Evaluation of a starch-based double layer scaffold for bone regeneration in a rat model

Journal of Orthopaedic Research

Volumn 32, Issue 7, 2014, Pages 904-909

  Requicha, Joao F ^a,b   Moura, Tiago ^a   Leonor, Isabel B ^b   Martins, Teresa ^a,b   Muñoz, Fernando ^c   Reis, Rui L ^b   Gomes, Manuela E ^b   Viegas, Carlos A ^a,b  

^a UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^b UNIVERSITY OF MINHO   (Portugal)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

bone regeneration; mandibular model; rat; scaffold; silanol groups

Indexed keywords

COLLAGEN; POLYCAPROLACTONE; STARCH; TISSUE SCAFFOLD;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REGENERATION; CONTROLLED STUDY; MALE; MANDIBLE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; RAT; TISSUE REGENERATION;

BONE REGENERATION; MANDIBULAR MODEL; RAT; SCAFFOLD; SILANOL GROUPS;

ANIMALS; BONE REGENERATION; CELL DIFFERENTIATION; COLLAGEN; GUIDED TISSUE REGENERATION; INFLAMMATION; MALE; MANDIBLE; OSTEOGENESIS; POLYESTERS; RATS; RATS, WISTAR; SILANES; STARCH; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS; X-RAY MICROTOMOGRAPHY;

EID: 84899996303     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.22609     Document Type: Article

References (34)

1. Petrovic V, Zivkovic P, Petrovic D, et al. 2012. Craniofacial bone tissue engineering. Oral Surg Oral Med Oral Pathol Oral Radiol 114: e1-e9.
2. Lin NH, Gronthos S, Bartold PM,. 2008. Stem cells and periodontal regeneration. Aust Dent J 53: 108-121.
3. Mrozik KM, Gronthos S, Menicanin D, et al. 2012. Effect of coating Straumann Bone Ceramic with Emdogain on mesenchymal stromal cell hard tissue formation. Clin Oral Investig 16: 867-878.
4. Tobita M, Uysal AC, Ogawa R, et al. 2008. Periodontal tissue regeneration with adipose-derived stem cells. Tissue Eng Part A 14: 945-953.
5. Chen FM, An Y, Zhang R, et al. 2011. New insights into and novel applications of release technology for periodontal reconstructive therapies. J Control Release 149: 92-110.
6. Nevins M, Giannobile WV, McGuire MK, et al. 2005. Platelet-derived growth factor stimulates bone fill and rate of attachment level gain: results of a large multicenter randomized controlled trial. J Periodontol 76: 2205-2215.
7. Govender S, Csimma C, Genant HK, et al. 2002. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 84-A: 2123-2134.
8. Dahlin C, Linde A, Gottlow J, et al. 1988. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg 81: 672-676.
9. Sandberg E, Dahlin C, Linde A,. 1993. Bone regeneration by the osteopromotion technique using bioabsorbable membranes: an experimental study in rats. J Oral Maxillofac Surg 51: 1106-1114.
10. Zellin G, Gritli-Linde A, Linde A,. 1995. Healing of mandibular defects with different biodegradable and non-biodegradable membranes: an experimental study in rats. Biomaterials 16: 601-609.
11. Deppe H, Stemberger A,. 2004. Effects of laser-modified versus osteopromotively coated titanium membranes on bone healing: a pilot study in rat mandibular defects. Lasers Med Sci 18: 190-195.
12. Schliephake H, Zghoul N, Jäger V, et al. 2009. Bone formation in trabecular bone cell seeded scaffolds used for reconstruction of the rat mandible. Int J Oral Maxillofac Surg 38: 166-172.
13. Liao S, Wang W, Uo M, et al. 2005. A three-layered nano-carbonated hydroxyapatite/collagen/PLGA composite membrane for guided tissue regeneration. Biomaterials 26: 7564-7571.
14. Kikuchi M, Koyama Y, Yamada T, et al. 2004. Development of guided bone regeneration membrane composed of beta-tricalcium phosphate and poly (l -lactide-co-glycolide-epsilon-caprolactone) composites. Biomaterials 25: 5979-5986.
15. Azevedo HS, Gama FM, Reis RL,. 2003. In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules 4: 1703-1712.
16. Balmayor ER, Tuzlakoglu K, Azevedo HS, et al. 2009. Preparation and characterization of starch-poly-epsilon-caprolactone microparticles incorporating bioactive agents for drug delivery and tissue engineering applications. Acta Biomater 5: 1035-1045.
17. Carvalho PP, Leonor IB, Smith BJ, et al. 2013. Undifferentiated human adipose-derived stromal/stem cells loaded onto wet-spun starch-polycaprolactone scaffolds enhance bone regeneration: Nude mice calvarial defect in vivo study. J Biomed Mater Res Part A DOI: 10.1002/jbm.a.34983
18. Gomes ME, Godinho JS, Tchalamov D, et al. 2002. Alternative tissue engineering scaffolds based on starch: processing methodologies, morphology, degradation and mechanical properties. Mater Sci Eng C 20: 19-26.
19. Gomes ME, Azevedo HS, Moreira AR, et al. 2008. Starch-poly (epsilon-caprolactone) and starch-poly (lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour. J Tissue Eng Regen Med 2: 243-252.
20. Leonor IB, Rodrigues MT, Gomes ME, et al. 2011. In situ functionalization of wet-spun fibre meshes for bone tissue engineering. J Tissue Eng Regen Med 5: 104-111.
21. Rodrigues AI, Gomes ME, Leonor IB, et al. 2012. Bioactive starch based scaffolds and human adipose stem cells are a good combination for bone tissue engineering. Acta Biomater 8: 3765-3776.
22. Link DP, Gardel LS, Correlo VM, et al. 2013. Osteogenic properties of starch poly (ε-caprolactone) (SPCL) fiber meshes loaded with osteoblast-like cells in a rat critical-sized cranial defect. J Biomed Mater Res Part A 101: 3059-3065.
23. Rodrigues MT, Gomes ME, Viegas CA, et al. 2011. Tissue-engineered constructs based on SPCL scaffolds cultured with goat marrow cells: functionality in femoral defects. J Tissue Eng Regen Med 5: 41-49.
24. Reffitt DM, Ogston N, Jugdaohsingh R, et al. 2003. Orthosilicic acid stimulates collagen type 1 synthesis and osteoblastic differentiation in human osteoblast-like cells in vitro. Bone 32: 127-135.
25. Xynos ID, Edgar AJ, Buttery LDK, et al. 2001. Gene-expression profiling of human osteoblasts following treatment with the ionic products of Bioglass® 45S5 dissolution. J Biomed Mater Res 55: 151-157.
26. Requicha JF, Viegas CA, Hede S, et al. 2013. Design and characterization of a biodegradable double-layer scaffold aimed at periodontal tissue-engineering applications. J Tissue Eng Regen Med. DOI: 10.1002/term.1816
27. Donath K, Breuner G,. 1982. A method for the study of undecalcified bones and teeth with attached soft tissues. J Oral Pathol 11: 318-326.
28. Laczkõ J, Lévai G,. 1975. A simple differential staining method for semi-thin sectionsof ossifying cartilage and bone tissues emhedded in epoxy resin. Mikroskopie 31: 1-4.
29. Santos TC, Marques AP, Höring B, et al. 2010. In vivo short-term and long-term host reaction to starch-based scaffolds. Acta Biomater 6: 4314-4326.
30. Stamatialis DF, Papenburg BJ, Girones M, et al. 2008. Medical applications of membranes: drug delivery, artificial organs and tissue engineering. J Membr Sci 308: 1-34.
31. Hoogeveen EJ, Gielkens PFM, Schortinghuis J, et al. 2009. Vivosorb® as a barrier membrane in rat mandibular defects. An evaluation with transversal microradiography. Int J Oral Maxillofac Surg 38: 870-875.
32. van Leeuwen AC, Huddleston Slater JJR, Gielkens PFM, et al. 2012. Guided bone regeneration in rat mandibular defects using resorbable poly (trimethylene carbonate) barrier membranes. Acta Biomater 8: 1422-1429.
33. Parrilla C, Lattanzi W, Rita Fetoni A, et al. 2010. Ex vivo gene therapy using autologous dermal fibroblasts expressing hLMP3 for rat mandibular bone regeneration. Head Neck 32: 310-318.
34. Jiang X, Zhao J, Wang S, et al. 2009. Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials 30: 4522-4532.