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Volumn 14, Issue 1, 2014, Pages

Phospho-kinase profile of triple negative breast cancer and androgen receptor signaling

Author keywords

AR (Androgen Receptor); EGFR PDFGR ; Erk1 2; Kinase Inhibitors; PI3K mTor; TNBC (triple negative breast cancer); Tyrosine Kinase Receptor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ANDROGEN RECEPTOR; ANDROSTANOLONE; BICALUTAMIDE; DACTOLISIB; EPIDERMAL GROWTH FACTOR RECEPTOR; IMATINIB; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TYROSINE KINASE RECEPTOR; ANILIDE; AR PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; NITRILE; TARGET OF RAPAMYCIN KINASE; TOLUENESULFONIC ACID DERIVATIVE;

EID: 84899941391     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-302     Document Type: Article
Times cited : (48)

References (30)
  • 4
    • 0037204192 scopus 로고    scopus 로고
    • Production and actions of estrogens
    • 10.1056/NEJMra000471, 11821512
    • Gruber CJ, Tschugguel W, Schneeberger C, Huber JC. Production and actions of estrogens. N Engl J Med 2002, 346:340-352. 10.1056/NEJMra000471, 11821512.
    • (2002) N Engl J Med , vol.346 , pp. 340-352
    • Gruber, C.J.1    Tschugguel, W.2    Schneeberger, C.3    Huber, J.C.4
  • 5
    • 0038210242 scopus 로고    scopus 로고
    • Aromatase inhibitors in breast cancer
    • 10.1056/NEJMra023246, 12802030
    • Smith IE, Dowsett M. Aromatase inhibitors in breast cancer. N Engl J Med 2003, 348:2431-2442. 10.1056/NEJMra023246, 12802030.
    • (2003) N Engl J Med , vol.348 , pp. 2431-2442
    • Smith, I.E.1    Dowsett, M.2
  • 6
    • 0242300581 scopus 로고    scopus 로고
    • Androgen receptor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations
    • 10.1309/42F00D0DJD0J5EDT, 14608899
    • Agoff SN, Swanson PE, Linden H, Hawes SE, Lawton TJ. Androgen receptor expression in estrogen receptor-negative breast cancer. Immunohistochemical, clinical, and prognostic associations. Am J Clin Pathol 2003, 120:725-731. 10.1309/42F00D0DJD0J5EDT, 14608899.
    • (2003) Am J Clin Pathol , vol.120 , pp. 725-731
    • Agoff, S.N.1    Swanson, P.E.2    Linden, H.3    Hawes, S.E.4    Lawton, T.J.5
  • 8
    • 79961029891 scopus 로고    scopus 로고
    • Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1
    • 10.1038/emboj.2011.216, 3160190, 21701558
    • Robinson JL, Macarthur S, Ross-Innes CS, Tilley WD, Neal DE, Mills IG, Carroll JS. Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. EMBO J 2011, 30:3019-3027. 10.1038/emboj.2011.216, 3160190, 21701558.
    • (2011) EMBO J , vol.30 , pp. 3019-3027
    • Robinson, J.L.1    Macarthur, S.2    Ross-Innes, C.S.3    Tilley, W.D.4    Neal, D.E.5    Mills, I.G.6    Carroll, J.S.7
  • 9
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • 10.1172/JCI45014, 3127435, 21633166
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y, Pietenpol JA. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011, 121:2750-2767. 10.1172/JCI45014, 3127435, 21633166.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6    Pietenpol, J.A.7
  • 10
    • 84864447342 scopus 로고    scopus 로고
    • Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?
    • 10.1210/me.2012-1107, 3404296, 22745190
    • Hickey TE, Robinson JL, Carroll JS, Tilley WD. Minireview: the androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?. Mol Endocrinol 2012, 26:1252-1267. 10.1210/me.2012-1107, 3404296, 22745190.
    • (2012) Mol Endocrinol , vol.26 , pp. 1252-1267
    • Hickey, T.E.1    Robinson, J.L.2    Carroll, J.S.3    Tilley, W.D.4
  • 11
    • 83655167086 scopus 로고    scopus 로고
    • Androgens and breast cancer
    • 10.1016/j.steroids.2011.10.002, 22015396
    • Kotsopoulos J, Narod SA. Androgens and breast cancer. Steroids 2012, 77:1-9. 10.1016/j.steroids.2011.10.002, 22015396.
    • (2012) Steroids , vol.77 , pp. 1-9
    • Kotsopoulos, J.1    Narod, S.A.2
  • 12
    • 7944234374 scopus 로고    scopus 로고
    • HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
    • 10.1016/j.ccr.2004.09.031, 15542435
    • Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell 2004, 6:517-527. 10.1016/j.ccr.2004.09.031, 15542435.
    • (2004) Cancer Cell , vol.6 , pp. 517-527
    • Mellinghoff, I.K.1    Vivanco, I.2    Kwon, A.3    Tran, C.4    Wongvipat, J.5    Sawyers, C.L.6
  • 13
    • 79960050587 scopus 로고    scopus 로고
    • Targeting androgen receptor in estrogen receptor-negative breast cancer
    • 10.1016/j.ccr.2011.05.026, 3180861, 21741601
    • Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Shirley Liu X, Brown M. Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell 2011, 20:119-131. 10.1016/j.ccr.2011.05.026, 3180861, 21741601.
    • (2011) Cancer Cell , vol.20 , pp. 119-131
    • Ni, M.1    Chen, Y.2    Lim, E.3    Wimberly, H.4    Bailey, S.T.5    Imai, Y.6    Rimm, D.L.7    Shirley Liu, X.8    Brown, M.9
  • 15
    • 34248363956 scopus 로고    scopus 로고
    • Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer
    • 10.1073/pnas.0609139104, 1838515, 17372210
    • Mehrian-Shai R, Chen CD, Shi T, Horvath S, Nelson SF, Reichardt JK, Sawyers CL. Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer. Proc Natl Acad Sci U S A 2007, 104:5563-5568. 10.1073/pnas.0609139104, 1838515, 17372210.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5563-5568
    • Mehrian-Shai, R.1    Chen, C.D.2    Shi, T.3    Horvath, S.4    Nelson, S.F.5    Reichardt, J.K.6    Sawyers, C.L.7
  • 20
    • 79952281692 scopus 로고    scopus 로고
    • P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer
    • 10.1038/onc.2010.489, 21042280
    • Montero JC, Seoane S, Ocana A, Pandiella A. P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer. Oncogene 2011, 30:1059-1071. 10.1038/onc.2010.489, 21042280.
    • (2011) Oncogene , vol.30 , pp. 1059-1071
    • Montero, J.C.1    Seoane, S.2    Ocana, A.3    Pandiella, A.4
  • 21
    • 0033002246 scopus 로고    scopus 로고
    • Cleavage of the TrkA neurotrophin receptor by multiple metalloproteases generates signalling-competent truncated forms
    • 10.1046/j.1460-9568.1999.00552.x, 10103137
    • Diaz-Rodriguez E, Cabrera N, Esparis-Ogando A, Montero JC, Pandiella A. Cleavage of the TrkA neurotrophin receptor by multiple metalloproteases generates signalling-competent truncated forms. Eur J Neurosci 1999, 11:1421-1430. 10.1046/j.1460-9568.1999.00552.x, 10103137.
    • (1999) Eur J Neurosci , vol.11 , pp. 1421-1430
    • Diaz-Rodriguez, E.1    Cabrera, N.2    Esparis-Ogando, A.3    Montero, J.C.4    Pandiella, A.5
  • 22
    • 23044436390 scopus 로고    scopus 로고
    • Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin
    • 10.1158/0008-5472.CAN-04-4023, 16061662
    • Yuste L, Montero JC, Esparis-Ogando A, Pandiella A. Activation of ErbB2 by overexpression or by transmembrane neuregulin results in differential signaling and sensitivity to herceptin. Cancer Res 2005, 65:6801-6810. 10.1158/0008-5472.CAN-04-4023, 16061662.
    • (2005) Cancer Res , vol.65 , pp. 6801-6810
    • Yuste, L.1    Montero, J.C.2    Esparis-Ogando, A.3    Pandiella, A.4
  • 23
    • 16344363218 scopus 로고    scopus 로고
    • Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth
    • 10.1158/1078-0432.CCR-04-1158, 15755991
    • Gregory CW, Whang YE, McCall W, Fei X, Liu Y, Ponguta LA, French FS, Wilson EM, Earp HS. Heregulin-induced activation of HER2 and HER3 increases androgen receptor transactivation and CWR-R1 human recurrent prostate cancer cell growth. Clin Cancer Res 2005, 11:1704-1712. 10.1158/1078-0432.CCR-04-1158, 15755991.
    • (2005) Clin Cancer Res , vol.11 , pp. 1704-1712
    • Gregory, C.W.1    Whang, Y.E.2    McCall, W.3    Fei, X.4    Liu, Y.5    Ponguta, L.A.6    French, F.S.7    Wilson, E.M.8    Earp, H.S.9
  • 24
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
    • Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G, Klocker H. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res 1994, 54:5474-5478.
    • (1994) Cancer Res , vol.54 , pp. 5474-5478
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3    Radmayr, C.4    Trapman, J.5    Hittmair, A.6    Bartsch, G.7    Klocker, H.8
  • 26
    • 77649188673 scopus 로고    scopus 로고
    • Expression of androgen receptors in primary breast cancer
    • 10.1093/annonc/mdp510, 19887463
    • Park S, Koo J, Park HS, Kim JH, Choi SY, Lee JH, Park BW, Lee KS. Expression of androgen receptors in primary breast cancer. Ann Oncol 2010, 21:488-492. 10.1093/annonc/mdp510, 19887463.
    • (2010) Ann Oncol , vol.21 , pp. 488-492
    • Park, S.1    Koo, J.2    Park, H.S.3    Kim, J.H.4    Choi, S.Y.5    Lee, J.H.6    Park, B.W.7    Lee, K.S.8
  • 27
    • 84891935165 scopus 로고    scopus 로고
    • Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer
    • 10.1038/onc.2012.572, 23246963
    • Montero JC, Esparis-Ogando A, Re-Louhau MF, Seoane S, Abad M, Calero R, Ocana A, Pandiella A. Active kinase profiling, genetic and pharmacological data define mTOR as an important common target in triple-negative breast cancer. Oncogene 2014, 33:148-156. 10.1038/onc.2012.572, 23246963.
    • (2014) Oncogene , vol.33 , pp. 148-156
    • Montero, J.C.1    Esparis-Ogando, A.2    Re-Louhau, M.F.3    Seoane, S.4    Abad, M.5    Calero, R.6    Ocana, A.7    Pandiella, A.8
  • 29
    • 84860389637 scopus 로고    scopus 로고
    • Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer
    • 10.1186/bcr2858, 3219199, 21457548
    • Naderi A, Chia K, Liu J. Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer. Breast Cancer Res 2011, 13:R36. 10.1186/bcr2858, 3219199, 21457548.
    • (2011) Breast Cancer Res , vol.13
    • Naderi, A.1    Chia, K.2    Liu, J.3
  • 30
    • 84899965492 scopus 로고    scopus 로고
    • Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer
    • Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer. [http://www.clinicaltrial.gov/ct2/show/NCT00755885?term=abiraterone+and+breast&rank=2].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.