Incompatibility of croscarmellose sodium with alkaline excipients in a tablet formulation

Pharmaceutical Development and Technology

Volumn 19, Issue 3, 2014, Pages 285-289

  Bindra, Dilbir S ^a   Stein, Daniel ^a   Pandey, Preetanshu ^a   Barbour, Nancy ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Alkalinity; Croscarmellose sodium; Dissolution slowdown; Gel formation; Hydrolysis; Slurry pH; Wet granulation

Indexed keywords

CROSCARMELLOSE SODIUM; EXCIPIENT;

ALKALINITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CROSS LINKING; DRUG HYDROLYSIS; DRUG INCOMPATIBILITY; DRUG SOLUBILITY; DRUG STABILITY; PH; PRIORITY JOURNAL; TABLET FORMULATION;

CARBOXYMETHYLCELLULOSE SODIUM; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; EXCIPIENTS; GELS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; POVIDONE; SOLUBILITY; TABLETS;

EID: 84899888297     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2013.778869     Document Type: Article

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