Radiotherapy- or radical surgery-induced female sexual morbidity in stages IB and II cervical cancer

International Journal of Gynecological Cancer

Volumn 24, Issue 4, 2014, Pages 800-805

  Harding, Yuko ^a   Ooyama, Takuma ^a   Nakamoto, Tomoko ^a   Wakayama, Akihiko ^a   Kudaka, Wataru ^a   Inamine, Morihiko ^a   Nagai, Yutaka ^a   Ueda, Shinichiro ^a   Aoki, Yoichi ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Cervical cancer; Female sexual dysfunction; Radical surgery; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT;

ABDOMINAL HYSTERECTOMY; ABDOMINAL SURGERY; ABDOMINAL TRACHELECTOMY; ADULT; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVOR; CHEMORADIOTHERAPY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DYSPAREUNIA; FEMALE; FEMALE SEXUAL DYSFUNCTION; FEMALE SEXUAL FUNCTION INDEX; GYNECOLOGIC SURGERY; HUMAN; MAJOR CLINICAL STUDY; MORBIDITY; OBSERVATIONAL STUDY; ORGASM; OUTCOME ASSESSMENT; PATIENT COUNSELING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUESTIONNAIRE; REHABILITATION CARE; SELF REPORT; SEXUAL AROUSAL; SEXUAL BEHAVIOR; SEXUAL DESIRE; SEXUAL FUNCTION; SEXUAL SATISFACTION; UTERINE CERVIX CANCER; VAGINAL LUBRICATION; CASE CONTROL STUDY; COMPARATIVE STUDY; COMPLICATION; FOLLOW UP; HYSTERECTOMY; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PROGNOSIS; RADIOTHERAPY; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; SEXUALITY; STATISTICS AND NUMERICAL DATA; UTERINE CERVICAL NEOPLASMS; WOMEN'S HEALTH;

ADULT; AGED; CASE-CONTROL STUDIES; COMBINED MODALITY THERAPY; CROSS-SECTIONAL STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYSTERECTOMY; MIDDLE AGED; MORBIDITY; NEOPLASM STAGING; PROGNOSIS; QUESTIONNAIRES; RADIOTHERAPY; SEXUAL DYSFUNCTION, PHYSIOLOGICAL; SEXUALITY; UTERINE CERVICAL NEOPLASMS; WOMEN'S HEALTH;

EID: 84900454814     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0000000000000112     Document Type: Article

References (25)

1. Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010;127:2893-2917
2. Landoni F, Maneo A, Colombo A, et al. Randomised study of radical surgery versus radiotherapy for stage IB-IIA cervical cancer. Lancet. 1997;350:535-540.
3. Donovan KA, Taliaferro LA, Alvarez EM, et al. Sexual health in women treated for cervical cancer: characteristics and correlates. Gynecol Oncol. 2007;104:428-434.
4. Bergmark K, Avall-Lundqvist E, Dickman PW, et al. Vaginal changes and sexuality in women with a history of cervical cancer. N Engl J Med. 1999;340:1383-1389.
5. Pauls RN, Kleeman SD, Karram MM. Female sexual dysfunction: principles of diagnosis and therapy. Obstet Gynecol Surv. 2005;60:196-205.
6. Hsu WC, Chung NN, Chen YC, et al. Comparison of surgery or radiotherapy on complications and quality of life in patients with the stage IB and IIA uterine cervical cancer. Gynecol Oncol. 2009;115:41-45.
7. Abitbol MM, Davenport JH. Sexual dysfunction after therapy for cervical carcinoma. Am J Obstet Gynecol. 1974;119: 181-189.
8. Schover LR. Sexuality and fertility after cancer. Hematol Am Soc Hematol Educ Program. 2005:523-527.
9. Jensen PT, Groenvold M, Klee MC, et al. Longitudinal study of sexual function and vaginal changes after radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys. 2003;56:937-949.
10. Flay LD, Matthews JH. The effects of radiotherapy and surgery on the sexual function of women treated for cervical cancer. Int J Radiat Oncol Biol Phys. 1995;31:399-404.
11. Denton AS, Maher EJ. Interventions for the physical aspects of sexual dysfunction in women following pelvic radiotherapy. Cochrane Database Syst Rev. 2003:CD003750.
12. Lammerink EA, de Bock GH, Pras E, et al. Sexual functioning of cervical cancer survivors: a review with a female perspective. Maturitas. 2012;72:296-304.
13. Ohkawa R, Takamizawa H, Arai T, et al. Female sexual dysfunction after radiotherapy for uterine cancer [in Japanese]. Obstet Gynecol Ther. 1981;42:257-263.
14. Rosen R, Brown C, Heiman J, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26:191-208.
15. Fujii S. Original film of the Okabayashi's radical hysterectomy by Okabayashi himself in 1932, and two films of the precise anatomy necessary for nerve-sparing Okabayashi's radical hysterectomy clarified by Shingo Fujii. Int J Gynecol Cancer. 2008;18:383-385.
16. Meston CM. Validation of the Female Sexual Function Index (FSFI) in women with female orgasmic disorder and in women with hypoactive sexual desire disorder. J Sex Marital Ther. 2003;29:39-46.
17. Frumovitz M, Sun CC, Schover LR, et al. Quality of life and sexual functioning in cervical cancer survivors. J Clin Oncol. 2005;23:7428-7436.
18. Rodrigues AC, Teixeira R, Teixeira T, et al. Impact of pelvic radiotherapy on female sexuality. Arch Gynecol Obstet. 2012;285:505-514.
19. Park SY, Bae DS, Nam JH, et al. Quality of life and sexual problems in disease-free survivors of cervical cancer compared with the general population. Cancer. 2007;110:2716-2725.
20. Cull A, Cowie VJ, Farquharson DI, et al. Early stage cervical cancer: psychosocial and sexual outcomes of treatment. Br J Cancer. 1993;68:1216-1220.
21. Hisasue S, Kumamoto Y, Sato Y, et al. Prevalence of female sexual dysfunction symptoms and its relationship to quality of life: a Japanese female cohort study. Urology. 2005;65:143-148.
22. Takahashi M, Inokuchi T,Watanabe C, et al. The Female Sexual Function Index (FSFI): development of a Japanese version. J Sex Med. 2011;8:2246-2254.
23. Katz A. Interventions for sexuality after pelvic radiation therapy and gynecological cancer. Cancer J. 2009;15:45-47.
24. Robinson JW, Faris PD, Scott CB. Psychoeducational group increases vaginal dilation for younger women and reduces sexual fears for women of all ages with gynecological carcinoma treated with radiotherapy. Int J Radiat Oncol Biol Phys. 1999;44:497-506.
25. White ID. The assessment and management of sexual difficulties after treatment of cervical and endometrial malignancies. Clin Oncol (R Coll Radiol). 2008;20:488-496.