Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats

Journal of Trauma and Acute Care Surgery

Volumn 76, Issue 5, 2014, Pages 1169-1176

  Castellino, Francis J ^a   Chapman, Michael P ^d,e,f   Donahue, Deborah L ^a   Thomas, Scott ^b   Moore, Ernest E ^d,e   Wohlauer, Max V ^d,e   Fritz, Braxton ^c   Yount, Robert ^b   Ploplis, Victoria ^a   Davis, Patrick ^a,c   Evans, Edward ^b   Walsh, Mark ^a,b,c  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b is an assistant professor of nursing at Bethel College   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e DENVER HEALTH MEDICAL CENTER   (United States)

^f MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

ADP receptor; coagulopathy; platelet; thrombelastography; Traumatic brain injury

Indexed keywords

ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; KAOLIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD CLOTTING DISORDER; BRAIN HEMORRHAGE; BRAIN INJURY; COHORT ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; DIFFUSE AXONAL INJURY; FEMALE; GLASGOW COMA SCALE; GUNSHOT INJURY; HEAD INJURY; HEMORRHAGIC SHOCK; HUMAN; INJURY SEVERITY; INTERNATIONAL NORMALIZED RATIO; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PENETRATING TRAUMA; PRIORITY JOURNAL; PROTHROMBIN TIME; RAT; SUBDURAL HEMATOMA; THROMBOCYTE COUNT; THROMBOCYTE DYSFUNCTION; THROMBOCYTE FUNCTION; THROMBOELASTOGRAPHY; TRAUMATIC BRAIN INJURY;

ADULT; ANIMALS; ARACHIDONIC ACID; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION TESTS; BLOOD PLATELETS; BRAIN INJURIES; CASE-CONTROL STUDIES; DISEASE MODELS, ANIMAL; FEMALE; GLASGOW COMA SCALE; HUMANS; MALE; MIDDLE AGED; PLATELET ACTIVATION; PLATELET FUNCTION TESTS; PROSPECTIVE STUDIES; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; RISK ASSESSMENT; SHOCK, HEMORRHAGIC; STATISTICS, NONPARAMETRIC; THROMBELASTOGRAPHY;

EID: 84899787815     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000216     Document Type: Conference Paper

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