Emerging filoviral disease in Uganda: Proposed explanations and research directions

American Journal of Tropical Medicine and Hygiene

Volumn 90, Issue 5, 2014, Pages 790-793

  Polonsky, Jonathan A ^a   Wamala, Joseph F ^b   De Clerck, Hilde ^c   Van Herp, Michel ^c   Sprecher, Armand ^c   Porten, Klaudia ^a   Shoemaker, Trevor ^d  

^a European Programme for Intervention Epidemiology Training   (France)

^b MINISTRY OF HEALTH   (Uganda)

^c MÉDECINS SANS FRONTIÈRES   (Belgium)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAT; DISEASE SURVEILLANCE; EBOLA HEMORRHAGIC FEVER; EPIDEMIC; HOST; HUMAN; LABORATORY; MARBURG HEMORRHAGIC FEVER; NONHUMAN; PREVALENCE; REVIEW; SEROPREVALENCE; UGANDA; VIRUS LOAD;

ANIMALS; CHIROPTERA; DISEASE OUTBREAKS; EBOLAVIRUS; HEMORRHAGIC FEVER, EBOLA; HOST-PATHOGEN INTERACTIONS; HUMANS; MARBURG VIRUS DISEASE; MARBURGVIRUS; PREVALENCE; UGANDA; VIRAL LOAD;

EID: 84900408196     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.13-0374     Document Type: Review

References (25)

1. Centers for Disease Control and Prevention, 2005. Outbreak of Marburg virus hemorrhagic fever - Angola, October 1, 2004-March 29, 2005. MMWR Morb Mortal Wkly Rep 54: 308-309.
2. World Health Organization, 2012. Ebola Haemorrhagic Fever. Available at: http://www.who.int/mediacentre/factsheets/fs103/en/. Accessed December 24, 2012.
3. World Health Organization, 2012. Marburg Haemorrhagic Fever. Available at: http://www.who.int/mediacentre/factsheets/fs-marburg/en/. Accessed December 24, 2012.
4. Towner JS, Amman BR, Sealy TK, Carroll SAR, Comer JA, Kemp A, Swanepoel R, Paddock CD, Balinandi S, Khristova ML, Formenty PBH, Albarino CG, Miller DM, Reed ZD, Kayiwa JT, Mills JN, Cannon DL, Greer PW, Byaruhanga E, Farnon EC, Atimnedi P, Okware S, Katongole-Mbidde E, Downing R, Tappero JW, Zaki SR, Ksiazek TG, Nichol ST, Rollin PE, 2009. Isolation of genetically diverse marburg viruses from Egyptian fruit bats. PLoS Pathog 5: e1000536.
5. Leroy EM, Kumulungui B, Pourrut X, Rouquet P, Hassanin A, Yaba P, Délicat A, Paweska JT, Gonzalez J-P, Swanepoel R, 2005. Fruit bats as reservoirs of Ebola virus. Nature 438: 575-576. (Pubitemid 41740557)
6. Leroy EM, Epelboin A, Mondonge V, Pourrut X, Gonzalez J-P, Muyembe-Tamfum J-J, Formenty P, 2009. Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo, 2007. Vector Borne Zoonotic Dis 9: 723-728.
7. Pourrut X, Souris M, Towner JS, Rollin PE, Nichol ST, Gonzalez J-P, Leroy E, 2009. Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus. BMC Infect Dis 9: 159.
8. Okware SI, Omaswa FG, Zaramba S, Opio A, Lutwama JJ, Kamugisha J, Rwaguma EB, Kagwa P, Lamunu M, 2002. An outbreak of Ebola in Uganda. Trop Med Int Health 7: 1068-1075. (Pubitemid 36960256)
9. Borchert M, Mutyaba I, Van Kerkhove MD, Lutwama J, Luwaga H, Bisoborwa G, Turyagaruka J, Pirard P, Ndayimirije N, Roddy P, Van Der Stuyft P, Van Kerkhove MD, 2011. Ebola haemorrhagic fever outbreak in Masindi District, Uganda: outbreak description and lessons learned. BMC Infect Dis 11: 357.
10. Adjemian J, Farnon EC, Tschioko F, Wamala JF, Byaruhanga E, Bwire GS, Kansiime E, Kagirita A, Ahimbisibwe S, Katunguka F, Jeffs B, Lutwama JJ, Downing R, Tappero JW, Formenty P, Amman B, Manning C, Towner J, Nichol ST, Rollin PE, 2011. Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007. J Infect Dis 204 (Suppl 3): S796-S799.
11. Towner JS, Sealy TK, Khristova ML, Albariño CG, Conlan S, Reeder SA, Quan P-L, Lipkin WI, Downing R, Tappero JW, Okware S, Lutwama J, Bakamutumaho B, Kayiwa J, Comer JA, Rollin PE, Ksiazek TG, Nichol ST, 2011. Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog 4: e1000212.
12. Wamala JF, Lukwago L, Malimbo M, Nguku P, Yoti Z, Musenero M, Amone J, Mbabazi W, Nanyunja M, Zaramba S, Opio A, Lutwama JJ, Talisuna AO, Okware SI, 2010. Ebola hemorrhagic fever associated with novel virus strain, Uganda, 2007-2008. Emerg Infect Dis 16: 1087-1092.
13. Centers for Disease Control and Prevention, 2010. Imported case of Marburg hemorrhagic fever - Colorado, 2008. MMWR Morb Mortal Wkly Rep 303: 413-415.
14. Timen A, Koopmans MPG, Vossen ACTM, van Doornum GJJ, Günther S, van den Berkmortel F, Verduin KM, Dittrich S, Emmerich P, Osterhaus ADME, van Dissel JT, Coutinho RA, 2009. Response to imported case of Marburg hemorrhagic fever, the Netherlands. Emerg Infect Dis 15: 1171-1175.
15. Shoemaker T, MacNeil A, Balinandi S, Campbell S, Wamala JF, McMullan LK, Downing R, Lutwama J, Mbidde E, Ströher U, Rollin PE, Nichol ST, 2012. Reemerging Sudan Ebola virus disease in Uganda, 2011. Emerg Infect Dis 18: 1480-1483.
16. Centers for Disease Control and Prevention, 2012. Outbreak Postings. Available at: http://www.cdc.gov/ncidod/dvrd/spb/outbreaks/index.htm#ebola-2012. Accessed December 24, 2012.
17. Leroy E, Baize S, Gonzalez JP, 2011. Ebola and Marburg hemorrhagic fever viruses: update on filoviruses. Med Trop (Mars) 71: 111-121.
18. MacNeil A, Rollin PE, 2012. Ebola and Marburg hemorrhagic fevers: neglected tropical diseases? PLoS Negl Trop Dis 6: e1546.
19. World Health Organization, 2012. Ebola in Uganda - Update. Available at: http://www.who.int/csr/don/2012-11-30-ebola/en/index.html. Accessed March 21, 2013.
20. Hewlett BS, Amola RP, 2003. Cultural contexts of Ebola in northern Uganda. Emerg Infect Dis 9: 1242-1248. (Pubitemid 37210563)
21. Monath TP, 1999. Ecology of Marburg and Ebola viruses: speculations and directions for future research. J Infect Dis 179 (Suppl 1): S127-S138. (Pubitemid 29091394)
22. Mwavu EN, Witkowski ETF, 2008. Land-use and cover changes (1988-2002) around Budongo Forest Reserve, NW Uganda: implications for forest and woodland sustainability. Land Degradation Dev 19: 606-622.
23. Muehlenbein MP, 2005. Parasitological analyses of the male chimpanzees (Pan troglodytes schweinfurthii) at Ngogo, Kibale National Park, Uganda. Am J Primatol 65: 167-179. (Pubitemid 40452058)
24. Amman BR, Carroll SA, Reed ZD, Sealy TK, Balinandi S, Swanepoel R, Kemp A, Erickson BR, Comer JA, Campbell S, Cannon DL, Khristova ML, Atimnedi P, Paddock CD, Crockett RJ, Flietstra TD, Warfield KL, Unfer R, Katongole-Mbidde E, Downing R, Tappero JW, Zaki SR, Rollin PE, Ksiazek TG, Nichol ST, Towner JS, 2012. Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection. PLoS Pathog 8: e1002877.
25. Maganga GD, Bourgarel M, Ella GE, Drexler JF, Gonzalez J-P, Drosten C, Leroy EM, 2011. Is Marburg virus enzootic in Gabon? J Infect Dis 204 (Suppl 3): S800-S803.