In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes

Toxicology Letters

Volumn 228, Issue 1, 2014, Pages 48-55

  Crowell, S R ^a   Hanson Drury, S ^a   Williams, D E ^b   Corley, R A ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

Benzo a pyrene; Dibenzo def,p chrysene; Intrinsic clearance; Michaelis Menten

Indexed keywords

BENZO[A]PYRENE; CHRYSENE DERIVATIVE; DIBENZO[DEF,P]CHRYSENE; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HALF LIFE TIME; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIVER CLEARANCE; LIVER MICROSOME; LIVER MICROSOME METABOLISM; LIVER WEIGHT; MALE; MICHAELIS CONSTANT; MICHAELIS MENTEN KINETICS; MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; REACTION TIME; SEX DIFFERENCE;

BENZO[A]PYRENE; DIBENZO[DEF,P]CHRYSENE; INTRINSIC CLEARANCE; K(M); MICHAELIS-MENTEN; V(MAX);

ALGORITHMS; ANIMALS; BENZO(A)PYRENE; BENZOPYRENES; BODY WEIGHT; CARCINOGENS; DATA INTERPRETATION, STATISTICAL; FEMALE; HALF-LIFE; HUMANS; KINETICS; MALE; MICE; MICROSOMES, LIVER; ORGAN SIZE; POLYCYCLIC HYDROCARBONS, AROMATIC; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84899812022     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.04.004     Document Type: Article

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