PRP treatment effects on degenerative tendinopathy - An in vitromodel study

Muscles, Ligaments and Tendons Journal

Volumn 4, Issue 1, 2014, Pages 10-17

  Zhang, Jianying ^a   Wang, James H C ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Degenerative tendinopathy; Disease in a dish model; PRP; Tendon stem cells

Indexed keywords

EID: 84900002999     PISSN: None     EISSN: 22404554     Source Type: Journal    
DOI: 10.32098/mltj.01.2014.03     Document Type: Article

References (33)

1. Khan KM, Maffuli N. Tendinopathy: an Achilles' heel for athletes and clinicians. Clin J Sport Med. 1998; 8:151-154.
2. Almekinders LC, Temple JD. Etiology, diagnosis, and treatment of tendonitis: an analysis of the literature. Med Sci Sports Exerc. 1998;30:1183-1190.
3. Kannus P, Jozsa L. Histopathological changes preceding spontaneous rupture of a tendon. A controlled study of 891 patients. J Bone Joint Surg Am. 1991;73:1507-1525.
4. Riley G. The pathogenesis of tendinopathy. A molecular perspective. Rheumatology (Oxford) 2004; 43:131-142.
5. Wang JH, Iosifidis MI, Fu FH. Biomechanical basis for tendinopathy. Clin Orthop Relat Res 2006;443:320-332.
6. Bi Y, Ehirchiou D, Kilts TM, Inkson CA, Embree MC, et al. Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med. 2007; 13:1219-1227.
7. Zhang J, Wang JH. Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskelet Disord. 2010;11:10-20.
8. Rui YF, Lui PP, Li G, Fu SC, Lee YW, et al. Isolation and characterization of multipotent rat tendon-derived stem cells. Tissue Eng Part A. 2010;16:1549-1558.
9. Zhou Z, Akinbiyi T, Xu L, Ramcharan M, Leong DJ, et al. Tendon-derived stem/progenitor cell aging: defective self-renewal and altered fate. Aging Cell. 2010; 9:911-915.
10. Zhang J, Wang JH. Mechanobiological response of tendon stem cells: implications of tendon homeostasis and pathogen-esis of tendinopathy. J Orthop Res. 2010; 28:639-643.
11. Chang J, Thunder R, Most D, Longaker MT, Lineaweaver WC. Studies in flexor tendon wound healing: neutralizing antibody to TGF-beta1 increases postoperative range of motion. Plast Reconstr Surg. 2000;105:148-155.
12. Hsu C, Chang J. Clinical implications of growth factors in flexor tendon wound healing. J Hand Surg Am. 2004;29:551-563.
13. Molloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing. Sports Med. 2003;33:381-394.
14. Wang JH. Mechanobiology of tendon. J Biomech. 2006;39: 1563-1582.
15. Foster TE, Puskas BL, Mandelbaum BR, Gerhardt MB, Rodeo SA. Platelet-rich plasma: from basic science to clinical applications. Am J Sports Med. 2009;37:2259-2272.
16. Murray MM, Spindler KP, Abreu E, Muller JA, Nedder A, et al. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res. 2007;25:81-91.
17. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med. 2006;34: 1774-1778.
18. Sanchez M, Anitua E, Azofra J, Andia I, Padilla S, et al. Comparison of surgically repaired Achilles tendon tears using platelet-rich fibrin matrices. Am J Sports Med. 2007; 35:245-251.
19. de Vos RJ, Weir A, van Schie HT, Bierma-Zeinstra SM, Ver-haar JA, et al. Platelet-rich plasma injection for chronic Achilles tendinopathy: a randomized controlled trial. JAMA. 2010;303: 144-149.
20. Zhang J, Wang JH. The effects of mechanical loading on tendons - an in vivo and in vitro model study. PLoS One. 2013;8: e71740.
21. Vogel G. Stem cells. Diseases in a dish take off. Science 2010;330:1172-1173.
22. Tiscornia G, Vivas EL, Belmonte JC. Diseases in a dish: modeling human genetic disorders using induced pluripotent cells. Nat Med. 2011; 17:1570-1576.
23. Padulo J, Oliva F, Frizziero A, Maffulli N. Muscle, Ligaments and Tendons Journal. Basic principles and recommendations in clinical and field science research. MLTJ. 2013;4:250-252.
24. Zhang J, Wang JH. Platelet-rich plasma releasate promotes differentiation of tendon stem cells into active tenocytes. Am J Sports Med. 2010;38:2477-2486.
25. Anitua E, Andia I, Sanchez M, Azofra J, del Mar Zalduendo M, et al. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res. 2005;23:281-286.
26. Emans PJ, Spaapen F, Surtel DA, Reilly KM, Cremers A, et al. A novel in vivo model to study endochondral bone formation; HIF-1alpha activation and BMP expression. Bone 2007; 40:409-418.
27. Boykiw R, Sciore P, Reno C, Marchuk L, Frank CB, et al. Altered levels of extracellular matrix molecule mRNA in healing rabbit ligaments. Matrix Biol. 1998;17:371-378.
28. Engebretsen L, Steffen K, Alsousou J, Anitua E, Bachl N, et al. IOC consensus paper on the use of platelet-rich plasma in sports medicine. Br J Sports Med. 2010;44:1072-1081.
29. Zhang J, Wang JH. The effects of mechanical loading on tendons - an in vivo and in vitro model study. PLoS One. 2013;8: e71740.
30. Zhang J, Middleton KK, Fu FH, Im HJ, Wang JH. HGF mediates the anti-inflammatory effects of PRP on injured tendons. PLoS One. 2013;8:e67303.
31. Gill TJ, Carroll KM, Hariri S. Open Patellar Tendon Debride-ment for Treatment of Recalcitrant Patellar Tendinopathy: Indications, Technique, and Clinical Outcomes After a 2-Year Minimum Follow-up. Sports Health: 2013;5:276-280.
32. Witt BL, Hyer CF. Achilles tendon reattachment after surgical treatment of insertional tendinosis using the suture bridge technique: a case series. J Foot Ankle Surgery. 2012;51:487-493.
33. Alfredson H, Cook J. A treatment algorithm for managing Achilles tendinopathy: new treatment options. Br J Sports Med. 2007;41:211-216.