SCOPUS 정보 검색 플랫폼

Journal of the American Chemical Society

Volumn 136, Issue 18, 2014, Pages 6608-6616

Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord

(13) Lee, Yeon Sun a Muthu, Dhanasekaran a Hall, Sara M a Ramos Colon, Cyf a Rankin, David b Hu, Jackie b Sandweiss, Alexander J b De Felice, Milena b Xie, Jennifer Yanhua b Vanderah, Todd W b Porreca, Frank b Lai, Josephine b Hruby, Victor J a

a The University of Arizona (United States)

b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOACTIVITY; RATS;

BINDING AFFINITIES; CENTRAL NERVOUS SYSTEMS; DOSE-DEPENDENT MANNER; HYPERALGESIC EFFECTS; PERIPHERAL NEUROPATHY; STRUCTURAL DISSIMILARITIES; STRUCTURAL FEATURE; STRUCTURE-ACTIVITY RELATIONSHIPS;

LIGANDS;

BRADYKININ; BRADYKININ RECEPTOR; DYNORPHIN A; DYNORPHIN A DERIVATIVE; DYNORPHIN A[4-11]; ICATIBANT; KALLIDIN; OPIATE RECEPTOR; UNCLASSIFIED DRUG; [7 DES ARGININE] DYNORPHIN A[4-11]; DYNORPHIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CENTRAL NERVOUS SYSTEM; CHRONIC PAIN; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; HYPERALGESIA; IN VIVO STUDY; LIGAND BINDING; MALE; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MOTOR DYSFUNCTION; NERVE CELL EXCITABILITY; NERVE INJURY; NONHUMAN; PERIPHERAL NEUROPATHY; PHARMACOPHORE; RAT; SPINAL CORD; STRUCTURE ACTIVITY RELATION; UPREGULATION; ANIMAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; SPRAGUE DAWLEY RAT;

ANIMALS; DYNORPHINS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, BRADYKININ; SPINAL CORD; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84900345297 PISSN: 00027863 EISSN: 15205126 Source Type: Journal
DOI: 10.1021/ja501677q Document Type: Article

Times cited : (25)

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