Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function

Journal of Experimental Medicine

Volumn 211, Issue 5, 2014, Pages 929-942

  Kumar, Lalit ^a,b   Chou, Janet ^a,b   Yee, Christina S K ^a,b   Borzutzky, Arturo ^a,b   Vollmann, Elisabeth H ^b   von Andrian, Ulrich H ^b   Park, Shin Young ^a,b   Hollander, Georg ^c,d   Manis, John P ^a,b   Luigi Poliani, P ^e   Geha, Raif S ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Department of Pediatrics Harvard Medical School ^*  (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAB2 PROTEIN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LEUCINE RICH REPEAT CONTAINING 8A; MEMBRANE PROTEIN; PROTEIN KINASE B; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; PROTEIN SERINE THREONINE KINASE; RAG2 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; B LYMPHOCYTE; BONE MARROW; CELL DIFFERENTIATION; CELL MATURATION; CELL SURVIVAL; CELL VIABILITY; CHIMERA; CONTROLLED STUDY; EPITHELIUM CELL; GROWTH RETARDATION; IN VITRO STUDY; LYMPHOCYTE FUNCTION; MORTALITY; MOUSE; NONHUMAN; PERINATAL PERIOD; PRENATAL PERIOD; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE DEVELOPMENT; THYMOCYTE; THYMUS;

ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; FLOW CYTOMETRY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; REAL-TIME POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; THYMOCYTES;

EID: 84899758699     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20131379     Document Type: Article

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