TMEM16A protein attenuates lipopolysaccharide-mediated inflammatory response of human lung epithelial cell line A549

Experimental Lung Research

Volumn 40, Issue 5, 2014, Pages 237-250

  Zhang, Aili ^a,b   Yan, Xixin ^a   Li, Honglin ^a   Gu, Zhenfang ^c   Zhang, Peng ^d   Zhang, Hailin ^a   Li, Yangyang ^a   Yu, Hongmin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI GENERAL HOSPITAL   (China)

^c Third Hospital of Shijiazhuang   (China)

^d TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acute respiratory distress syndrome; Alveolar epithelial cell; Calcium activated chloride channels; IL 8; Proinflammatory cytokine; TNF

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LENTIVIRUS VECTOR; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN TMEM16A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANO1 PROTEIN, RAT; CHLORIDE CHANNEL; CYTOKINE;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CYTOKINE RELEASE; EPITHELIUM CELL; GENE OVEREXPRESSION; GENE SILENCING; INFLAMMATION; LUCIFERASE ASSAY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; GENETICS; HUMAN; IMMUNOLOGY; LUNG; MALE; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CELLS, CULTURED; CHLORIDE CHANNELS; CYTOKINES; EPITHELIAL CELLS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; MALE; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE;

EID: 84900443515     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.3109/01902148.2014.905655     Document Type: Article

References (37)

1. Peter JV, John P, Graham PL, Moran JL, George IA, Bersten A: Corticosteroids in the prevention and treatment of acute respiratory distress syndrome (ARDS) in adults:meta-analysis. BMJ. 2008;336(7651):1006-1009.
2. Wheeler AP, Bernard GR: Acute lung injury and the acute respiratory distress syndrome: A clinical review. Lancet. 2007;369(9572):1553-1564.
3. Martin TR, Hagimoto N, Nakamura M, Matute-Bello G: Apoptosis and epithelial injury in the lungs. Proc Am Thorac Soc. 2005;2(3):214-220.
4. Perl M, Lomas-Neira J, Chung CS, Ayala A: Epithelial cell apoptosis and neutrophil recruitment in acute lung injury-A unifying hypothesis What we have learned from small interfering RNAs. Mol Med. 2008;14(7-8):465-475.
5. Tang PS, Mura M, Seth R, Liu M: Acute lung injury and cell death: How many ways can cells die Am J Physiol Lung Cell Mol Physiol. 2008;294(4):L632- L641.
6. Wissel H, S chulz C, Koehne P, Richter E, Maass M, Rudiger M: Chlamydophila pneumoniae induces expression of tolllike receptor 4 and release of TNF-alpha and MIP-2 via an NF-kappaB pathway in rat type II pneumocytes. Respir Res. 2005;6:51.
7. Feng T, Yunfeng N, Jinbo Z, Zhipei Z, Huizhong Z, Li L, Tao J, Yunjie W: Single immunoglobulin IL-1 receptorrelated protein attenuates the lipopolysaccharide-induced inflammatory res ponse in A549 cells. Chem Biol Interact. 2010;183(3):442-449.
8. MendezMP, Morris SB, Wilcoxen S, Du M, Monroy YK, Remmer H, Murphy H, Christensen PJ, Paine R 3rd: Disparate mec hanisms of sICAM-1 production in the peripheral lung: Contrast between alveolar epithelial cells and pulmonary microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2008;294(4):L807-L814.
9. Caputo A, Caci E, Ferrera L, Pedemonte N, Barsanti C, Sondo E, Pfeffer U, Ravazzolo R, Zegarra-Moran O, Galietta LJ: TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity. Science. 2008;322(5901):590-594.
10. Dutta AK, Khimji AK, Kresge C, Bugde A, Dougherty M, Esser V, Ueno Y, Glaser SS, Alpini G, Rockey DC, Feranchak AP: Identification and functional characterization of TMEM16A, a Ca2+-activated Cl-channel activated by extracellular nucleotides, in biliary epithelium. J Biol Chem. 2011;286(1):766-776.
11. Huang F, Rock J R, Harfe BD, Cheng T, Huang X, Jan YN, Jan LY: Studies on expression and function of the TMEM16A calcium-activated chloride channel. Proc Natl Acad Sci USA. 2009;106(50):21413-21418.
12. Hwang SJ, Blair PJ, Britton FC, ODriscoll KE, Hennig G, Bayguinov YR, Rock JR, Harfe BD, Sanders KM, Ward SM: Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave acti vity in gastrointestinal muscles. J Physiol. 2009;587(Pt 20):4887-4904.
13. Romanenko VG, Catalan MA, Brown DA, Putzier I, Hartzell HC,Marmorstein AD,Gonzalez-Begne M, Rock JR,Harfe BD, M elvin JE: Tmem16A encodes the Ca2+-activated Cl-channel in mouse submandibular salivary gland acinar cells. J Biol Chem. 2010;285(17):12990-13001.
14. Schroeder BC, Cheng T, Jan YN, Jan LY: Expression cloning of TMEM16A as a calcium-activated chloride channel subunit. Cell. 2008;134(6):1019-1029.
15. Xiao Q, Yu K, Perez-Cornejo P, Cui Y, Arreola J, Hartzell HC: Volta ge-and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop. Proc Natl Acad Sci USA. 2011;108(21):8891-8896.
16. Yang YD, Cho H, Koo JY, TakMH, Cho Y, ShimWS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U: TMEM16A confers receptor-activated calcium-dependent chloride conductance. Nature. 2008;455(7217):1210-1215.
17. Ousingsawat J, Martins JR, Schreiber R, Rock JR, Harfe BD, Kunzelmann K: Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem. 2009;284(42):28698-28 703.
18. Rock JR, Futtner CR, Harfe BD: The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008;321(1):141-149.
19. Ro ck JR, ONeal WK, Gabriel SE, Randell SH, Harfe BD, Boucher RC, Grubb BR: Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl-secretory channel in mouse airways. J Biol Chem. 2009;284(22):14875-14880.
20. Tarran R, Button B, Boucher RC: Regulation of normal and cystic fibrosis airway surface liquid volume by phasic shear stress. Ann Rev Physiol. 2006;68:543-561.
21. Garcia MA, Yang N, Quinton PM: Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulatordependent bicarbonate secretion. J Clin Invest. 2009;119(9): 2613-2622.
22. Gerson C, Sabater J, Scuri M, Torbati A, Coffey R, Abraham JW, Lauredo I, Forteza R, Wanner A, Salathe M, Abraham WM, Conner GE: The lactoperoxidase system functions in bacterial clearance of airways. Am J Respir Cell Mol Biol. 2000;22(6):665-671.
23. Ihalin R, Loimaranta V, Tenovuo J: Origin, structure, and biological activities of peroxidases in human saliva. Arch Biochem Biophys. 2006;445(2):261-268.
24. Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB, Jr., Nauseef WM, Dupuy C, B́ anfi B: A novel host defense system of airways is defective in cystic fibrosis. Am J Respir Crit Care Med. 2007;175(2):174-183.
25. Veit G, Bossard F, Goepp J, Verkman AS, Galietta LJ, Hanrahan JW, Lukacs GL: Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell. 2012;23(21): 4188-4202.
26. dos Santos CC, Han B, Andrade CF, Bai X, Uhlig S, Hubmayr R, Tsang M, Lodyga M, Keshavjee S, Slutsky AS, Liu M: DNA microarray analysis of gene expression in alveolar epithelial cells in response to TNFalpha, LPS, and cyclic stretch. Physiol Genom. 2004;19(3):331-342.
27. Chaung HC, Lien Y, Chung WB: Leukotriene C4 release and gene expressions of IL-8 and MCP-1 in porcine alveolar epithelial type II cells. Res Vet Sci. 2009;86(1):78-87.
28. Ma X, Xu D, Ai Y, Ming G, Zhao S: Fas inhibition attenuates lipopolysaccharide-induced apoptosis and cytokine release of rat type II alveolar epithelial cells. Mol Biol Rep. 2010;37(7):3051-3056.
29. Xu SF, Wang P, Liu RJ, Zhao J, Zhang XN, Fu ZZ, Gao LM, Liang ZX, Sun JP, Chen LA: Perfluorocarbon attenuates lipopolysaccharide-mediated inflammatory responses of alveolar epithelial cells in vitro. Chin Med J. 2011;124(16):2534-2539.
30. Bao Z, Ye Q, Gong W, Xiang Y, Wan H: Humanized monoclonal antibody against the chemokine CXCL-8 (IL-8) effectively prevents acute lung injury. Int Immunopharmacol. 2010;10(2):259-263.
31. Kurdowska A, Noble JM, Grant IS, Robertson CR, Haslett C, Donnelly SC: Anti-interleukin-8 autoantibodies in patients at risk for acute respiratory distress syndrome. Crit Care Med. 2002;30(10):2335-2337.
32. Kurdowska A, Noble JM, Steinberg KP, Ruzinski JT, Hudson LD, Martin TR: Anti-interleukin 8 autoantibody: Interleukin 8 complexes in the acute respiratory distress syndrome. Relationship between the complexes and clinical disease a ctivity. Am J Respir Crit Care Med. 2001;163(2):463-468.
33. Lieber M, Smith B, Szakal A, Nelson-Rees W, Todaro G: A continuous tumor-cell line from a human lung carcinoma with propertie s of type II alveolar epithelial cells. Int J Cancer. 1976;17(1):62-70.
34. Geiser T, Atabai K, Jarreau PH, Ware LB, Pugin J, Matthay MA: Pulmonary edema fluid from patients with ac ute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism. Am J Respir Crit Care Med. 2001;163(6):1384-1388.
35. Ohwada A, Yoshioka Y, Iwabuchi K, Nagaoka I, Dambara T, Fukuchi Y: VEGF regulates the proliferation of acid-exposed alveolar lining epithelial cells. Thorax. 2003;58(4):328-332.
36. Ware LB, Fang X, Matthay MA: Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol. 2003;285(3):L514-L521.
37. Pechkovsky DV, Zissel G, Goldmann T, Einhaus M, Taube C, Magnussen H, Schlaak M, Muller-Quernheim J: Pattern of NOS2 and NOS3 mRNA expression in human A549 cells and primary cultured AEC II. Am J Ph ysiol Lung Cell Mol Physiol. 2002;282(4):L684-L692.