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Volumn 9, Issue , 2014, Pages 469-479

Comparative efficacy of inhaled corticosteroid and long-acting beta agonist combinations in preventing COPD exacerbations: A bayesian network meta-analysis

Author keywords

Combination therapy

Indexed keywords

BECLOMETASONE DIPROPIONATE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; CORTICOSTEROID; FLUTICASONE FUROATE; FLUTICASONE PROPIONATE; FORMOTEROL; LONG ACTING DRUG; MOMETASONE FUROATE; OXYGEN; PLACEBO; SALMETEROL; VILANTEROL;

EID: 84900461669     PISSN: 11769106     EISSN: 11782005     Source Type: Journal    
DOI: 10.2147/COPD.S48492     Document Type: Article
Times cited : (25)

References (32)
  • 1
    • 60849134196 scopus 로고    scopus 로고
    • World Health Organization, Available from, Accessed April 28, 2014
    • World Health Organization. Global Alliance Against Chronic Respiratory Diseases. 2008. Available from: http://www.who.int/gard/publications/Istanbul_report_final.pdf. Accessed April 28, 2014.
    • (2008) Global Alliance Against Chronic Respiratory Diseases
  • 2
    • 24044503638 scopus 로고    scopus 로고
    • US Department of Health and Human Services, CDC, National Center for Health Statistics. National Vital Statistics Reports; 2011. Available from, Accessed February 14, 2014
    • Kochanek KD, Xu J, Murphy SL, Miniño AM, Kung HC. Deaths: Preliminary Data for 2009. US Department of Health and Human Services, CDC, National Center for Health Statistics. National Vital Statistics Reports; 2011. Available from: http://www.cdc.gov/nchs/data/nvsr/nvsr59/nvsr59_04.pdf. Accessed February 14, 2014.
    • Deaths: Preliminary Data For 2009
    • Kochanek, K.D.1    Xu, J.2    Murphy, S.L.3    Miniño, A.M.4    Kung, H.C.5
  • 4
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Vestbo J, Hurd SS, Agustí AG, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013;187(4): 347-365.
    • (2013) Am J Respir Crit Care Med , vol.187 , Issue.4 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agustí, A.G.3
  • 5
    • 33847172367 scopus 로고    scopus 로고
    • TORCH Investigators. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
    • Calverley PM, Anderson JA, Celli B, et al; TORCH Investigators. Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med. 2007;356(8):775-789.
    • (2007) N Engl J Med , vol.356 , Issue.8 , pp. 775-789
    • Calverley, P.M.1    Anderson, J.A.2    Celli, B.3
  • 6
    • 84872712827 scopus 로고    scopus 로고
    • Pharmaceutical approval update
    • Goldenberg MM. Pharmaceutical approval update. P T. 2013;38(7): 389-403.
    • (2013) P T , vol.38 , Issue.7 , pp. 389-403
    • Goldenberg, M.M.1
  • 7
    • 5044221416 scopus 로고    scopus 로고
    • Combination of direct and indirect evidence in mixed treatment comparisons
    • Lu G, Ades AE. Combination of direct and indirect evidence in mixed treatment comparisons. Stat Med. 2004;23(20):3105-3124.
    • (2004) Stat Med , vol.23 , Issue.20 , pp. 3105-3124
    • Lu, G.1    Ades, A.E.2
  • 8
    • 52649100566 scopus 로고    scopus 로고
    • Bayesian meta-analysis of multiple treatment comparisons: An introduction to mixed treatment comparisons
    • Jansen JP, Crawford B, Bergman G, Stam W. Bayesian meta-analysis of multiple treatment comparisons: an introduction to mixed treatment comparisons. Value Health. 2008;11(5):956-964.
    • (2008) Value Health , vol.11 , Issue.5 , pp. 956-964
    • Jansen, J.P.1    Crawford, B.2    Bergman, G.3    Stam, W.4
  • 9
    • 33847413080 scopus 로고    scopus 로고
    • Assessing the convergence of Markov Chain Monte Carlo methods: An example from evaluation of diagnostic tests in absence of a gold standard
    • Toft N, Innocent GT, Gettinby G, Reid SW. Assessing the convergence of Markov Chain Monte Carlo methods: an example from evaluation of diagnostic tests in absence of a gold standard. Prev Vet Med. 2007;79(2-4):244-256.
    • (2007) Prev Vet Med , vol.79 , Issue.2-4 , pp. 244-256
    • Toft, N.1    Innocent, G.T.2    Gettinby, G.3    Reid, S.W.4
  • 10
    • 4844226835 scopus 로고    scopus 로고
    • Meta-analytic methods for pooling rates when follow-up duration varies: A case study
    • Guevara JP, Berlin JA, Wolf FM. Meta-analytic methods for pooling rates when follow-up duration varies: a case study. BMC Med Res Methodol. 2004;4:17.
    • (2004) BMC Med Res Methodol , vol.4 , pp. 17
    • Guevara, J.P.1    Berlin, J.A.2    Wolf, F.M.3
  • 12
    • 85067757032 scopus 로고    scopus 로고
    • Fluticasone Propionate Combination Product 25/250 μg Two Puffs Bd and Fluticasone Propionate 250 μg Two Puffs Bd Alone, All Administered Via Metered Dose Inhalers (MDI), In the Treatment of Subjects With Chronic Obstructive Pulmonary Disease (COPD) For 52 Weeks Available from, Accessed February 17, 2014
    • Glaxo Smith Kline. A Multicentre, Randomised, Double-Blind, Parallel Group, Placebo-Controlled Study to Compare the Efficacy and Safety of Inhaled Salmeterol/Fluticasone Propionate Combination Product 25/250 μg Two Puffs bd and Fluticasone Propionate 250 μg Two Puffs bd Alone, All Administered Via Metered Dose Inhalers (MDI), in the Treatment of Subjects with Chronic Obstructive Pulmonary Disease (COPD) for 52 Weeks; 2005. Available from: http://www.gsk-clinicalstudyregister.com/files2/23674.pdf. Accessed February 17, 2014.
    • (2005) A Multicentre, Randomised, Double-Blind, Parallel Group, Placebo-Controlled Study to Compare the Efficacy and Safety of Inhaled Salmeterol
    • Kline, G.S.1
  • 13
    • 85067767898 scopus 로고    scopus 로고
    • A phase III, 12-week, double-blind, randomised, parallel-group, active controlled, multinational, efficacy and safety study of Symbicort® Turbuhaler® 160/4.5 μg 2 inhalations twice daily (bid) compared to Oxis® Turbuhaler® 4.5 μg 2 inhalations twice daily (bid) in patients with chronic obstructive pulmonary disease [webpage on the Internet]. Washington, DC: National Institutes of Health; 2010 [updated Sep 2012]. Available from, Accessed February 17, 2014
    • Astra Zeneca. A phase III, 12-week, double-blind, randomised, parallel-group, active controlled, multinational, efficacy and safety study of Symbicort® Turbuhaler® 160/4.5 μg 2 inhalations twice daily (bid) compared to Oxis® Turbuhaler® 4.5 μg 2 inhalations twice daily (bid) in patients with chronic obstructive pulmonary disease [webpage on the Internet]. Washington, DC: National Institutes of Health; 2010 [updated Sep 2012]. Available from: http://clinicaltrials.gov/ct2/show/study/NCT01069289. Accessed February 17, 2014.
    • Zeneca, A.1
  • 14
    • 84877126115 scopus 로고    scopus 로고
    • Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: Two replicate double-blind, parallel-group, randomised controlled trials
    • Dransfield MT, Bourbeau J, Jones PW, et al. Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir Med. 2013;1(3):210-223.
    • (2013) Lancet Respir Med , vol.1 , Issue.3 , pp. 210-223
    • Dransfield, M.T.1    Bourbeau, J.2    Jones, P.W.3
  • 15
    • 0037108632 scopus 로고    scopus 로고
    • Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease
    • Mahler DA, Wire P, Horstman D, et al. Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2002;166(8):1084-1091.
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.8 , pp. 1084-1091
    • Mahler, D.A.1    Wire, P.2    Horstman, D.3
  • 16
    • 0037425745 scopus 로고    scopus 로고
    • Trial of Inhaled STeroids ANd long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: A randomised controlled trial
    • Calverley P, Pauwels R, Vestbo J, et al; Trial of Inhaled STeroids ANd long-acting beta2 agonists study group. Combined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trial. Lancet. 2003;361(9356):449-456.
    • (2003) Lancet , vol.361 , Issue.9356 , pp. 449-456
    • Calverley, P.1    Pauwels, R.2    Vestbo, J.3
  • 17
    • 0347473812 scopus 로고    scopus 로고
    • Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
    • Calverley PM, Boonsawat W, Cseke Z, Zhong N, Peterson S, Olsson H. Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease. Eur Respir J. 2003;22(6):912-919.
    • (2003) Eur Respir J , vol.22 , Issue.6 , pp. 912-919
    • Calverley, P.M.1    Boonsawat, W.2    Cseke, Z.3    Zhong, N.4    Peterson, S.5    Olsson, H.6
  • 18
    • 0141558800 scopus 로고    scopus 로고
    • The efficacy and safety of fluticasone propionate (250 microg)/salmeterol (50 microg) combined in the Diskus inhaler for the treatment of COPD
    • Hanania NA, Darken P, Horstman D, et al. The efficacy and safety of fluticasone propionate (250 microg)/salmeterol (50 microg) combined in the Diskus inhaler for the treatment of COPD. Chest. 2003;124(3): 834-843.
    • (2003) Chest , vol.124 , Issue.3 , pp. 834-843
    • Hanania, N.A.1    Darken, P.2    Horstman, D.3
  • 19
    • 0037246566 scopus 로고    scopus 로고
    • Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease
    • Szafranski W, Cukier A, Ramirez A, et al. Efficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary disease. Eur Respir J. 2003;21(1):74-81.
    • (2003) Eur Respir J , vol.21 , Issue.1 , pp. 74-81
    • Szafranski, W.1    Cukier, A.2    Ramirez, A.3
  • 20
    • 33846318149 scopus 로고    scopus 로고
    • Impact of salmeterol/fluticasone propionate versus salmeterol on exacerbations in severe chronic obstructive pulmonary disease
    • Kardos P, Wencker M, Glaab T, Vogelmeier C. Impact of salmeterol/fluticasone propionate versus salmeterol on exacerbations in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007;175(2):144-149.
    • (2007) Am J Respir Crit Care Med , vol.175 , Issue.2 , pp. 144-149
    • Kardos, P.1    Wencker, M.2    Glaab, T.3    Vogelmeier, C.4
  • 21
    • 37549070319 scopus 로고    scopus 로고
    • The efficacy and safety of combination salmeterol (50 microg)/fluticasone propionate (500 microg) inhalation twice daily via accuhaler in Chinese patients with COPD
    • Zheng JP, Yang L, Wu YM, et al. The efficacy and safety of combination salmeterol (50 microg)/fluticasone propionate (500 microg) inhalation twice daily via accuhaler in Chinese patients with COPD. Chest. 2007;132(6):1756-1763.
    • (2007) Chest , vol.132 , Issue.6 , pp. 1756-1763
    • Zheng, J.P.1    Yang, L.2    Wu, Y.M.3
  • 22
    • 47249103757 scopus 로고    scopus 로고
    • Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations
    • Ferguson GT, Anzueto A, Fei R, Emmett A, Knobil K, Kalberg C. Effect of fluticasone propionate/salmeterol (250/50 microg) or salmeterol (50 microg) on COPD exacerbations. Respir Med. 2008;102(8): 1099-1108.
    • (2008) Respir Med , vol.102 , Issue.8 , pp. 1099-1108
    • Ferguson, G.T.1    Anzueto, A.2    Fei, R.3    Emmett, A.4    Knobil, K.5    Kalberg, C.6
  • 23
    • 51449109607 scopus 로고    scopus 로고
    • Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: Results of a 6-month randomized clinical trial
    • Tashkin DP, Rennard SI, Martin P, et al. Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial. Drugs. 2008;68(14): 1975-2000.
    • (2008) Drugs , vol.68 , Issue.14 , pp. 1975-2000
    • Tashkin, D.P.1    Rennard, S.I.2    Martin, P.3
  • 24
    • 70350112427 scopus 로고    scopus 로고
    • Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes
    • Anzueto A, Ferguson GT, Feldman G, et al. Effect of fluticasone propionate/salmeterol (250/50) on COPD exacerbations and impact on patient outcomes. COPD. 2009;6(5):320-329.
    • (2009) COPD , vol.6 , Issue.5 , pp. 320-329
    • Anzueto, A.1    Ferguson, G.T.2    Feldman, G.3
  • 25
    • 64949164160 scopus 로고    scopus 로고
    • Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: Results from a 1-year randomized controlled clinical trial
    • Rennard SI, Tashkin DP, McElhattan J, et al. Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial. Drugs. 2009;69(5):549-565.
    • (2009) Drugs , vol.69 , Issue.5 , pp. 549-565
    • Rennard, S.I.1    Tashkin, D.P.2    McElhattan, J.3
  • 26
    • 78650026603 scopus 로고    scopus 로고
    • Beclomethasone/formoterol in the management of COPD: A randomised controlled trial
    • Calverley PM, Kuna P, Monsó E, et al. Beclomethasone/formoterol in the management of COPD: a randomised controlled trial. Respir Med. 2010;104(12):1858-1868.
    • (2010) Respir Med , vol.104 , Issue.12 , pp. 1858-1868
    • Calverley, P.M.1    Kuna, P.2    Monsó, E.3
  • 27
    • 84655165038 scopus 로고    scopus 로고
    • Effect of budesonide/formoterol pMDI on COPD exacerbations: A double-blind, randomized study
    • Sharafkhaneh A, Southard JG, Goldman M, Uryniak T, Martin UJ. Effect of budesonide/formoterol pMDI on COPD exacerbations: a double-blind, randomized study. Respir Med. 2012;106(2):257-268.
    • (2012) Respir Med , vol.106 , Issue.2 , pp. 257-268
    • Sharafkhaneh, A.1    Southard, J.G.2    Goldman, M.3    Uryniak, T.4    Martin, U.J.5
  • 28
    • 84857087260 scopus 로고    scopus 로고
    • Efficacy and safety characteristics of mometasone furoate/formoterol fumarate fixed-dose combination in subjects with moderate to very severe COPD: Findings from pooled analysis of two randomized, 52-week placebo-controlled trials
    • Tashkin DP, Doherty DE, Kerwin E, et al. Efficacy and safety characteristics of mometasone furoate/formoterol fumarate fixed-dose combination in subjects with moderate to very severe COPD: findings from pooled analysis of two randomized, 52-week placebo-controlled trials. Int J Chron Obstruct Pulmon Dis. 2012;7:73-86.
    • (2012) Int J Chron Obstruct Pulmon Dis , vol.7 , pp. 73-86
    • Tashkin, D.P.1    Doherty, D.E.2    Kerwin, E.3
  • 29
    • 84863033828 scopus 로고    scopus 로고
    • Efficacy and safety of budesonide/formoterol via a dry powder inhaler in Chinese patients with chronic obstructive pulmonary disease
    • Zhong N, Zheng J, Wen F, et al. Efficacy and safety of budesonide/formoterol via a dry powder inhaler in Chinese patients with chronic obstructive pulmonary disease. Curr Med Res Opin. 2012;28(2): 257-265.
    • (2012) Curr Med Res Opin , vol.28 , Issue.2 , pp. 257-265
    • Zhong, N.1    Zheng, J.2    Wen, F.3
  • 30
    • 84875236353 scopus 로고    scopus 로고
    • Fluticasone furoate/vilanterol (100/25; 200/25 μg) improves lung function in COPD: A randomised trial
    • Martinez FJ, Boscia J, Feldman G, et al. Fluticasone furoate/vilanterol (100/25; 200/25 μg) improves lung function in COPD: a randomised trial. Respir Med. 2013;107(4):550-559.
    • (2013) Respir Med , vol.107 , Issue.4 , pp. 550-559
    • Martinez, F.J.1    Boscia, J.2    Feldman, G.3
  • 31
    • 84875257111 scopus 로고    scopus 로고
    • A randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPD
    • Kerwin EM, Scott-Wilson C, Sanford L, et al. A randomised trial of fluticasone furoate/vilanterol (50/25 μg; 100/25 μg) on lung function in COPD. Respir Med. 2013;107(4):560-569.
    • (2013) Respir Med , vol.107 , Issue.4 , pp. 560-569
    • Kerwin, E.M.1    Scott-Wilson, C.2    Sanford, L.3
  • 32
    • 40949119305 scopus 로고    scopus 로고
    • Combined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease
    • Nannini LJ, Poole P, Milan SJ, Holmes R, Normansell R. Combined corticosteroid and long-acting beta2-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2013;11:CD003794.
    • (2013) Cochrane Database Syst Rev , vol.11
    • Nannini, L.J.1    Poole, P.2    Milan, S.J.3    Holmes, R.4    Normansell, R.5


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