-
1
-
-
73849145729
-
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
-
Davis RE, Ngo VN, Lenz G, Tolar P, Young RM, Romesser PB. et al. Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma. Nature 2010; 463: 88-92.
-
(2010)
Nature
, vol.463
, pp. 88-92
-
-
Davis, R.E.1
Ngo, V.N.2
Lenz, G.3
Tolar, P.4
Young, R.M.5
Romesser, P.B.6
-
2
-
-
84866152172
-
Chronic lymphocytic leukaemia is driven by antigen-independent cellautonomous signalling
-
Duhren-von Minden M, Ubelhart R, Schneider D, Wossning T, Bach MP, Buchner M. et al. Chronic lymphocytic leukaemia is driven by antigen-independent cellautonomous signalling. Nature 2012; 489: 309-312.
-
(2012)
Nature
, vol.489
, pp. 309-312
-
-
Duhren-von Minden, M.1
Ubelhart, R.2
Schneider, D.3
Wossning, T.4
Bach, M.P.5
Buchner, M.6
-
3
-
-
64849113027
-
Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells
-
Gobessi S, Laurenti L, Longo PG, Carsetti L, Berno V, Sica S. et al. Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells. Leukemia 2009; 23: 686-697.
-
(2009)
Leukemia
, vol.23
, pp. 686-697
-
-
Gobessi, S.1
Laurenti, L.2
Longo, P.G.3
Carsetti, L.4
Berno, V.5
Sica, S.6
-
4
-
-
77952886100
-
Spleen tyrosine kinase inhibition prevents chemokine-And integrin-mediated stromal protective effects in chronic lymphocytic leukemia
-
Buchner M, Baer C, Prinz G, Dierks C, Burger M, Zenz T. et al. Spleen tyrosine kinase inhibition prevents chemokine-And integrin-mediated stromal protective effects in chronic lymphocytic leukemia. Blood 2010; 115: 4497-4506.
-
(2010)
Blood
, vol.115
, pp. 4497-4506
-
-
Buchner, M.1
Baer, C.2
Prinz, G.3
Dierks, C.4
Burger, M.5
Zenz, T.6
-
5
-
-
84881475893
-
Fostamatinib inhibits B-cell receptor signaling, cellular activation and tumor proliferation in patients with relapsed and refractory chronic lymphocytic leukemia
-
Herman SE, Barr PM, McAuley EM, Liu D, Wiestner A, Friedberg JW. Fostamatinib inhibits B-cell receptor signaling, cellular activation and tumor proliferation in patients with relapsed and refractory chronic lymphocytic leukemia. Leukemia 2013; 27: 1769-1773.
-
(2013)
Leukemia
, vol.27
, pp. 1769-1773
-
-
Herman, S.E.1
Barr, P.M.2
McAuley, E.M.3
Liu, D.4
Wiestner, A.5
Friedberg, J.W.6
-
6
-
-
84879748062
-
Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia
-
Byrd JC, Furman RR, Coutre SE, Flinn IW, Burger JA, Blum KA. et al. Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia. N Engl J Med 2013; 369: 32-42.
-
(2013)
N Engl J Med
, vol.369
, pp. 32-42
-
-
Byrd, J.C.1
Furman, R.R.2
Coutre, S.E.3
Flinn, I.W.4
Burger, J.A.5
Blum, K.A.6
-
7
-
-
84895785316
-
BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity
-
e-pub ahead of print 25 November 2013 doi:10.1038/leu.2013.358
-
Cheng S, Ma J, Guo A, Lu P, Leonard JP, Coleman M. et al. BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity. Leukemia 2013; e-pub ahead of print 25 November 2013; doi:10.1038/leu.2013.358.
-
(2013)
Leukemia
-
-
Cheng, S.1
Ma, J.2
Guo, A.3
Lu, P.4
Leonard, J.P.5
Coleman, M.6
-
8
-
-
80053345977
-
The phosphoinositide 30-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia
-
Hoellenriegel J, Meadows SA, Sivina M, Wierda WG, Kantarjian H, Keating MJ. et al. The phosphoinositide 30-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia. Blood 2011; 118: 3603-3612.
-
(2011)
Blood
, vol.118
, pp. 3603-3612
-
-
Hoellenriegel, J.1
Meadows, S.A.2
Sivina, M.3
Wierda, W.G.4
Kantarjian, H.5
Keating, M.J.6
-
9
-
-
84895796894
-
Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors
-
e-pub ahead of print 25 October 2013 doi:10.1038/leu.2013.311
-
Kharfan-Dabaja MA, Wierda WG, Cooper LJN. Immunotherapy for chronic lymphocytic leukemia in the era of BTK inhibitors. Leukemia 2013; e-pub ahead of print 25 October 2013; doi:10.1038/leu.2013.311.
-
(2013)
Leukemia
-
-
Kharfan-Dabaja, M.A.1
Wierda, W.G.2
Cooper, L.J.N.3
-
11
-
-
77957201023
-
Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals
-
Herman SE, Gordon AL, Wagner AJ, Heerema NA, Zhao W, Flynn JM. et al. Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals. Blood 2010; 116: 2078-2088.
-
(2010)
Blood
, vol.116
, pp. 2078-2088
-
-
Herman, S.E.1
Gordon, A.L.2
Wagner, A.J.3
Heerema, N.A.4
Zhao, W.5
Flynn, J.M.6
-
12
-
-
84878969076
-
SYK inhibition modulates distinct PI3K/AKT-dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas
-
Chen L, Monti S, Juszczynski P, Ouyang J, Chapuy B, Neuberg D. et al. SYK inhibition modulates distinct PI3K/AKT-dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomas. Cancer Cell 2013; 23: 826-838.
-
(2013)
Cancer Cell
, vol.23
, pp. 826-838
-
-
Chen, L.1
Monti, S.2
Juszczynski, P.3
Ouyang, J.4
Chapuy, B.5
Neuberg, D.6
-
13
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
Srinivasan L, Sasaki Y, Calado DP, Zhang B, Paik JH, DePinho RA. et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell 2009; 139: 573-586.
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
Sasaki, Y.2
Calado, D.P.3
Zhang, B.4
Paik, J.H.5
DePinho, R.A.6
|