Success stories about severe pneumonia caused by Panton-Valentine leucocidin-producing Staphylococcus aureus

Brazilian Journal of Infectious Diseases

Volumn 18, Issue 3, 2014, Pages 341-345

  Elisabeth, Paramythiotou ^a   Maria, Souli ^a   Irene, Galani ^a   Helen, Giamarellou ^a,b   Apostolos, Armaganidis ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b HYGEIA HOSPITAL   (Greece)

Author keywords

Clindamycin; Community acquired pneumonia; Panton Valentine leukocidin; Staphylococcus aureus

Indexed keywords

ACTIVATED PROTEIN C; CARBAPENEM; CEFTRIAXONE; CLARITHROMYCIN; COLISTIN; HYDROCORTISONE; LINEZOLID; MOXIFLOXACIN; NORADRENALIN; OSELTAMIVIR; PANTON VALENTINE LEUKOCIDIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TIGECYCLINE; CLINDAMYCIN; DAPTOMYCIN;

ADD ON THERAPY; ADULT; ARTICLE; BACTERIAL PNEUMONIA; BLOOD GAS ANALYSIS; BRONCHOSCOPY; CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE; CASE REPORT; COMMUNITY ACQUIRED PNEUMONIA; COMPUTER ASSISTED TOMOGRAPHY; COUGHING; CRACKLE; DISEASE SEVERITY; EMPYEMA; FEMALE; FEVER; FLU LIKE SYNDROME; HUMAN; KLEBSIELLA PNEUMONIAE; LEUKOPENIA; LUNG AUSCULTATION; LUNG INFLATION; MALE; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; NONHUMAN; PLEURA EFFUSION; PNEUMOTHORAX; RESPIRATORY DISTRESS; RESPIRATORY FAILURE; SEPTIC SHOCK; SPUTUM ANALYSIS; STAPHYLOCOCCAL BACTEREMIA; STAPHYLOCOCCUS AUREUS; THORAX PAIN; THORAX RADIOGRAPHY; VENTILATOR ASSOCIATED PNEUMONIA; WEAKNESS; BACTEREMIA; BACTERIAL STRAIN; BACTERIUM ISOLATE; COMMUNITY ACQUIRED NECROTIZING PNEUMONIA; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; IN VITRO STUDY; INTENSIVE CARE UNIT; LUNG ABSCESS; PLEURA EMPYEMA; SPONTANEOUS PNEUMOTHORAX; TRACHEOSTOMY;

CLINDAMYCIN; COMMUNITY-ACQUIRED PNEUMONIA; PANTON-VALENTINE LEUKOCIDIN; STAPHYLOCOCCUS AUREUS;

ADOLESCENT; ADULT; BACTERIAL TOXINS; COMMUNITY-ACQUIRED INFECTIONS; EXOTOXINS; FEMALE; HUMANS; LEUKOCIDINS; MALE; NECROSIS; PNEUMONIA, STAPHYLOCOCCAL; SEVERITY OF ILLNESS INDEX; STAPHYLOCOCCUS AUREUS;

EID: 84900011401     PISSN: 14138670     EISSN: 16784391     Source Type: Journal    
DOI: 10.1016/j.bjid.2013.11.011     Document Type: Article

References (24)

1. Moran G.J., Krishnadasan A., Gorwitz R., et al. Prevalence of methicillin-resistant Staphylococcus aureus as an etiology of community-acquired pneumonia. Clin Infect Dis 2012, 54:1126-1133. for the EMERGENCY ID NET Study Group.
2. Vardakas K., Matthaiou D., Falagas M. Incidence, characteristics and outcome of patients with severe community acquired - MRSA pneumonia. Eur Respir J 2009, 34:1148-1158.
3. Lina G., Piemont Y., Godail-Gamot F., et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999, 29:1128-1132.
4. Dumitrescu O., Boisset S., Badiou C. Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. Antimicrob Agents Chemother 2007, 51:1515-1519.
5. Tsangaris I., Paramythiotou E., Tsaknis G. Ovarian hyperstimulation syndrome complicated by severe community-acquired pneumonia due to methicillin-resistant Staphylococcus aureus positive for Panton-Valentine leukocidin. J Obstet Gynaecol Res 2012, 38:476-478.
6. Lina G., Piémont Y., Godail-Gamot F., et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis 1999, 29:1128-1132.
7. Milheiric C., Oliveira D.C., de Lencastre H. Multiplex PCR strategy for subtyping the staphylococcal cassette chromosome mec type IV in methicillin-resistant Staphylococcus aureus: 'SCCmec IV multiplex'. J Antimicrob Chemother 2007, 60:42-48.
8. Chini V., Petinaki E., Foka A., et al. Spread of Staphylococcus aureus clinical isolates carrying Panton-Valentine leukocidin genes during a 3-year period in Greece. Clin Microbiol Infect 2006, 12:29-34.
9. Drougka E., Foka A., Marangos M.N. The first case of Staphylococcus aureus ST398 causing bacteremia in an immunocompromised patient in Greece. Indian J Med Microbiol 2012, 30:232-236.
10. Balis E., Diakaki C., Tselioti P. Community-acquired pneumonia and bacteremia due to methicillin-resistant Staphylococcus aureus carrying Panton-Valentine-leukocidin gene in Greece: two case reports and literature review. J Chemother 2007, 19:703-708.
11. Magira E., Zervakis D., Routsi C., et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes; a lethal cause of pneumonia in an adult immunocompetent patient. Scand J Infect Dis 2007, 39:466-469.
12. Vardakas K., Matthaiou D., Falagas M. Comparison of community-acquired pneumonia due to methicillin-resistant and methicillin-susceptible Staphylococcus aureus producing the Panton-Valentine leukocidin. Int J Tuberc Lung Dis 2009, 13:1476-1485.
13. Gillet Y., Vanhems P., Lina G., et al. Factors predicting mortality in necrotizing community-acquired pneumonia caused by Staphylococcus aureus containing Panton-Valentine leukocidin. Clin Infect Dis 2007, 45:315-321.
14. Dumitresku O., Badiou C., Bes M., et al. Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureus reference strain. Clin Microbiol Infect 2008, 14:384-388.
15. Stevens D.L., Ma Y., Mcndoo E., Wallace R.J., Bryant A. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus. J Infect Dis 2007, 195:202-211.
16. Morgan M.S. Diagnosis and treatment of Panton-Valentine leukocidin (PVL)-associated Staphylococcal pneumonia. Intern J Antimicrob Agents 2007, 30:289-296.
17. Van Langeveldes P., van Dissel C.J.C., Renz J., Groeneveld P.H.P. Combination of flucloxacillin and gentamicin inhibits toxic shock syndrome toxin 1 production by Staphylococcus aureus in both logarithmic and stationary phases of growth. Antimicrob Agents Chemother 1997, 41:1682-1685.
18. Ohlsen K., Ziebuhr W., Koller P., et al. Effects of subinhibitory concentrations of antibiotics on alpha toxin gene expression of methicillin sensitive and methicillin resistant Staphylococcus aureus isolates. Antimicrob Agents Chemother 1997, 42. 2817 23.
19. Rouzic N., Janvier F., Libert N., et al. Prompt and successful toxin targeting treatment of three patients with necrotizing pneumonia due to Staphylococcus aureus strains carrying the Panton-Valentine leukocidin genes. J Clin Microbiol 2010, 48:1952-1955.
20. Micek S.T., Dunne M., Kollef M.H. Pleuropulmonary complications of Panton-Valentine leukocidin positive community acquired methicillin-resistant Staphylococcus aureus: importance of treatment with antimicrobials inhibiting exotoxin production. Chest 2005, 128:2732-2738.
21. Gauduchon V., Cozon G., Vandenesh F. Neutralization of Staphylococcus aureus Panton-Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis 2004, 189:346-353.
22. Libert N., Batjorrn E., Cirodde A., et al. Antitoxin treatments for necrotizing pneumonia due to Panton-Valentine leukocidin-secreting Staphylococcus aureus. Med Mal Infect 2009, 39:14-20.
23. Salliot C., Zeller V., Puechal X., et al. Panton-Valentine leukocidin-producing Staphylococcus aureus infections: report of 4 French cases. Scand J Infect Dis 2006, 38:192-234.
24. Martinez-Olondris P., Rigol M., Soy D., et al. Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs. Crit Care Med 2012, 40:162-168.