. Gut 2011; 60: 219-24.
23. Campbell K, Steele RJC. Non-steroidal anti-inflammatory drugs and complicated diverticular disease: a case-control study. Br J Surg 1991; 78: 190-1.
24. de Boer SY, Stolk MF, van Berge Henegouwen GP, Eggink WF. Non-steroidal ant-inflammatory drugs and inflammation of the colon. Ned Tijdschr Geneeskd 1989; 133: 883-6.
25. Goh H, Bourne R. Non-steroidal anti-inflammatory drugs and perforated diverticular disease: a case-control study. Ann R Coll Surg Engl 2002; 84: 93-6.
26. Morris CR, Harvey IM, Stebbings WS et al. Anti-inflammatory drugs, analgesics and the risk of perforated colonic diverticular disease. Br J Surg 2003; 90: 1267-72.
27. Mpofu S, Mpofu CM, Hutchinson D et al. Steroids, non-steroidal anti-inflammatory drugs, and sigmoid diverticular abscess perforation in rheumatic conditions. Ann Rheum Dis 2004; 63: 588-90.
28. Piekarek K, Israelsson LA. Perforated colonic diverticular disease: the importance of NSAIDs, opioids, corticosteroids, and calcium channel blockers. Int J Colorectal Dis 2008; 23: 1193-7.
29. Aldoori WH, Giovannucci EL, Rimm EB et al. Use of acetaminophen and nonsteroidal anti-inflammatory drugs: a prospective study and the risk of symptomatic diverticular disease in men. Arch Fam Med 1998; 7: 255-60.
30. Chang CH, Lin JW, Chen HC et al. Non-steroidal anti-inflammatory drugs and risk of lower gastrointestinal adverse events: a nationwide study in Taiwan. Gut 2011; 60: 1372-8.
31. Lee KK, Shah SM, Moser MA. Risk factors predictive of severe diverticular hemorrhage. Int J Surg 2011; 9: 83-5.
32. Okamoto T, Watabe H, Yamada A et al. The association between arteriosclerosis related diseases and diverticular bleeding. Int J Colorectal Dis 2012; 27: 1161-6.
33. Suh S, Seo PJ, Park H et al. The risk factors for colonic diverticular bleeding. Korean J Gastroenterol 2012; 60: 349-54.
34. Wilcox CM, Alexander LN, Cotsonis GA et al. Nonsteroidal antiinflammatory drugs are associated with both upper and lower gastrointestinal bleeding. Dig Dis Sci 1997; 42: 990-7.
35. Yamada A, Sugimoto T, Kondo S et al. Assessment of the risk factors for colonic diverticular hemorrhage. Dis Colon Rectum 2008; 51: 116-20.
36. Lau J, Ionnadis JP, Terrin N, Scmid CH, Olkin I. The case of the misleading funnel plot. BMJ 2006; 333: 597-600.
37. Matteson KA, Anderson BL, Pinto SB, Lopes V, Schulkin J, Clark MA. Surveying ourselves: examining the use of a web-based approach for a physician survey. Eval Health Prof 2011; 34: 448-63.
38. De Berardis G, Lucisano G, D'Ettorre A et al. Association of aspirin use with major bleeding in patients with and without diabetes. JAMA 2012; 307: 2286-94.
39. Metz SA. Anti-inflammatory agents as inhibitors of prostaglandin synthesis in man. Med Clin North Am 1981; 65: 713-57.
40. JR Vane. The mode of action of aspirin and similar compounds. J Allergy Clin Immunol 1976; 58: 691-72.
41. Wolfe MM, Lichtenstein DR, Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 1999; 340: 1888-99.
42. Hernández-Díaz S, Rodríguez LA. Association between nonsteroidal anti-inflammatory drugs and upper gastrointestinal tract bleeding/perforation: an overview of epidemiologic studies published in the 1990s. Arch Intern Med 2000; 160: 2093-9.
43. MacDonald TM, Morant SV, Robinson GC et al. Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study. BMJ 1997; 315: 1333-7.
44. Scholz S. Pharmacological aspects of calcium channel blockers. Cardiovasc Drugs Ther 1997; 10: 869-72.
45. Chappuis CW, Cohn I. Acute colonic diverticulitis. Surg Clin North Am 1988; 68: 301-12.
46. Niikura R, Nagata N, Yamada A et al. Recurrence of colonic diverticular bleeding and associated risk factors. Colorectal Dis 2011; 13: 302-5.