RK-1355A and B, novel quinomycin derivatives isolated from a microbial metabolites fraction library based on NPPlot screening

Journal of Antibiotics

Volumn 67, Issue 4, 2014, Pages 323-329

  Lim, Chung Liang ^a,b   Nogawa, Toshihiko ^a   Uramoto, Masakazu ^a   Okano, Akiko ^a   Hongo, Yayoi ^a   Nakamura, Takemichi ^a   Koshino, Hiroyuki ^a   Takahashi, Shunji ^a   Ibrahim, Darah ^b   Osada, Hiroyuki ^a  

^a RIKEN   (Japan)

^b SCHOOL OF PHYSICS   (Malaysia)

Author keywords

antimicrobial activities; fraction library; microbial metabolites; quinomycin; spectral database; streptomyces sp.; structure elucidation

Indexed keywords

ANTIBIOTIC AGENT; RK 1355A; RK 1355B; UK 63598; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG DISCOVERY; ECHINOMYCIN; ESCHERICHIA COLI; HUMANS; INHIBITORY CONCENTRATION 50; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NEOPLASMS; SMALL MOLECULE LIBRARIES; STAPHYLOCOCCUS AUREUS; STREPTOMYCES;

EID: 84899744055     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.1038/ja.2013.144     Document Type: Article

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