Genetic and environmental origins of hypospadias

Current Opinion in Endocrinology, Diabetes and Obesity

Volumn 21, Issue 3, 2014, Pages 227-232

  Thorup, Jorgen ^a,b   Nordenskjöld, Agneta ^c,d   Hutson, John M ^e,f,g  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c KAROLINSKA INSTITUTE   (Sweden)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e ROYAL CHILDREN'S HOSPITAL   (Australia)

^f MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

environment; genes; hypospadias; placenta

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; ANDROGEN; ANDROGEN RECEPTOR; CHLORPHENOTANE; CHORIONIC GONADOTROPIN; ENDOCRINE DISRUPTOR; HEXACHLOROBENZENE; NEUROTENSIN RECEPTOR; ORGANOCHLORINE DERIVATIVE; ESTROGEN RECEPTOR ALPHA; POLLUTANT;

ANDROGEN DEFICIENCY; BIRTH WEIGHT; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL FACTOR; FEMINIZATION; FERTILIZATION IN VITRO; FIRST TRIMESTER PREGNANCY; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; HAPLOTYPE; HEREDITY; HERITABILITY; HUMAN; HYPOSPADIAS; HYPOTHESIS; LOW BIRTH WEIGHT; MATERNAL AGE; MATERNAL HYPERTENSION; NONHUMAN; OCCUPATIONAL EXPOSURE; PATHOGENESIS; PHENOTYPE; PLACENTA INSUFFICIENCY; POLLUTANT; PREECLAMPSIA; PRENATAL GROWTH; PREVALENCE; REVIEW; RISK ASSESSMENT; SEX DIFFERENTIATION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSACTIVATION; ADULT; DEFICIENCY; ETIOLOGY; FEMALE; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; MALE; METABOLISM; NEWBORN; PLACENTAL INSUFFICIENCY; PREGNANCY; PRENATAL EXPOSURE; RISK FACTOR;

ADULT; ANDROGENS; CHORIONIC GONADOTROPIN; ENVIRONMENTAL POLLUTANTS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPOSPADIAS; INFANT, NEWBORN; MALE; MATERNAL EXPOSURE; PLACENTAL INSUFFICIENCY; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS;

EID: 84899914425     PISSN: 1752296X     EISSN: 17522978     Source Type: Journal    
DOI: 10.1097/MED.0000000000000063     Document Type: Review

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