Effect of improved fitness beyond weight loss on cardiovascular risk factors in individuals with type 2 diabetes in the Look AHEAD study

European Journal of Preventive Cardiology

Volumn 21, Issue 5, 2014, Pages 608-617

  Gibbs, Bethany Barone ^a,b   Brancati, Frederick L ^a   Chen, Haiying ^c   Coday, MacE ^d   Jakicic, John M ^b   Lewis, Cora E ^e   Stewart, Kerry J ^a   Clark, Jeanne M ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cardiovascular risk factor; fitness; lifestyle intervention; obesity

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; TRIACYLGLYCEROL; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; CARDIOVASCULAR RISK; CONTROLLED STUDY; FEMALE; FITNESS; HUMAN; LIFESTYLE MODIFICATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; WALKING SPEED; WEIGHT CHANGE; WEIGHT REDUCTION; ATTITUDE TO HEALTH; BLOOD; CARDIOVASCULAR DISEASES; CLINICAL TRIAL; COMPARATIVE STUDY; DIABETES MELLITUS, TYPE 2; DIET; EXERCISE; GLUCOSE BLOOD LEVEL; METABOLISM; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PATHOPHYSIOLOGY; PATIENT EDUCATION; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; STATISTICAL MODEL; TIME; TREATMENT OUTCOME; UNITED STATES;

AGED; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; DIABETES MELLITUS, TYPE 2; DIET; EXERCISE; FEMALE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; LINEAR MODELS; LIPIDS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATIENT EDUCATION AS TOPIC; PHYSICAL FITNESS; RISK ASSESSMENT; RISK FACTORS; RISK REDUCTION BEHAVIOR; TIME FACTORS; TREATMENT OUTCOME; UNITED STATES; WEIGHT LOSS;

EID: 84900436076     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487312462823     Document Type: Article

References (27)

1. Vidal J. Updated review on the benefits of weight loss. Int J Obes Relat Metab Disord. 2002 ; 26: S25 - S28
2. Pi-Sunyer X, Blackburn G, Brancati FL, et al. Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial. Diabetes Care. 2007 ; 30 (6). 1374-1383
3. Warburton DE, Nicol CW, Bredin SS. Health benefits of physical activity: the evidence. CMAJ. 2006 ; 174 (6). 801-809
4. Balducci S, Zanuso S, Nicolucci A, et al. Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss. Nutr Metab Cardiovasc Dis. 2010 ; 20 (8). 608-617
5. Ryan DH, Espeland MA, Foster GD, et al. Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Control Clin Trials. 2003 ; 24 (5). 610-628
6. Borg GA. Perceived exertion. Exerc Sport Sci Rev. 1974 ; 2: 131-153
7. Wadden TA, West DS, Delahanty L, et al. The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. Obesity (Silver Spring). 2006 ; 14 (5). 737-752
8. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972 ; 18 (6). 499-502
9. ACSM's guidelines for exercise testing and prescription. 8 th edn. Philadelphia: Lippincott Williams and Wilkins, 2010. Philadelphia: Lippincott Williams and Wilkins ; 2010 :
10. Jakicic JM, Jaramillo SA, Balasubramanyam A, et al. Effect of a lifestyle intervention on change in cardiorespiratory fitness in adults with type 2 diabetes: results from the Look AHEAD Study. Int J Obes (Lond). 2009 ; 33 (3). 305-316
11. Thomas DE, Elliott EJ, Naughton GA. Exercise for type 2 diabetes mellitus. Cochrane Database Syst Rev. 2006 ; (3): CD002968 - CD002968
12. Donnelly JE, Blair SN, Jakicic JM, et al. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults. Med Sci Sports Exerc. 2009 ; 41 (2). 459-471
13. Boule NG, Haddad E, Kenny GP, et al. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA. 2001 ; 286 (10). 1218-1227
14. Boule NG, Kenny GP, Haddad E, et al. Meta-analysis of the effect of structured exercise training on cardiorespiratory fitness in Type 2 diabetes mellitus. Diabetologia. 2003 ; 46 (8). 1071-1081
15. Colberg SR, Grieco CR. Exercise in the treatment and prevention of diabetes. Curr Sports Med Rep. 2009 ; 8 (4). 169-1675
16. Kelley GA, Kelley KS. Effects of aerobic exercise on lipids and lipoproteins in adults with type 2 diabetes: a meta-analysis of randomized-controlled trials. Public Health. 2007 ; 121 (9). 643-655
17. Durstine JL, Grandjean PW, Davis PG, et al. Blood lipid and lipoprotein adaptations to exercise: a quantitative analysis. Sports Med. 2001 ; 31 (15). 1033-1062
18. Durstine JL, Grandjean PW, Cox CA, et al. Lipids, lipoproteins, and exercise. J Cardiopulm Rehabil. 2002 ; 22 (6). 385-398
19. Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc. 2004 ; 36 (3). 533-553
20. Balducci S, Zanuso S, Nicolucci A, et al. Effect of an intensive exercise intervention strategy on modifiable cardiovascular risk factors in subjects with type 2 diabetes mellitus: a randomized controlled trial: the Italian Diabetes and Exercise Study (IDES). Arch Intern Med. 2010 ; 170 (20). 1794-1803
21. Zanuso S, Jimenez A, Pugliese G, et al. Exercise for the management of type 2 diabetes: a review of the evidence. Acta Diabetol. 2010 ; 47 (1). 15-22
22. Estruch R, Martinez-Gonzalez MA, Corella D, et al. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med. 2006 ; 145 (1). 1-11
23. Abete I, Goyenechea E, Zulet MA, et al. Obesity and metabolic syndrome: potential benefit from specific nutritional components. Nutr Metab Cardiovasc Dis. 2011 ; 21: B1 - B15
24. Taylor CB, Conrad A, Wilhelm FH, et al. Does improving mood in depressed patients alter factors that may affect cardiovascular disease risk?. J Psychiatr Res. 2009 ; 43 (16). 1246-1252
25. Blumenthal JA, Sherwood A, Babyak MA, et al. Effects of exercise and stress management training on markers of cardiovascular risk in patients with ischemic heart disease: a randomized controlled trial. JAMA. 2005 ; 293 (13). 1626-1634
26. Ordovas JM, Shen J. Gene-environment interactions and susceptibility to metabolic syndrome and other chronic diseases. J Periodontol. 2008 ; 79 (8 Suppl). 1508-1513
27. Lekakis J, Abraham P, Balbarini A, et al. Methods for evaluating endothelial function: a position statement from the European Society of Cardiology Working Group on Peripheral Circulation. Eur J Cardiovasc Prev Rehabil. 2011 ; 18 (6). 775-789