1,2-Dibromo-4-(1,2-dibromoethyl)-cyclohexane and tris(methylphenyl) phosphate cause significant effects on development, mRNA expression, and circulating bile acid concentrations in chicken embryos

Toxicology and Applied Pharmacology

Volumn 277, Issue 3, 2014, Pages 279-287

  Crump, Doug ^a   Porter, Emily ^a   Egloff, Caroline ^a   Williams, Kim L ^a   Letcher, Robert J ^a   Gauthier, Lewis T ^a   Kennedy, Sean W ^a,b  

^a ENVIRONMENT CANADA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

1,2 Dibromo 4 (1,2 dibromoethyl) cyclohexane; Bile acids; Chicken; Embryonic development; MRNA expression; Tris(methylphenyl) phosphate

Indexed keywords

1,2 DIBROMO 4 (1,2 DIBROMOETHYL)CYCLOHEXANE; BILE ACID; CYCLOHEXANE DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 2H1; CYTOCHROME P450 3A37; MESSENGER RNA; THYROID HORMONE; THYROXINE; TRICRESYL PHOSPHATE; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ARTICLE; CHICKEN; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; EMBRYO DEVELOPMENT; EMBRYO GROWTH; LIPID METABOLISM; NONHUMAN; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; XENOBIOTIC METABOLISM;

AVES; SPONDIAS PURPUREA;

1,2-DIBROMO-4-(1,2-DIBROMOETHYL)-CYCLOHEXANE; BILE ACIDS; CHICKEN; EMBRYONIC DEVELOPMENT; MRNA EXPRESSION; TRIS(METHYLPHENYL) PHOSPHATE;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BILE ACIDS AND SALTS; CHICK EMBRYO; CYCLOHEXANES; ENVIRONMENTAL POLLUTANTS; FLAME RETARDANTS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIVER; MOLECULAR STRUCTURE; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; THYROXINE;

EID: 84899972790     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.03.028     Document Type: Article

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