Enrichment and purification of six Aconitum alkaloids from Aconiti kusnezoffii radix by macroporous resins and quantification by HPLC-MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 960, Issue , 2014, Pages 174-181

  Liu, Jingjing ^a   Li, Qing ^a   Liu, Ran ^a   Yin, Yidi ^a   Chen, Xiaohui ^a   Bi, Kaishun ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aconitum; Enrichment; HPLC MS; Macroporous resins; Purification

Indexed keywords

ADSORPTION; ALKALOIDS; BLAST ENRICHMENT; DESORPTION; METABOLITES; PURIFICATION; RESINS;

ACONITUM; ADSORPTION AND DESORPTIONS; HPLC-MS; LARGE-SCALE PRODUCTION; MACROPOROUS RESIN; PERFORMANCE CHARACTERISTICS; SCIENTIFIC REFERENCES; TRADITIONAL CHINESE MEDICINE;

NITROGEN COMPOUNDS;

ACONITI KUSNEZOFFII EXTRACT; ACONITINE; ALCOHOL; ALKALOID DERIVATIVE; BENZOYLACONINE; BENZOYLHYPACONINE; BENZOYLMESACONINE; HYPACONITINE; MESACONITINE; PLANT MEDICINAL PRODUCT; RESIN; UNCLASSIFIED DRUG; ALKALOID; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PLANT EXTRACT;

ACONITE; ACONITI KUSNEZOFFII; ADSORPTION KINETICS; ARTICLE; CONCENTRATION (PARAMETERS); CORRELATION COEFFICIENT; DESORPTION; EQUILIBRIUM CONSTANT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LARGE SCALE PRODUCTION; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; ADSORPTION; CHEMISTRY; ISOLATION AND PURIFICATION; MASS SPECTROMETRY; POROSITY; PROCEDURES; REPRODUCIBILITY;

ACONITUM; ADSORPTION; ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN-ION CONCENTRATION; LABORATORY CHEMICALS; MASS SPECTROMETRY; PLANT EXTRACTS; POROSITY; REPRODUCIBILITY OF RESULTS;

EID: 84899908046     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.04.034     Document Type: Article

References (16)

1. Liang X.M., Jin Y., Wang Y.P., Jin G.W., Fu Q., Xiao Y.S. J. Chromatogr. A 2009, 1216(11):2035.
2. Wang Z., Wen J., Xing J.B., He Y. J. Pharm. Bio. A 2006, 40(4):1031.
3. Singhuber J., Zhu M., Prinz S., Kopp B. J. Ethnopharm. 2009, 126(1):18.
4. Voss L.J., Voss J.M., McLeay L., Sleigh J.W. Europ. J. Pharm. 2008, 584(2-3):291.
5. Wang J.S., Heijden R.V.D., Spruit S., Hankermeier T., Chan K., Greef J.V.D., Xu G.W., Wang M. J. Ethnopharm. 2009, 126(1):34.
6. Dickens P., Tai Y., But P., Tomlinson B., Ng H., Yan K. Forensic. Sci. Inter. 1994, 67(1):55.
7. Tai Y., Lau C., Young K., But P. Lancet 1992, 340(8830):1254.
8. Mizugaki M., Ito K., Ohyama Y., Konishi Y., Tanaka S., Kurasawa K. J. Anal. Toxicol. 1998, 22(4):336.
9. Zhao Z.Y., Dong L.L., Wu Y.L., Lin F. Food Bioprod. Process. 2011, 89(4):266.
10. Jia G.T., Lu X.Y. J. Chromatogr. A 2008, 1193(1-2):136.
11. Fu Y.J., Zu Y.G., Liu W., Efferth T., Zhang N.J., Liu X.N., Kong Y. J. Chromatogr. A 2006, 1137(2):145.
12. Ma C.Y., Tao G.J., Tang J., Lou Z.X., Wang H.X., Gu X.H., Hu L.M., Yin M.L. Separat. Purif. Technol. 2009, 69(1):22.
13. Liu W., Zhang S., Zu Y.G., Fu Y.J., Ma W., Zhang D.Y., Kong Y., Li X.J. Bioresour. Technol. 2010, 101(12):4667.
14. Zhu Z.Y., Wang B.L., Li J.S. Chin. J. Drug Anal. 1996, 16:154.
15. Sun A.M., Chen D.H., Bi P.X. Chin. J. Chromatogr. 1999, 17:67.
16. Xie Y., Jiang Z.H., Zhou H., Xu H.X., Liu L. J. Chromatogr. A 2005, 1093:195.