Ketogenic diet alters dopaminergic activity in the mouse cortex

Neuroscience Letters

Volumn 571, Issue , 2014, Pages 1-4

  Church, William H ^a   Adams, Ryan E ^a   Wyss, Livia S ^a  

^a TRINITY COLLEGE   (United States)

Author keywords

Dopamine; HPLC; Ketogenic diet; Monoamines; Serotonin; Tissue punch

Indexed keywords

3,4 DIHYDROXYPHENYLACETIC ACID; 5 HYDROXYINDOLEACETIC ACID; DOPAMINE; HOMOVANILLIC ACID; MONOAMINE; NEUROTRANSMITTER; NORADRENALIN; SEROTONIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN REGION; CAUDATE NUCLEUS; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DOPAMINERGIC SYSTEM; ELECTROCHEMICAL ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KETOGENIC DIET; MESENCEPHALON; METABOLITE; MOTOR CORTEX; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PUTAMEN; SEIZURE; SOMATOSENSORY CORTEX; ULTRAVIOLET RADIATION; ANIMAL; METABOLISM;

3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; CEREBRAL CORTEX; DOPAMINE; HOMOVANILLIC ACID; KETOGENIC DIET; MESENCEPHALON; MICE; MOTOR CORTEX; NUCLEUS ACCUMBENS; PUTAMEN; SOMATOSENSORY CORTEX;

EID: 84899788975     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.04.016     Document Type: Article

References (25)

1. Hemingway C., Freeman J.M., Pillas D.J., Pyzik P.L. The ketogenic diet: a 3-to 6- year follow-up of 150 children enrolled prospectively. Pediatrics 2001, 108:898-905.
2. Sirven J., Whedon B., Caplan D., Liporace J., Glosser D., O'Dwyer J., Sperling M.R. The ketogenic diet for intractable epilepsy in adults: preliminary results. Epilepsia 1999, 40:1721-1726.
3. Dahlin M., Månsson J.E., Åmark P. CSF levels of dopamine and serotonin, but not norepinephrine, metabolites are influenced by the ketogenic diet in children with epilepsy. Epilepsy Res. 2012, 99:132-138.
4. Szot P., Weinshenker D., Rho J.M., Storey T.W., Schwartzkroin P.A. Norepinephrine is required for the anticonvulsant effect of the ketogenic diet. Dev. Brain Res. 2001, 129:211-214.
5. Weinshenker D. The contribution of norepinephrine and orexigenic neuropeptides to the anticonvulsant effect of the ketogenic diet. Epilepsia 2008, 49:104-107.
6. Green R.W. Adenosine: front and center in Linking nutrition and metabolism to neuronal activity. J. Clin. Invest. 2013, 10.1172/JCI58391.
7. 1 receptors. Clin. Invest. 2011, 121:2679-2683.
8. Masino S.A., Kawamura M., Ruskin D.N., Geiger J.D., Boison D. Purines and neuronal excitability: links to the ketogenic diet. Epilepsy Res. 2012, 100:229-238.
9. Dahlin M., Elfving Å., Ungerstedt U., Åmark P. The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy. Epilepsy Res. 2005, 64:115-125.
10. Yudkoff M., Daikhin Y., Nissim I., Lazarow A., Nissim I. Ketogenic diet, brain glutamate metabolism and seizure control. Prostaglandins Leukot. Essent. Fatty Acids 2004, 70:277-285.
11. Zarnowski T., Choragiewcz T., Tulidowicz-Bielak M., Thaler S., Rejdak R., Zarnowska I., Turski W.A., Gasior M. Ketogenic diet increases concentrations of kynurenic acid in descrete brain structures of young and adult rats. J. Neural. Transm. 2012, 119:679-684.
12. Cantello R., Varrasi C., Tarletti R., Cecchin M., D'Andrea F., Veggiotti P., Bellomo G., Monaco F. Ketogenic diet: electrophysiological effects on the normal human cortex. Epilepsia 2007, 48:1756-1763.
13. Church W.H., Sabol K.E., Justice J.B., Neill D.B. Striatal dopamine activity and unilateral barpressing in rats. Pharm. Biochem. Behav. 1986, 25:865-871.
14. Church W.H., Rappolt G. Nigrostriatal catecholamine metabolism is altered by purine enzyme inhibition. Exp. Brain Res. 1999, 127:147-150.
15. Franklin K.B.J., Paxinos G. The Mouse Brain in Stereotaxic Coordinates 1997, Academic Press, San Diego, California.
16. Ruskin D.N., Masino S.A. The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy. Front. Neurosci. 2012, 10.3389/fnins.2012.00033.
17. Yang X., Cheng B. Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity. J. Mol. Neurosci. 2010, 42:145-153.
18. Bozzi Y., Borrelli E. The role of dopamine signaling in epileptogenesis. Front. Cell. Neurosci. 2013, 7:1-12.
19. Mayne E.W., Craig M.T., McBain C.J., Paulsen O. Dopamine suppresses persistent network activity via D(1) -like dopamine receptors in rat medial entorhinal cortex. Eur. J. Neurosci. 2013, 37:1242-1247.
20. Awenowicz P.W., Porter L.L. Local application of dopamine inhibits pyramidal tract neuron activity in the rodent motor cortex. J. Neurophysiol. 2002, 88:3439-3451.
21. Ziemann U., Tergau F., Bruns D., Baudewig J., Paulus W. Changes in human motor cortex excitability induced by dopaminergic and anti-dopaminergic drugs. Electromyogr Motor Control 1997, 105:430-437.
22. Masino S.A., Geiger J.D. Are purines mediators of the anticonvulsive/neuroprotective effects of ketogenic diets. Trends Neurosci. 2008, 31:273-278.
23. Fiorillo C.D., Williams J.T. Selective inhibition by adenosine of mGluR IPSPs in dopamine neurons after cocaine treatment. J. Neurophysiol. 2000, 83:1307-1314.
24. Lund T.M., Risa Ø., Sonnewald U., Shousboe A., Waagepetersen H.S. Availability of neurotransmitter glutamate is diminished when β-hydroxybuterate replaces glucose in cultured neurons. J. Neurochem. 2009, 110:80-91.
25. Sharma N., Nehru B. Beneficial effect of vitamine E in rotenone induced model of PD: behavioral, neurochemical and biochemical study. Exp. Neurobiol. 2013, 22:214-223.