TCTP as therapeutic target in cancers

Cancer Treatment Reviews

Volumn 40, Issue 6, 2014, Pages 760-769

  Acunzo, Julie ^a,b,c,d   Baylot, Virginie ^a,b,c,d   So, Alan ^e   Rocchi, Palma ^a,b,c,d  

^a AIX MARSEILLE UNIVERSITY   (France)

^b INSTITUT PAOLI CALMETTES   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d CNRS   (France)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cancer; Inhibitory strategy; TCTP; Therapeutic target

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CELL CYCLE PROTEIN; CHLORPROMAZINE; FLUPENTIXOL; HYDROXYZINE; MESSENGER RNA; PAROXETINE; PERPHENAZINE; PHENOTHIAZINE; PROMETHAZINE; SERTRALINE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; THIORIDAZINE; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

BREAST CANCER; CELL DEATH; CELL GROWTH; CELL MATURATION; DNA DAMAGE; DNA REPAIR; HUMAN; IMMUNE SYSTEM; LUNG CANCER; NEOPLASM; NONHUMAN; NUCLEAR REPROGRAMMING; OXIDATIVE STRESS; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CANCER; INHIBITORY STRATEGY; TCTP; THERAPEUTIC TARGET;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL PROLIFERATION; FEMALE; HUMANS; MALE; MOLECULAR TARGETED THERAPY; NEOPLASMS; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84899906540     PISSN: 03057372     EISSN: 15321967     Source Type: Journal    
DOI: 10.1016/j.ctrv.2014.02.007     Document Type: Review

References (100)

1. Yenofsky R., et al. Regulation of messenger-Rna utilization in mouse erythroleukemia-cells induced to differentiate by exposure to dimethylsulfoxide. Mol Cell Biol 1983, 3(7):1197-1203.
2. Bommer U.A., Thiele B.J. The translationally controlled tumour protein (TCTP). Int J Biochem Cell Biol 2004, 36(3):379-385.
3. MacDonald S.M., et al. Molecular identification of an IgE-dependent histamine-releasing factor. Science 1995, 269(5224):688-690.
4. Amson R., et al. Reciprocal repression between P53 and TCTP. Nat Med 2012, 18(1):91-99.
5. Amson R., et al. TPT1/TCTP-regulated pathways in phenotypic reprogramming. Trends Cell Biol 2013, 23(1):37-46.
6. Tuynder M., et al. Translationally controlled tumor protein is a target of tumor reversion. Proc Natl Acad Sci U S A 2004, 101(43):15364-15369.
7. Nagano-Ito M., Ichikawa S. Biological effects of mammalian translationally controlled tumor protein (TCTP) on cell death, proliferation, and tumorigenesis. Biochem Res Int 2012, 2012:204960.
8. Miao X., et al. TCTP overexpression is associated with the development and progression of glioma. Tumour Biol 2013.
9. Stapleton H., Kirkham M., Thomas G. Qualitative study of evidence based leaflets in maternity care. BMJ 2002, 324(7338):639.
10. Thiele H., et al. Structure of the promoter and complete sequence of the gene coding for the rabbit translationally controlled tumor protein (TCTP) P23. Eur J Biochem 1998, 257(1):62-68.
11. Bommer U.A., et al. The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR. RNA 2002, 8(4):478-496.
12. Bohm H., et al. The growth-related protein P23 of the Ehrlich ascites tumor: translational control, cloning and primary structure. Biochem Int 1989, 19(2):277-286.
13. Thaw P., et al. Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat Struct Biol 2001, 8(8):701-704.
14. Lowther W.T., et al. The mirrored methionine sulfoxide reductases of Neisseria gonorrhoeae pilB. Nat Struct Biol 2002, 9(5):348-352.
15. Susini L., et al. TCTP protects from apoptotic cell death by antagonizing bax function. Cell Death Differ 2008, 15(8):1211-1220.
16. Cucchi U., et al. Phosphorylation of TCTP as a marker for polo-like kinase-1 activity in vivo. Anticancer Res 2010, 30(12):4973-4985.
17. Diraison F., et al. Translationally controlled tumour protein (TCTP) is a novel glucose-regulated protein that is important for survival of pancreatic beta cells. Diabetologia 2011, 54(2):368-379.
18. Gachet Y., et al. The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle. J Cell Sci 1999, 112(Pt 8):1257-1271.
19. Kim M., et al. Identification of the calcium binding sites in translationally controlled tumor protein. Arch Pharm Res 2000, 23(6):633-636.
20. Jung J., et al. Translationally controlled tumor protein interacts with the third cytoplasmic domain of Na, K-ATPase alpha subunit and inhibits the pump activity in HeLa cells. J Biol Chem 2004, 279(48):49868-49875.
21. Rho S.B., et al. Anti-apoptotic protein TCTP controls the stability of the tumor suppressor p53. FEBS Lett 2011, 585(1):29-35.
22. Chen Y., et al. Physical and functional antagonism between tumor suppressor protein p53 and fortilin, an anti-apoptotic protein. J Biol Chem 2011, 286(37):32575-32585.
23. Arcuri F., et al. Translationally controlled tumor protein (TCTP) in the human prostate and prostate cancer cells: expression, distribution, and calcium binding activity. Prostate 2004, 60(2):130-140.
24. Li F., Zhang D., Fujise K. Characterization of fortilin, a novel antiapoptotic protein. J Biol Chem 2001, 276(50):47542-47549.
25. Ma Y.P., Zhu W.L. Cytoplasmic and nuclear localization of TCTP in normal and cancer cells. Biochem Res Int 2012, 2012:871728.
26. Baylot V., et al. Targeting TCTP as a new therapeutic strategy in castration-resistant prostate cancer. Mol Ther 2012.
27. Rid R., et al. H2O2-dependent translocation of TCTP into the nucleus enables its interaction with VDR in human keratinocytes: TCTP as a further module in calcitriol signalling. J Steroid Biochem Mol Biol 2010, 118(1-2):29-40.
28. Amzallag N., et al. TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J Biol Chem 2004, 279(44):46104-46112.
29. Lespagnol A., et al. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ 2008, 15(11):1723-1733.
30. Andree H., et al. Expression of the human TPT1 gene coding for translationally controlled tumor protein (TCTP) is regulated by CREB transcription factors. Gene 2006, 380(2):95-103.
31. Chan T.H., et al. Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development. Hepatology 2012, 55(2):491-505.
32. Chen W., et al. Tumor protein translationally controlled 1 is a p53 target gene that promotes cell survival. Cell Cycle 2013, 12(14):2321-2328.
33. Kaarbo M., et al. TCTP is an androgen-regulated gene implicated in prostate cancer. PLoS One 2013, 8(7):e69398.
34. Walsh B.J., et al. Identification of macrophage activation associated proteins by two-dimensional gel electrophoresis and microsequencing. J Leukoc Biol 1995, 57(3):507-512.
35. Sinha P., et al. Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis. Electrophoresis 2000, 21(14):3048-3057.
36. Sturzenbaum S.R., Kille P., Morgan A.J. Identification of heavy metal induced changes in the expression patterns of the translationally controlled tumour protein (TCTP) in the earthworm Lumbricus rubellus1. Biochim Biophys Acta 1998, 1398(3):294-304.
37. Oikawa K., et al. Dioxin stimulates synthesis and secretion of IgE-dependent histamine-releasing factor. Biochem Biophys Res Commun 2002, 290(3):984-987.
38. Yenofsky R., Bergmann I., Brawerman G. Messenger-RNA species partially in a repressed state in mouse sarcoma ascites-cells. Proc Natl Acad Sci U S A-Biol Sci 1982, 79(19):5876-5880.
39. Bommer U.A., et al. Roles of the translationally controlled tumour protein (TCTP) and the double-stranded RNA-dependent protein kinase, PKR, in cellular stress responses. Oncogene 2010, 29(5):763-773.
40. Barber G.N. The dsRNA-dependent protein kinase, PKR and cell death. Cell Death Differ 2005, 12(6):563-570.
41. Garcia M.A., Meurs E.F., Esteban M. The dsRNA protein kinase PKR: virus and cell control. Biochimie 2007, 89(6-7):799-811.
42. Gingras A.C., Raught B., Sonenberg N. EIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annu Rev Biochem 1999, 68:913-963.
43. Bommer U.A., et al. Translational regulation of the mammalian growth-related protein P23: involvement of eIF-4E. Cell Mol Biol Res 1994, 40(7-8):633-641.
44. Meyuhas O. Synthesis of the translational apparatus is regulated at the translational level. Eur J Biochem 2000, 267(21):6321-6330.
45. Thomas G. The S6 kinase signaling pathway in the control of development and growth. Biol Res 2002, 35(2):305-313.
46. Ma X.X., et al. Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1. J Biol Chem 2011, 286(15):13430-13437.
47. Zhang D., et al. Physical and functional interaction between myeloid cell leukemia 1 protein (MCL1) and Fortilin. The potential role of MCL1 as a fortilin chaperone. J Biol Chem 2002, 277(40):37430-37438.
48. Chen S.H., et al. A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner. Mol Biol Cell 2007, 18(7):2525-2532.
49. Hsu Y.C., et al. Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase. Nature 2007, 445(7129):785-788.
50. Rehmann H., et al. Biochemical characterisation of TCTP questions its function as a guanine nucleotide exchange factor for Rheb. FEBS Lett 2008, 582(20):3005-3010.
51. Wang X., et al. Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling. J Biol Chem 2008, 283(45):30482-30492.
52. Yarm F.R. Plk phosphorylation regulates the microtubule-stabilizing protein TCTP. Mol Cell Biol 2002, 22(17):6209-6221.
53. Burgess A., et al. Chfr interacts and colocalizes with TCTP to the mitotic spindle. Oncogene 2008, 27(42):5554-5566.
54. Bazile F., et al. Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells. Carcinogenesis 2009, 30(4):555-565.
55. Langdon J.M., Vonakis B.M., MacDonald S.M. Identification of the interaction between the human recombinant histamine releasing factor/translationally controlled tumor protein and elongation factor-1 delta (also known as eElongation factor-1B beta). Biochim Biophys Acta 2004, 1688(3):232-236.
56. Kim M., Jung J., Lee K. Roles of ERK, PI3 kinase, and PLC-gamma pathways induced by overexpression of translationally controlled tumor protein in HeLa cells. Arch Biochem Biophys 2009, 485(1):82-87.
57. Liu H., et al. Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP. Mol Cell Biol 2005, 25(8):3117-3126.
58. Yang Y., et al. An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene 2005, 24(30):4778-4788.
59. Graidist P., Phongdara A., Fujise K. Antiapoptotic protein partners fortilin and MCL1 independently protect cells from 5-fluorouracil-induced cytotoxicity. J Biol Chem 2004, 279(39):40868-40875.
60. Joshi A., et al. Adamantinoma of tibial shaft. JNMA J Nepal Med Assoc 2009, 48(176):331-334.
61. Gnanasekar M., Dakshinamoorthy G., Ramaswamy K. Translationally controlled tumor protein is a novel heat shock protein with chaperone-like activity. Biochem Biophys Res Commun 2009, 386(2):333-337.
62. Bonnet C., et al. Identification and transcription control of fission yeast genes repressed by an ammonium starvation growth arrest. Yeast 2000, 16(1):23-33.
63. Rupec R.A., et al. Isolation of a hypoxia-induced cDNA with homology to the mammalian growth-related protein p23. Oncol Res 1998, 10(2):69-74.
64. Xu A., Bellamy A.R., Taylor J.A. Expression of translationally controlled tumour protein is regulated by calcium at both the transcriptional and post-transcriptional level. Biochem J 1999, 342(Pt 3):683-689.
65. Mak C.H., Su K.W., Ko R.C. Identification of some heat-induced genes of Trichinella spiralis. Parasitology 2001, 123(Pt 3):293-300.
66. Haghighat N.G., Ruben L. Purification of novel calcium binding proteins from Trypanosoma brucei: properties of 22-, 24- and 38-kilodalton proteins. Mol Biochem Parasitol 1992, 51(1):99-110.
67. Sanchez J.C., et al. Translationally controlled tumor protein: a protein identified in several nontumoral cells including erythrocytes. Electrophoresis 1997, 18(1):150-155.
68. Rao K.V., et al. Cloning and characterization of a calcium-binding, histamine-releasing protein from Schistosoma mansoni. J Biol Chem 2002, 277(34):31207-31213.
69. Graidist P., et al. Fortilin binds Ca2+ and blocks Ca2+-dependent apoptosis in vivo. Biochem J 2007, 408(2):181-191.
70. Greulich H., et al. Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2. Proc Natl Acad Sci U S A 2012, 109(36):14476-14481.
71. Bini L., et al. Protein expression profiles in human breast ductal carcinoma and histologically normal tissue. Electrophoresis 1997, 18(15):2832-2841.
72. Zhang J., et al. Role of the translationally controlled tumor protein in DNA damage sensing and repair. Proc Natl Acad Sci U S A 2012, 109(16):E926-E933.
73. Donovan P.J., Gearhart J. The end of the beginning for pluripotent stem cells. Nature 2001, 414(6859):92-97.
74. Scholer H.R., et al. A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor. EMBO J 1989, 8(9):2543-2550.
75. Monk M., Holding C. Human embryonic genes re-expressed in cancer cells. Oncogene 2001, 20(56):8085-8091.
76. Chambers I., et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003, 113(5):643-655.
77. Mitsui K., et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113(5):631-642.
78. Koziol M.J., Garrett N., Gurdon J.B. Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei. Curr Biol 2007, 17(9):801-807.
79. Tani T., et al. Bovine oocytes with the potential to reprogram somatic cell nuclei have a unique 23-kDa protein, phosphorylated transcriptionally controlled tumor protein (TCTP). Cloning Stem Cells 2007, 9(2):267-280.
80. Gidekel S., et al. Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 2003, 4(5):361-370.
81. MacDonald S.M., et al. Studies of IgE-dependent histamine releasing factors: heterogeneity of IgE. J Immunol 1987, 139(2):506-512.
82. Schroeder J.T., Lichtenstein L.M., MacDonald S.M. An immunoglobulin E-dependent recombinant histamine-releasing factor induces interleukin-4 secretion from human basophils. J Exp Med 1996, 183(3):1265-1270.
83. Schroeder J.T., Lichtenstein L.M., MacDonald S.M. Recombinant histamine-releasing factor enhances IgE-dependent IL-4 and IL-13 secretion by human basophils. J Immunol 1997, 159(1):447-452.
84. Wantke F., et al. The human recombinant histamine releasing factor: functional evidence that it does not bind to the IgE molecule. J Allergy Clin Immunol 1999, 103(4):642-648.
85. MacDonald S.M. Histamine-releasing factors. Curr Opin Immunol 1996, 8(6):778-783.
86. Bheekha-Escura R., et al. Human recombinant histamine-releasing factor activates human eosinophils and the eosinophilic cell line, AML14-3D10. Blood 2000, 96(6):2191-2198.
87. Kim M., et al. Dimerization of translationally controlled tumor protein is essential for its cytokine-like activity. PLoS One 2009, 4(7):e6464.
88. Kim M., et al. A peptide binding to dimerized translationally controlled tumor protein modulates allergic reactions. J Mol Med (Berl) 2011, 89(6):603-610.
89. Kang H.S., et al. Molecular identification of IgE-dependent histamine-releasing factor as a B cell growth factor. J Immunol 2001, 166(11):6545-6554.
90. Yoneda K., et al. Stimulation of human bronchial epithelial cells by IgE-dependent histamine-releasing factor. Am J Physiol Lung Cell Mol Physiol 2004, 286(1):L174-L181.
91. van Soest R.J., et al. Initial biopsy Gleason score as a predictive marker for survival benefit in patients with castration-resistant prostate cancer treated with docetaxel: data from the tax327 study. Eur Urol 2013.
92. Deng S.S., et al. Comparative proteome analysis of breast cancer and adjacent normal breast tissues in human. Genomics Proteomics Bioinformatics 2006, 4(3):165-172.
93. Jung J., et al. Translationally controlled tumor protein induces human breast epithelial cell transformation through the activation of Src. Oncogene 2011, 30(19):2264-2274.
94. Tuynder M., et al. Biological models and genes of tumor reversion: cellular reprogramming through tpt1/TCTP and SIAH-1. Proc Natl Acad Sci U S A 2002, 99(23):14976-14981.
95. Kim J.E., et al. Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model. Exp Mol Med 2008, 40(6):709-720.
96. Chung S., et al. Expression of translationally controlled tumor protein mRNA in human colon cancer. Cancer Lett 2000, 156(2):185-190.
97. Zhu W.L., et al. Messenger RNA expression of translationally controlled tumor protein (TCTP) in liver regeneration and cancer. Anticancer Res 2008, 28(3A):1575-1580.
98. Bull V.H., et al. Temporal proteome profiling of taxol-induced mitotic arrest and apoptosis. Electrophoresis 2010, 31(11):1873-1885.
99. Ge F., et al. Quantitative proteomic analysis of tumor reversion in multiple myeloma cells. J Proteome Res 2011, 10(2):845-855.
100. Ma Q., et al. The role of translationally controlled tumor protein in tumor growth and metastasis of colon adenocarcinoma cells. J Proteome Res 2010, 9(1):40-49.