A de novo germline mutation of APC for inheritable colon cancer in a Chinese family using multigene next generation sequencing

Biochemical and Biophysical Research Communications

Volumn 447, Issue 3, 2014, Pages 503-507

  Zhang, Yan ^a   Lu, Guanting ^b   Hu, Qingtao ^c,d   Wang, Xueyan ^b   Li, Chaohua ^b   Mao, Yuegan ^b   Cui, Manhua ^a  

^a THE SECOND HOSPITAL OF JILIN UNIVERSITY   (China)

^b Beijing Yishengxingye Science and Technology Co Ltd   (China)

^c Chinese Academy of Sciences   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

De novo germline mutation; Inheritable colon cancer; Premature stop codon

Indexed keywords

APC PROTEIN; GENOMIC DNA;

ADULT; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CHINESE; CLINICAL ARTICLE; COLON CANCER; FAMILIAL COLON POLYPOSIS; FEMALE; GENE SEQUENCE; GERMLINE MUTATION; HUMAN; MALE; NONSENSE MEDIATED MRNA DECAY; PEDIGREE; PRIORITY JOURNAL; STOP CODON;

DE NOVO GERMLINE MUTATION; INHERITABLE COLON CANCER; PREMATURE STOP CODON;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; PEDIGREE;

EID: 84900330220     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.04.014     Document Type: Article

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