Comparison of the needs for biodosimetry for large-scale radiation events for military versus civilian populations

Health Physics

Volumn 106, Issue 6, 2014, Pages 755-763

  Swartz, Harold M ^a   Flood, Ann Barry ^a   Williams, Benjamin B ^a   Meineke, Viktor ^b   Dörr, Harald ^b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

Accidents; Dosimetry; Handling; Nuclear; Radiation damage

Indexed keywords

CIVIL DEFENSE; COMPARATIVE STUDY; CONFERENCE PAPER; ENVIRONMENTAL EXPOSURE; HUMAN; LEUKOCYTE COUNT; MASS DISASTER; METHODOLOGY; NUCLEAR ACCIDENT; PROBABILITY; RADIOMETRY; SOLDIER;

CIVIL DEFENSE; ENVIRONMENTAL EXPOSURE; HUMANS; LEUKOCYTE COUNT; MASS CASUALTY INCIDENTS; MILITARY PERSONNEL; PROBABILITY; RADIOACTIVE HAZARD RELEASE; RADIOMETRY;

EID: 84899832340     PISSN: 00179078     EISSN: 15385159     Source Type: Journal    
DOI: 10.1097/HP.0000000000000069     Document Type: Conference Paper

References (44)

1. Ainsbury EA, Bakhanova E, Barquinero JF, Brai M, Chumak V, Correcher V, Darroudi F, Fattibene P, Gruel G, Guclu I, Horn S, Jaworska A, Kulka U, Lindholm C, Lloyd D, Longo A, Marrale M, Monteiro Gi O, Oestreicher U, Pajic J, Rakic B, Romm H, Trompier F, Veronese I, Voisin P, Vral A, Whitehouse CA, Wieser A, Woda C, Wojcik A, Rothkamm K. Review of retrospective dosimetry techniques for external ionising radiation exposures. Radiat Protect Dosim 147:573-592; 2011
2. Avondoglio D, Scott T, Kil WJ, Sproull M, Tofilon PJ, Camphausen K. High throughput evaluation of H2AX. Radiat Oncol24:4-3; 2009. DOI:10.1186/1748-717X- 4-31
3. Black PJ, Swarts SG. Ex vivo analysis of irradiated fingernails: chemical yields and properties of radiation-induced and mechanically-induced radicals. Health Phys 98:301-308; 2010. DOI:10.1097/HP.0b013e3181b0c045
4. BlakelyWF. Multiple parameter biodosimetry of exposed workers from the JCO criticality accident in Tokai-mura. J Radiol Protect 22:5; 2002. DOI:10.1088/0952-4746/22/1/003
5. Buddemeier BR, Dillon MB. Key response planning factors for the aftermath of nuclear terrorism. Berkeley, CA: Lawrence Livermore National Laboratory; LLNL-TR-410067; 2009
6. Buddemeier BR. Reducing the consequences of a nuclear detonation: recent research. Bridge40:28-38; 2010. Available at www.nae.edu/Publications/Bridge/ 19804/19920.aspx. Accessed 7 August 2013
7. Coleman CN, Knebel AR, Hick JL, Weinstock DM, Casagrande R, Caro JJ, DeRenzo EG, Dodgen D, Norwood AE, Sherman SE, Cliffer KD, McNally R, Bader JL, Murrain-Hill P. Scarce resources for nuclear detonation: project overview and challenges. Disaster Med Public Health Preparedness 5: S13-S19; 2011a
8. Coleman CN, Weinstock DM, Casagrande R, Hick JL, Bader JL, Chang F, Nemhauser JB, Knebel AR. Triage and treatment tools for use in a scarce resources-crisis standards of care setting after a nuclear detonation. Disaster Med Public Health Preparedness 5:S111-S121; 2011b. DOI:10.1001/ dmp.2011.22
9. Coy SL, Cheema AK, Tyburski JB, Laiakis EC, Collins SP, Fornace AJr. Radiation metabolomics and its potential in biodosimetry. Int J Radiat Biol 87:802-823; 2011
10. Desrosiers M, Schauer D. Electron paramagnetic resonance (EPR) biodosimetry. Nucl Instrum Meth B 184:219-228; 2001. DOI:10.1016/S0168-583X(01) 00614-0
11. DeWitt R, Klein D, Yukihara E, Simon S, McKeever S. Optically stimulated luminescence (OSL) of tooth enamel and its potential use in post-radiation exposure triage. Health Phys 98:432-439; 2010. DOI:10.1097/01.HP.0000347997. 57654.17
12. Fattibene P, Callens F. EPR dosimetry with tooth enamel: a review. Appl Radiat Isot 68:2033-2116; 2010. DOI:10.1016/ j.apradiso.2010.05.016
13. Fenech M.Current status, new frontiers and challenges in radiation biodosimetry using cytogenetic, transcriptomic and proteomic technologies. Radiat Meas 46:737-741; 2011. DOI:10.1016/j.radmeas.2011.01.016
14. Fenech M, Kirsch-Volders M, Rossnerova A, Sram R, Romm H, Bolognesi C, Ramakumar A, Soussaline F, Schunck C, Elhajouji A, AnwarW, Bonassi S. HUMN project initiative and review of validation, quality control and prospects for further development of automated micronucleus assays using image cytometry systems. Int J Hyg Envir Heal 216:541-552; 2013
15. Flegal FN, Devantier Y, Marro L, Wilkins RC. Validation of quickscan dicentric chromosome analysis for high throughput radiation biological dosimetry. Health Phys 102: 143-153; 2012
16. Flood AB, Nicolalde RJ, Demidenko E, Williams BB, Shapiro A, Wiley ALJr, Swartz HM. A framework for comparative evaluation of dosimetric methods to triage a large population following a radiological event. Radiat Meas 46:916-922; 2011. DOI:10.1016/j.radmeas.2011.02.019
17. Flood AB, Nicolalde RJ, Williams BB, Demidenko E, Evans J, Greene MA, Swartz HM. Comparative evaluation of dosimetric methods for triage in large-scale radiation events. Paper 34: MP-HFM223 34. In: Proceedings STO-MP-HFM 223: NATO Symposiumon Biological Effects of Ionizing Radiation Exposure and Countermeasures: Current Status and Future Perspectives. Ljubljana, Slovenia. Neuilly Sur Seine Cedex, France: NATO; 2012; 34:1-16. Available at http://www.cso.nato.int/abstracts. aspx RestrictRDP=4. Accessed 28 October 2013
18. Garty G, Chen Y, Salerno A, Turner H, Zhang J, Lyulko O, Bertucci A, Xu Y, Wang H, Simaan N. The RABIT: a rapid automated biodosimetry tool for radiological triage. Health Phys 98:209-217; 2010. DOI:10.1097/HP. 0b013e3181ab3cb6
19. Grace MB, Moyer BR, Prasher J, Cliffer KD, Ramakrishna N, Kaminski J, Coleman CN, Manning RG, Maidment BW, Hatchett R. Rapid radiation dose assessment for radiological public health emergencies: roles of NIAID and BARDA. Health Phys 98:172-178; 2010. DOI:10.1097/01.HP.0000348001.60905.c0
20. Knebel AR, Coleman CN, Cliffer KD,Murrain-Hill PM, McNally R, Oancea V, Jacobs J, Buddemeier B, Hick JL, Weinstock DM, Hrdina CM, Taylor T, Matzo M, Bader JL, Livinski AA, Parker G, Yeskey K. Allocation of scarce resources after a nuclear detonation: setting the context. Disaster Med Public Health Prep. 5:S20-S31; 2011
21. Marchetti F, Coleman MA, Jones IM, Wyrobek AJ. Candidate protein biodosimeters of human exposure to ionizing radiation. Int J Radiat Biol 82:605-639; 2006
22. McNamee JP, Flegal FN, Green HB, Marro L, Wilkins RC. Validation of the cytokinesis-block micronucleus (CBMN) assay for use as a triage biological dosimetry tool. Radiat Protect Dosim 135:232-242; 2009
23. National Security Staff. Interagency Policy Coordination Subcommittee for Preparedness and Response to Radiological and Nuclear Events. U.S. Executive Office of the President. Planning guidance for reaction to a nuclear detonation. Washington, DC: Executive Office of the President, National Security Council (NSC); 2010. Available at: http:// hps.org/homeland/documents/Planning-Guidance- for- Response-to-a-Nuclear-Detonation-2nd-Edition-FINAL.pdf. Accessed 10 September 2013
24. Paul S, Amundson SA. Development of gene expression signatures for practical radiation biodosimetry. Int J Radiat Oncol Biol Phys 71:1236-1244; 2008
25. Pinto MM, Santos NF, Amaral A. Current status of biodosimetry based on standard cytogenetic methods. Radiat Environ Bioph 49:567-581; 2010
26. Pouget JP, Laurent C, Delbos M, Benderitter M, Clairand I, Trompier F, Stephanazzi J, Carsin H, Lambert F, Voisin P, Gourmelon P. PCC-FISH in skin fibroblasts for local dose assessment: biodosimetric analysis of a victim of the Georgian radiological accident. Radiat Res 162:365-376; 2004
27. RieckeA, Ruf C, MeinekeV. Assessment of radiation damage: the need for a multiparametric and integrative approach with the help of both clinical and biological dosimetry. Health Phys 98:160-167; 2010. DOI:10.1097/HP. 0b013e3181b97306
28. Romm H, Wilkins RC, Coleman CN, Lillis-Hearne PK, Pellmar TC, Livingston GK, Awa AA, Jenkins MS, Yoshida MA, Oestreicher U, Prasanna PG. Biological dosimetry by the triage dicentric chromosome assay: potential implications for treatment of acute radiation syndrome in radiological mass casualties. Radiat Res175:397-404; 2011
29. Rossnerova A, Spatova M, Schunck C, Sram R. Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure. Mutagenesis26:169-175; 2011
30. Rothkamm K, Beinke C, Romm H, Badie C, Balagurunathan Y, Barnard S, Bernard N, Boulay-Greene H, Brengues M, De Amicis A, De Sanctis S, Greither R, Herodin F, Jones A, Kabacik S, Knie T, Kulka U, Lista F, Martigne P, Missell A, Moquet J, Oestreicher U, Peinnequin A, Poyot T, Roessler U, Scherthan H, Terbrueggen B, Thierens H, ValenteM, Vral A, Zenhausern F, Meineke V, Braselmann H, Abend M. Comparison of established and emerging biodosimetry assays. Radiat Res180:111-119; 2013
31. Sholom S, DeWitt R, Simon S, Bouville A, McKeever S. Emergency optically stimulated luminescence dosimetry using different materials. Radiat Meas 46:1866-1869; 2011. DOI:10.1016/ j.radmeas.2011.03.004
32. Swartz HM, Williams BB, Nicolalde RJ, Demidenko E, Flood AB. Overview of biodosimetry for management of unplanned exposures to ionizing radiation. Radiat Meas 46:742-748; 2011. DOI:10.1016/j.radmeas.2011.03.011
33. Swartz HM, Williams BB, Swarts SG, He X, Flood AB, Grinberg O, Sidabras J. Use of EPR dosimetry for field deployable triage for a large radiation event. HFM 223 Symposium on Biological Effects of Ionizing Radiation Exposure and Countermeasures: Current Status and Future Perspectives, Ljubljana, Slovenia, 8-10 October 2012. Oak Ridge, TN: Oak Ridge Associated Universities; 2012. Available at http://www. cso.nato.int/abstracts.aspx. Accessed 12 September 2013
34. Swartz HM, Flood AB, Williams BB, Nicolalde RJ, Shapiro A. Overview of methods for establishing dose to individuals for managing large-scale, unplanned, clinically significant exposures to ionizing radiation. In: The medical basis for radiation-accident preparedness. Proceedings of 5th REACTS International Symposium. ORAU 12 1771; 2013: 91-108
35. Straume T, Langlois RG, Lucas J, Jensen RH, BigbeeWL, Ramalho AT, Brandao-Mello CE. Novel biodosimetry methods applied to victims of the Goiania accident. Livermore, CA: Environmental Division, Lawrence Livermore National Laboratory; 1991
36. Symons MC, Chandra H, Wyatt JL. Electron paramagnetic resonance spectra of irradiated finger-nails: a possible measure of accidental exposure. Radiat Protect Dosim 58:11-15; 1995
37. Tawn EJ, Whitehouse CA, Riddell AE. FISH chromosome analysis of plutonium workers from the Sellafield nuclear facility. Radiat Res 165:592-597; 2006
38. Trompier F, Romanyukha A, Kornak L, Calas C, LeBlanc B, Mitchell C, Swartz H, Clairand I. Electron paramagnetic resonance radiation dosimetry in fingernails. Radiat Meas 44:6-10; 2009. DOI:10.1016/j.radmeas.2008.10.005
39. Turner HC, Brenner DJ, Chen Y, Bertucci A, Zhang J, Wang H, Lyulko OV, Xu Y, Shuryak I, Schaefer J, Simaan N, Randers-Pehrson G, Lawrence-Yao Y, Amundson SA, Garte G. Adapting the -H2AX assay for automated processing in human lymphocytes. 1. Technological aspects. Radiat Res 175:282-290; 2011
40. Vaurijoux A, Gruel G, Pouzoulet F, Gregoire E, Martin C, Roch-Lefevre S,Voisin P, Voisin P, Roy L. Strategy for population triage based on dicentric analysis. Radiat Res 171:541-548; 2009
41. Wilcox DE, He X, Gui J, Ruuge AE, Li H, Williams BB, Swartz HM. Dosimetry based on EPR spectral analysis of fingernail clippings. Health Phys98:309-317; 2010. DOI:10.1097/ HP.0b013e3181b27502
42. Williams BB, Dong R, Flood AB, Grinberg O, Kmiec M, Lesniewski PN, Matthews TP, Nicolalde RJ, Raynolds T, Salikhov IK. A deployable in vivo EPR tooth dosimeter for triage after a radiation event involving large populations. Radiat Meas 46:772-777; 2011. DOI:10.1016/j.radmeas.2011.03.009
43. Xu Y, Turner HC, Garty G, Brenner D. A rapid, quantitative method to characterize the human lymphocyte concentration for automated high-throughput radiation biodosimetry. Biomed Eng Res2:16-19; 2013
44. Yukihara EG, Mittani J, McKeever SWS, Simon SL. Optically stimulated luminescence (OSL) of dental enamel for retrospective assessment of radiation exposure. Radiat Meas 42:1256-1260; 2007. DOI:10.1016/j.radmeas.2007.05.038