Nosocomial transmission of respiratory syncytial virus in an outpatient cancer center

Biology of Blood and Marrow Transplantation

Volumn 20, Issue 6, 2014, Pages 844-851

  Chu, Helen Y ^a   Englund, Janet A ^b,c   Podczervinski, Sara ^d   Kuypers, Jane ^c   Campbell, Angela P ^b,c,e   Boeckh, Michael ^a,b   Pergam, Steven A ^a,b,d   Casper, Corey ^a,b,d  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Infection Control Program   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Health care worker; Infection control; Molecular epidemiology; Outpatient clinic; Respiratory syncytial virus

Indexed keywords

IMMUNOGLOBULIN; PALIVIZUMAB; RIBAVIRIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER CENTER; CANCER PATIENT; CHILD; COHORT ANALYSIS; EPIDEMIC; FEMALE; HEALTH CARE PERSONNEL; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; MAJOR CLINICAL STUDY; MALE; MOLECULAR EPIDEMIOLOGY; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTPATIENT DEPARTMENT; POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SEQUENCE ANALYSIS; VIRUS DETECTION; VIRUS STRAIN; VIRUS TRANSMISSION; CROSS INFECTION; DISEASE TRANSMISSION; GENETICS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; ISOLATION AND PURIFICATION; MIDDLE AGED; NEOPLASMS; OUTPATIENT; PRESCHOOL CHILD; PREVENTION AND CONTROL; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; STATISTICS AND NUMERICAL DATA; TRANSMISSION; VIROLOGY; WASHINGTON; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; CANCER CARE FACILITIES; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; DISEASE OUTBREAKS; FEMALE; HUMANS; INFECTION CONTROL; INFECTIOUS DISEASE TRANSMISSION, PATIENT-TO-PROFESSIONAL; INFECTIOUS DISEASE TRANSMISSION, PROFESSIONAL-TO-PATIENT; MALE; MIDDLE AGED; MOLECULAR EPIDEMIOLOGY; NEOPLASMS; OUTPATIENTS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; WASHINGTON; YOUNG ADULT;

EID: 84899993438     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2014.02.024     Document Type: Article

References (35)

1. Englund J.A., Sullivan C.J., Jordan M.C., et al. Respiratory syncytial virus infection in immunocompromised adults. Ann Intern Med 1988, 109:203-208.
2. Shah D.P., Ghantoji S.S., Shah J.N., et al. Impact of aerosolized ribavirin on mortality in 280 allogeneic haematopoietic stem cell transplant recipients with respiratory syncytial virus infections. J Antimicrob Chemother 2013, 68:1872-1880.
3. Waghmare A., Campbell A.P., Xie H., et al. Respiratory syncytial virus lower respiratory disease in hematopoietic cell transplant recipients: viral RNA detection in blood, antiviral treatment, and clinical outcomes. Clin Infect Dis 2013, 57:1731-1741.
4. Renaud C., Campbell A.P. Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients. Curr Opin Infect Dis 2011, 24:333-343.
5. Boeckh M., Englund J., Li Y., et al. Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients. Clin Infect Dis 2007, 44:245-249.
6. Seo S., Campbell A.P., Xie H., et al. Outcome of respiratory syncytial virus lower respiratory tract disease in hematopoietic cell transplant recipients receiving aerosolized ribavirin: significance of stem cell source and oxygen requirement. Biol Blood Marrow Transplant 2013, 19:589-596.
7. Shah J.N., Chemaly R.F. Management of RSV infections in adult recipients of hematopoietic stem cell transplantation. Blood 2011, 117:2755-2763.
8. Leader S., Kohlhase K. Recent trends in severe respiratory syncytial virus (RSV) among US infants, 1997 to 2000. J Pediatr 2003, 143:S127-S132.
9. Englund J.A., Anderson L.J., Rhame F.S. Nosocomial transmission of respiratory syncytial virus in immunocompromised adults. J Clin Microbiol 1991, 29:115-119.
10. Machado A.F., Sallum M.A., Vilas Boas L.S., et al. Molecular characterization of strains of respiratory syncytial virus identified in a hematopoietic stem cell transplant outpatient unit over 2 years: community or nosocomial infection?. Biol Blood Marrow Transplant 2008, 14:1348-1355.
11. Mazzulli T., Peret T.C., McGeer A., et al. Molecular characterization of a nosocomial outbreak of human respiratory syncytial virus on an adult leukemia/lymphoma ward. J Infect Dis 1999, 180:1686-1689.
12. Peret T.C., Hall C.B., Schnabel K.C., et al. Circulation patterns of genetically distinct group A and B strains of human respiratory syncytial virus in a community. J Gen Virol 1998, 79(Pt 9):2221-2229.
13. Geis S., Prifert C., Weissbrich B., et al. Molecular characterization of a respiratory syncytial virus (RSV) outbreak in a hematology unit, Heidelberg, Germany. J Clin Microbiol 2012, 51:155-162.
14. Sydnor E.R., Greer A., Budd A.P., et al. An outbreak of human parainfluenza virus 3 infection in an outpatient hematopoietic stem cell transplantation clinic. Am J Infect Control 2012, 40:601-605.
15. Garcia R., Raad I., Abi-Said D., et al. Nosocomial respiratory syncytial virus infections: prevention and control in bone marrow transplant patients. Infect Control Hosp Epidemiol 1997, 18:412-416.
16. Kassis C., Champlin R.E., Hachem R.Y., et al. Detection and control of a nosocomial respiratory syncytial virus outbreak in a stem cell transplantation unit: the role of palivizumab. Biol Blood Marrow Transplant 2010, 16:1265-1271.
17. Lavergne V., Ghannoum M., Weiss K., et al. Successful prevention of respiratory syncytial virus nosocomial transmission following an enhanced seasonal infection control program. Bone Marrow Transplant 2011, 46:137-142.
18. McDiarmid S., Hutton B., Atkins H., et al. Performing allogeneic and autologous hematopoietic SCT in the outpatient setting: effects on infectious complications and early transplant outcomes. Bone Marrow Transplant 2010, 45:1220-1226.
19. Kuypers J., Campbell A.P., Cent A., et al. Comparison of conventional and molecular detection of respiratory viruses in hematopoietic cell transplant recipients. Transplant Infect Dis 2009, 11:298-303.
20. Kuypers J., Wright N., Morrow R. Evaluation of quantitative and type-specific real-time RT-PCR assays for detection of respiratory syncytial virus in respiratory specimens from children. J Clin Virol 2004, 31:123-129.
21. Kuypers J., Wright N., Ferrenberg J., et al. Comparison of real-time PCR assays with fluorescent-antibody assays for diagnosis of respiratory virus infections in children. J Clin Microbiol 2006, 44:2382-2388.
22. Chu H.Y., Kuypers J., Renaud C., et al. Molecular epidemiology of respiratory syncytial virus transmission in childcare. J Clin Virol 2013, 57:343-350.
23. Larkin M.A., Blackshields G., Brown N.P., Chenna R., McGettigan P.A., McWilliam H., Valentin F., Wallace I.M., Wilm A., Lopez R., Thompson J.D., Gibson T.J., Higgins D.G. Clustal W and Clustal X version 2.0. Bioinformatics 2007, 23:2947-2948.
24. Tamura K., Peterson D., Peterson N., et al. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011, 28:2731-2739.
25. Seropian S., Nadkarni R., Jillella A.P., et al. Neutropenic infections in 100 patients with non-Hodgkin's lymphoma or Hodgkin's disease treated with high-dose BEAM chemotherapy and peripheral blood progenitor cell transplant: out-patient treatment is a viable option. Bone Marrow Transplant 1999, 23:599-605.
26. Russell J.A., Chaudhry A., Booth K., et al. Early outcomes after allogeneic stem cell transplantation for leukemia and myelodysplasia without protective isolation: a 10-year experience. Biol Blood Marrow Transplant 2000, 6:109-114.
27. Nichols W.G., Erdman D.D., Han A., et al. Prolonged outbreak of human parainfluenza virus 3 infection in a stem cell transplant outpatient department: insights from molecular epidemiologic analysis. Biol Blood Marrow Transplant 2004, 10:58-64.
28. Karanfil L.V., Conlon M., Lykens K., et al. Reducing the rate of nosocomially transmitted respiratory syncytial virus. Am J Infect Control 1999, 27:91-96.
29. Snydman D.R., Greer C., Meissner H.C., McIntosh K. Prevention of nosocomial transmission of respiratory syncytial virus in a newborn nursery. Infect Control Hosp Epidemiol 1988, 9:105-108.
30. Hall C.B., Douglas R.G., Schnabel K.C., Geiman J.M. Infectivity of respiratory syncytial virus by various routes of inoculation. Infect Immun 1981, 33:779-783.
31. Piralla A., Percivalle E., Di Cesare-Merlone A., et al. Multicluster nosocomial outbreak of parainfluenza virus type 3 infection in a pediatric oncohematology unit: a phylogenetic study. Haematologica 2009, 94:833-839.
32. Degail M.A., Hughes G.J., Maule C., et al. A human metapneumovirus outbreak at a community hospital in England, July to September 2010. Bull Eur Mal Transm 2012, 17:1-8.
33. Oguma T., Saito R., Masaki H., et al. Molecular characteristics of outbreaks of nosocomial infection with influenza A/H3N2 virus variants. Infect Control Hosp Epidemiol 2011, 32:267-275.
34. Pretorius M.A., van Niekerk S., Tempia S., et al. Replacement and positive evolution of subtype A and B respiratory syncytial virus G-protein genotypes from 1997-2012 in South Africa. J Infect Dis 2013, 208(Suppl. 3):S227-S237.
35. Yoshida A., Kiyota N., Kobayashi M., et al. Molecular epidemiology of the attachment glycoprotein (G) gene in respiratory syncytial virus in children with acute respiratory infection in Japan in 2009/2010. J Med Microbiol 2012, 61:820-829.