Extracellular matrix sub-types and mechanical stretch impact human cardiac fibroblast responses to transforming growth factor beta

Connective Tissue Research

Volumn 55, Issue 3, 2014, Pages 248-256

  Watson, Chris J ^a,b   Phelan, Dermot ^a,b   Collier, Patrick ^a,b   Horgan, Stephen ^a,b   Glezeva, Nadia ^a,b   Cooke, Gordon ^a,b   Xu, Maojia ^a,b   Ledwidge, Mark ^a,b   Mcdonald, Kenneth ^a,b   Baugh, John A ^a,b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b ST MICHAEL'S HOSPITAL   (Ireland)

Author keywords

Cardiac fibroblast; Collagen; Extracellular matrix; Mechanical stretch; Transforming growth factor beta

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; COLLAGEN TYPE 6; LAMININ; MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA1; COLLAGEN; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROBLAST; GENE EXPRESSION; HEART; HEART MUSCLE FIBROSIS; HEMODYNAMICS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MECHANICAL STRESS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; CELL CULTURE; CONNECTIVE TISSUE; METABOLISM;

CELLS, CULTURED; COLLAGEN; CONNECTIVE TISSUE; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; HUMANS; LAMININ; STRESS, MECHANICAL; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899864951     PISSN: 03008207     EISSN: 16078438     Source Type: Journal    
DOI: 10.3109/03008207.2014.904856     Document Type: Article

References (40)

1. Weber KT, Sun Y, Tyagi SC, Cleutjens JP. Collagen network of the myocardium: Function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol 1994;26:279-92.
2. Berrier AL, Yamada KM. Cell-matrix adhesion. J Cell Physiol 2007;213:565-73.
3. Huang C, Ogawa R. Fibroproliferative disorders and their mechanobiology. Connect Tissue Res 2012;53:187-96.
4. Fan D, Takawale A, Lee J, Kassiri Z. Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease. Fibrogenesis Tissue Repair 2012;5:15-20.
5. Kenchaiah S, Pfeffer MA. Cardiac remodeling in systemic hypertension. Med Clin North Am 2004;88:115-30.
6. Brown RD, Mitchell MD, Long CS. Proinflammatory cytokines and cardiac extracellular matrix: Regulation of fibroblast phenotype. In: Villareal FJ, ed. Interstitial fibrosis in heart failure. New York: Springer; 2004:57-81.
7. Brown RD, Ambler SK, Mitchell MD, Long CS. The cardiac fibroblast: Therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 2005;45:657-87.
8. Gallagher AM, Bahnson TD, Yu H, Kim NN, Printz MP. Species variability in angiotensin receptor expression by cultured cardiac fibroblasts and the infarcted heart. Am J Physiol 1998;274:H801-9.
9. Lijnen P, Petrov V. Transforming growth factor-beta 1-induced collagen production in cultures of cardiac fibroblasts is the result of the appearance of myofibroblasts. Methods Find Exp Clin Pharmacol 2002;24:333-44.
10. Lijnen PJ, Petrov VV, Fagard RH. Induction of cardiac fibrosis by transforming growth factor-beta(1). Mol Genet Metab 2000;71: 418-35.
11. Bujak M, Frangogiannis NG. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res 2007;74:184-95.
12. Vaughan MB, Howard EW, Tomasek JJ. Transforming growth factor-beta1 promotes the morphological and functional differentiation of the myofibroblast. Exp Cell Res 2000;257:180-9.
13. Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG. Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-beta. J Clin Invest 2010;120:3520-9.
14. Ignotz RA, Massague J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986;261:4337-45.
15. Thiele BJ, Doller A, Kahne T, Pregla R, Hetzer R, Regitz-Zagrosek V. RNA-binding proteins heterogeneous nuclear ribonucleoprotein A1, E1, and K are involved in post-Transcriptional control of collagen I and III synthesis. Circ Res 2004;95:1058-66.
16. van Nieuwenhoven FA, Hemmings KE, Porter KE, Turner NA. Combined effects of interleukin-1alpha and transforming growth factor-beta1 on modulation of human cardiac fibroblast function. Matrix Biol 2013;32:399-406.
17. Bissell MJ, Hall HG, Parry G. How does the extracellular matrix direct gene expression? J Theor Biol 1982;99:31-68.
18. He Y, Grinnell F. Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway. J Cell Biol 1994;126:457-64.
19. Rhee S, Jiang H, Ho CH, Grinnell F. Microtubule function in fibroblast spreading is modulated according to the tension state of cell-matrix interactions. Proc Natl Acad Sci USA 2007;104: 5425-30.
20. Petroll WM, Vishwanath M, Ma L. Corneal fibroblasts respond rapidly to changes in local mechanical stress. Invest Ophthalmol Vis Sci 2004;45:3466-74.
21. Mizutani T, Haga H, Kawabata K. Cellular stiffness response to external deformation: Tensional homeostasis in a single fibroblast. Cell Motil Cytoskeleton 2004;59:242-8.
22. Kaneko D, Sasazaki Y, Kikuchi T, Ono T, Nemoto K, Matsumoto H, Toyama Y. Temporal effects of cyclic stretching on distribution and gene expression of integrin and cytoskeleton by ligament fibroblasts in vitro. Connect Tissue Res 2009;50:263-9.
23. MacKenna DA, Dolfi F, Vuori K, Ruoslahti E. Extracellular signalregulated kinase and c-Jun NH2-Terminal kinase activation by mechanical stretch is integrin-dependent and matrix-specific in rat cardiac fibroblasts. J Clin Invest 1998;101:301-10.
24. Wilson E, Sudhir K, Ives HE. Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/ integrin interactions. J Clin Invest 1995;96:2364-72.
25. Spiro MJ, Crowley TJ. Increased rat myocardial type VI collagen in diabetes mellitus and hypertension. Diabetologia 1993;36:93-8.
26. Naugle JE, Olson ER, Zhang X, Mase SE, Pilati CF, Maron MB, Folkesson HG, Horne WI, Doane KJ, Meszaros JG. Type VI collagen induces cardiac myofibroblast differentiation: Implications for postinfarction remodeling. Am J Physiol Heart Circ Physiol 2006;290:H323-30.
27. Schaper J, Kostin S, Hein S, Elsasser A, Arnon E, Zimmermann R. Structural remodelling in heart failure. Exp Clin Cardiol 2002;7: 64-8.
28. Butcher DT, Alliston T, Weaver VM. A tense situation: Forcing tumour progression. Nat Rev Cancer 2009;9:108-22.
29. Wipff PJ, Rifkin DB, Meister JJ, Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J Cell Biol 2007;179:1311-23.
30. Lutz R, Sakai T, Chiquet M. Pericellular fibronectin is required for RhoA-dependent responses to cyclic strain in fibroblasts. J Cell Sci 2010;123:1511-21.
31. Lee AA, Delhaas T, McCulloch AD, Villarreal FJ. Differential responses of adult cardiac fibroblasts to in vitro biaxial strain patterns. J Mol Cell Cardiol 1999;31:1833-43.
32. Butt RP, Bishop JE. Mechanical load enhances the stimulatory effect of serum growth factors on cardiac fibroblast procollagen synthesis. J Mol Cell Cardiol 1997;29:1141-51.
33. Carver W, Nagpal ML, Nachtigal M, Borg TK, Terracio L. Collagen expression in mechanically stimulated cardiac fibroblasts. Circ Res 1991;69:116-22.
34. Husse B, Briest W, Homagk L, Isenberg G, Gekle M. Cyclical mechanical stretch modulates expression of collagen I and collagen III by PKC and tyrosine kinase in cardiac fibroblasts. Am J Physiol Regul Integr Comp Physiol 2007;293:R1898-907.
35. Kolpakov V, Rekhter MD, Gordon D, Wang WH, Kulik TJ. Effect of mechanical forces on growth and matrix protein synthesis in the in vitro pulmonary artery. Analysis of the role of individual cell types. Circ Res 1995;77:823-31.
36. Kollros PR, Bates SR, Mathews MB, Horwitz AL, Glagov S. Cyclic AMP inhibits increased collagen production by cyclically stretched smooth muscle cells. Lab Invest 1987;56:410-17.
37. Dalla Costa AP, Clemente CF, Carvalho HF, Carvalheira JB, Nadruz Jr. W, Franchini KG. FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex. Cardiovasc Res 2010;86:421-31.
38. Geiger B, Spatz JP, Bershadsky AD. Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol 2009;10:21-33.
39. Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 2002;3:349-63.
40. Watson CJ, Phelan D, Xu M, Collier P, Neary R, Smolenski A, Ledwidge M, McDonald K, Baugh J. Mechanical stretch up-regulates the B-Type natriuretic peptide system in human cardiac fibroblasts: A possible defense against transforming growth factorbeta mediated fibrosis. Fibrogenesis Tissue Repair 2012;5:9-16.