Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 5, 2014, Pages 995-1004

  Kraft, Bryan D ^a   Piantadosi, Claude A ^a   Benjamin, Ashlee M ^b   Lucas, Joseph E ^b   Zaas, Aimee K ^a,b   Betancourt Quiroz, Marisol ^a,b   Woods, Christopher W ^a,b   Chang, Alan L ^a   Roggli, Victor L ^a   Marshall, Craig D ^a   Ginsburg, Geoffrey S ^a,b   Welty Wolf, Karen ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY   (United States)

Author keywords

Biological markers; Cytokines; Gene expression; Sepsis; Streptococcus pneumoniae

Indexed keywords

ANTIBIOTIC AGENT; BIOLOGICAL MARKER; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; AUTOPSY; BABOON; BACTEREMIA; COLONY FORMING UNIT; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FEVER; GRAM STAINING; HISTOPATHOLOGY; HYPOXEMIA; INFLAMMATORY INFILTRATE; LABORATORY DIAGNOSIS; LEUKOCYTE COUNT; LEUKOCYTOSIS; LEUKOPENIA; LUNG EDEMA; LUNG INFILTRATE; LUNG LAVAGE; MACROPHAGE; MALE; MICROBIOLOGICAL EXAMINATION; NONHUMAN; ORGANIZING PNEUMONIA; PATHOPHYSIOLOGY; PHENOTYPE; PRIMATE MODEL; PROTEIN BLOOD LEVEL; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; TACHYCARDIA; TACHYPNEA; THORAX RADIOGRAPHY; VITAL SIGN;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE MODELS, ANIMAL; GRANULOCYTE COLONY-STIMULATING FACTOR; INTERLEUKINS; LUNG; PAPIO; PNEUMONIA, PNEUMOCOCCAL; PRIMATES; STREPTOCOCCUS PNEUMONIAE;

EID: 84899756111     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0340OC     Document Type: Article

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