AT1 receptor blockade attenuates insulin resistance and myocardial remodeling in rats with diet-induced obesity

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Oliveira Junior, Silvio A ^a,b   Martinez, Paula F ^a,b   Guizoni, Danielle M ^a   Campos, Dijon H S ^a   Fernandes, Tiago ^c   Oliveira, Edilamar M ^c   Okoshi, Marina P ^a   Okoshi, Katashi ^a   Padovani, Carlos R ^a   Cicogna, Antonio C ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBUNIT BETA; LEPTIN; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN HEAVY CHAIN; PHOSPHATIDYLINOSITOL 3 KINASE; STRESS ACTIVATED PROTEIN KINASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC INTAKE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DRUG EFFECT; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; FIBROSING ALVEOLITIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE TEST; HEART VENTRICLE HYPERTROPHY; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; MALE; MORPHOMETRICS; NONHUMAN; OBESITY; RAT; RECEPTOR BLOCKING; SYSTOLIC BLOOD PRESSURE; WESTERN BLOTTING; WISTAR KYOTO RAT;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSINS; ANIMALS; BLOOD GLUCOSE; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; ENERGY INTAKE; INSULIN RESISTANCE; LOSARTAN; MALE; MAP KINASE SIGNALING SYSTEM; MYOCARDIUM; MYOSIN HEAVY CHAINS; OBESITY; RATS; RATS, INBRED WKY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, INSULIN; VENTRICULAR REMODELING;

EID: 84899878605     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086447     Document Type: Article

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