Expression and purification of chaperone-active recombinant clusterin

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Dabbs, Rebecca A ^a   Wilson, Mark R ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CLUSTERIN; RECOMBINANT PROTEIN;

ALPHA CHAIN; ANIMAL CELL; ANTIBODY AFFINITY; ARTICLE; BETA CHAIN; CATION EXCHANGE; CONTROLLED STUDY; ESCHERICHIA COLI; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; NONHUMAN; PREDICTION; PROCESS DEVELOPMENT; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN SECRETION; VALIDATION PROCESS;

CHROMATOGRAPHY, GEL; CLUSTERIN; GLUTATHIONE TRANSFERASE; GLYCOSYLATION; HUMANS; MOLECULAR CHAPERONES; MUTATION; PROTEIN BINDING; RECOMBINANT PROTEINS;

EID: 84899894134     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086989     Document Type: Article

References (29)

1. Humphreys DT, Carver JA, Easterbrook-Smith SB, Wilson MR (1999) Clusterin has chaperone-like activity similar to that of small heat shock proteins. J Biol Chem 274: 6875-6881.
2. Wyatt AR, Yerbury JJ, Berghofer P, Greguric I, Katsifis A, et al. (2011) Clusterin facilitates in vivo clearance of extracellular misfolded proteins. Cell Mol Life Sci 68: 3919-3931.
3. Yerbury JJ, Stewart EM, Wyatt AR, Wilson MR (2005) Quality control of protein folding in extracellular space. EMBO Rep 6: 1131-1136. (Pubitemid 41741695)
4. Poon S, Treweek TM, Wilson MR, Easterbrook-Smith SB (2002) Clusterin is an extracellular chaperone that specifically interacts with slowly aggregating proteins on their off-folding pathway. FEBS Letters 513: 259-266. (Pubitemid 34251275)
5. Yerbury JJ, Poon S, Meehan S, Thompson B, Kumita JR, et al. (2007) The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures. FASEB J 21: 2312-2322. (Pubitemid 47230661)
6. Hatters DM, Wilson MR, Easterbrook-Smith SB, Howlett GJ (2002) Suppression of apolipoprotein C-II amyloid formation by the extracellular chaperone, clusterin. Eur J Biochem 269: 2789-2794. (Pubitemid 34595647)
7. Oda T, Osterberg HH, Johnson SA, Pasinetti GM, Morgan TE, et al. (1995) Clusterin (apoJ) alters the aggregation of amyloid beta peptide 1-42 and forms slowly sedimenting A-beta complexes that cause oxidative stress. Exp Neurol 136: 22-31.
8. Wyatt AR, Yerbury JJ, Ecroyd H, Wilson MR (2013) Extracellular chaperones and proteostasis. Annu Rev Biochem 82: 295-322.
9. Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41: 1088-1093.
10. Lambert JC, Heath S, Even G, Campion D, Sleegers K, et al. (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41: 1094-1099.
11. Narayan P, Orte A, Clarke RW, Bolognesi B, Hook S, et al. (2012) The extracellular chaperone clusterin sequesters oligomeric forms of the amyloidbeta(1-40) peptide. Nat Struct Mol Biol 19: 79-83.
12. Nizard P, Tetley S, Le Drean Y, Watrin T, Le Goff P, et al. (2007) Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol. Traffic 8: 554-565. (Pubitemid 46638565)
13. Li N, Zoubeidi A, Beraldi E, Gleave ME (2013) GRP78 regulates clusterin stability, retrotranslocation and mitochondrial localization under ER stress in prostate cancer. Oncogene 32: 1933-1942.
14. Stewart EM, Aquilina JA, Easterbrook-Smith SB, Murphy-Durland D, Jacobsen C, et al. (2007) Effects of glycosylation on the structure and function of the extracellular chaperone clusterin. Biochemistry 46: 1412-1422. (Pubitemid 46208489)
15. Kapron JT, Hilliard GM, Lakins JN, Tenniswood MP, West KA, et al. (1997) Identification and characterization of glycosylation sites in human serum clusterin. Protein Sci 6: 2120-2133. (Pubitemid 27449292)
16. Wilson MR, Easterbrook-Smith SB (2000) Clusterin is a secreted mammalian chaperone. Trends Biochem Sci 25: 95-98. (Pubitemid 30122416)
17. Lakins JN, Poon S, Easterbrook-Smith SB, Carver JA, Tenniswood MP, et al. (2002) Evidence that clusterin has discrete chaperone and ligand binding sites. Biochemistry 41: 282-291. (Pubitemid 34049405)
18. Choi-Miura NH, Takahashi Y, Nakano Y, Tobe T, Tomita M (1992) Identification of the disulfide bonds in human plasma protein SP-40,40 (apolipoprotein-J). J Biochem 112: 557-561.
19. Stewart EM (2007) Structural and functional characterisation of the extracellular chaperone clusterin: University of Wollongong.
20. Bajari TM, Strasser V, Nimpf J, Schneider WJ (2003) A model for modulation of leptin activity by association with clusterin. FASEB J 17: 1505-1507.
21. Heller AR, Fiedler F, Braun P, Stehr SN, Bodeker H, et al. (2003) Clusterin protects the lung from leukocyte-induced injury. Shock 20: 166-170.
22. Hakkoum D, Imhof A, Vallet PG, Boze H, Moulin G, et al. (2008) Clusterin increases post-ischemic damages in organotypic hippocampal slice cultures. J Neurochem 106: 1791-1803.
23. Boggs LN, Fuson KS, Baez M, Churgay L, McClure D, et al. (1996) Clusterin (Apo J) protects against in vitro amyloid-beta (1-40) neurotoxicity. J Neurochem 67: 1324-1327. (Pubitemid 26277948)
24. Guan Q, Li S, Yip G, Gleave ME, Nguan CY, et al. (2012) Decrease in donor heart injury by recombinant clusterin protein in cold preservation with University of Wisconsin solution. Surgery 151: 364-371.
25. Ma X, Luo X, Zhu X, Li Z, Li H (2013) Purification and characterization of secretory clusterin proteins from an eukaryotic expression system and the preliminary exploration of its functions. Tumor 33: 597-603.
26. Humphreys D, Hochgrebe TT, Easterbrook-Smith SB, Tenniswood MP, Wilson MR (1997) Effects of clusterin overexpression on TNFalpha- and TGFbeta-mediated death of L929 cells. Biochemistry 36: 15233-15243. (Pubitemid 27527988)
27. Wyatt AR, Yerbury JJ, Wilson MR (2009) Structural characterization of clusterin-chaperone client protein complexes. J Biol Chem 284: 21920-21927.
28. Blaschuk O, Burdzy K, Fritz IB (1983) Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid. J Biol Chem 258: 7714-7720. (Pubitemid 13038010)
29. Carver JA, Rekas A, Thorn DC, Wilson MR (2003) Small heat-shock proteins and clusterin: intra- and extracellular molecular chaperones with a common mechanism of action and function? IUBMB Life 55: 661-668. (Pubitemid 38116418)