Magnetic resonance imaging contrast of iron oxide nanoparticles developed for hyperthermia is dominated by iron content

International Journal of Hyperthermia

Volumn 30, Issue 3, 2014, Pages 192-200

  Wabler, Michele ^a   Zhu, Wenlian ^a   Hedayati, Mohammad ^a   Attaluri, Anilchandra ^a   Zhou, Haoming ^a   Mihalic, Jana ^b   Geyh, Alison ^b   Deweese, Theodore L ^a   Ivkov, Robert ^a   Artemov, Dmitri ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cancer; Magnetic iron oxide nanoparticles; Magnetic nanoparticle hyperthermia; Magnetic resonance imaging

Indexed keywords

BNF; CONTRAST MEDIUM; DEXTRAN; FERIDEX I.V; FERUCARBOTRAN; IRON OXIDE; MAGNETIC NANOPARTICLE; NANOMAG; POLY DEXTRO LYSINE; REAGENT; STARCH; SUPERPARAMAGNETIC IRON OXIDE; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; UNCLASSIFIED DRUG; FERRIC ION; FERRIC OXIDE; METAL NANOPARTICLE;

ARTICLE; CANCER CELL; CANCER THERAPY; CELL LEVEL; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DILUTION; DRUG DELIVERY SYSTEM; HUMAN; HUMAN CELL; HYPERTHERMIA; IMAGING; IRON TRANSPORT; MAGNETISM; MALE; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE IMAGING; PROSTATE CARCINOMA; HYPERTHERMIC THERAPY; PROCEDURES;

CONTRAST MEDIA; FERRIC COMPOUNDS; HYPERTHERMIA, INDUCED; MAGNETIC RESONANCE IMAGING; METAL NANOPARTICLES;

EID: 84899723473     PISSN: 02656736     EISSN: 14645157     Source Type: Journal    
DOI: 10.3109/02656736.2014.913321     Document Type: Article

References (58)

1. Pankhurst Q, Tranh N, Jones S, Dobson J. Progress in applications of magnetic nanoparticles in biomedicine. J Phys D: Appl Phys 2009;42:22401.
2. Jordan A, Wust P, Scholz R, Faehling H, Krause J, Felix R. Magnetic fluid hyperthermia (MFH). In: Hafeli U, Zborowski M, Schutt W, Teller J, editors. Scientific and Clinical Applications of Magnetic Carriers. New York: Plenum Press; 1997. pp 569-95.
3. Corot C, Robert P, Idée JM, Port M. Recent advances in iron oxide nanocrystal technology for medical imaging. Adv Drug Delivery Rev 2006;58:1471-504.
4. Neuberger T, Schöpf B, Hofmann H, Hofmann M, von Rechenberg B. Superparamagnetic nanoparticles for biomedical applications: Possibilities and limitations of a new drug delivery system. J Magn Magn Mater 2005;293:483-96.
5. Sun C, Lee JSH, Zhang M. Magnetic nanoparticles in MR imaging and drug delivery. Adv Drug Del Rev 2008;60:1252-65.
6. Bordelon D, Cornejo C, Grüttner C, Westphal F, DeWeese TL, Ivkov R. Magnetic nanoparticle heating efficiency reveals magneto-structural differences when characterized with wide ranging and high amplitude alternating magnetic fields. J Appl Phys 2011; 109:124904.
7. Dennis CL, Ivkov R. Physics of heat generation using magnetic nanoparticles for hyperthermia. Int J Hyperthermia 2013;29: 715-29.
8. Gilchrist RK, Medal R, Shorey WD, Hanselman RC, Parrott JC, Taylor CB. Selective inductive heating of lymph nodes. Ann Surg 1957;146:596-606.
9. Hergt R, Dutz S. Magnetic particle hyperthermia-Biophysical limitations of a visionary tumor therapy. J Magn Magn Mater 2007; 311:187-92.
10. Carrey J, Mehdaoui B, Respaud M. Simple models for dynamic hysteresis loop calculations of magnetic single-domain nanoparticles: Application to magnetic hyperthermia optimization. J Appl Phys 2011;109:083921.
11. Dutz S, Kettering M, Hilger I, Müller R, Zeisberger M. Magnetic multicore nanoparticles for hyperthermia-Influence of particle immobilization in tumour tissue on magnetic properties. Nanotechnology 2011;22:265102.
12. Stauffer PR, Sneed PK, Hashemi H, and Phillips TL. Practical induction heating coil designs for clinical hyperthermia with ferromagnetic implants. IEEE Trans Biomed Eng 1994;41:17-28.
13. DeNardo SJ, DeNardo GL, Natarajan A, Miers LA, Foreman AR, Gruettner C, et al. Thermal dosimetry predictive of efficacy of 111In-ChL6 nanoparticle AMF-induced thermoablative therapy for human breast cancer in mice. J Nuc Med 2007;48:437-44.
14. Wust P, Gneveckow U, Johannsen M, Böhmer D, Henkel T, Kahmann F, et al. Magnetic nanoparticles for interstitial thermotherapy-Feasibility, tolerance and achieved temperatures. Int J Hyperthermia 2006;22:673-85.
15. Johannsen M, Gneveckow U, Eckelt L, Feussner A, Waldofner N, Scholz R, et al. Clinical hyperthermia of prostate cancer using magnetic nanoparticles: Presentation of a new interstitial technique. Int J Hyperthermia 2005;21:637-47.
16. Jordan A, Maier-Hauff K. Magnetic nanoparticles for intracranial thermotherapy. J Nanosci Nanotechnol 2007;7:4604-6.
17. Lin JC, Bernardi P. Computational methods for predicting field intensity and temperature change. In: Barnes FS, Greenebaum B, editors. Bioengineering and Biophysical Aspects of Electromagnetic Fields, 3rd ed. Boca Raton: CRC Press; 2007. pp 293-380.
18. Liu F, Zhao H, Crozier S. On the induced electric field gradients in the human body for magnetic stimulation by gradient coils in MRI. IEEE Trans Biomed Eng 2003;50:804-15.
19. Adair ER, Black DR. Thermoregulatory responses to RF energy absorption. Bioelectromagnetics 2003;6:S17-38.
20. Trakic A, Liu F, Crozier S. Transient temperature rise in a mouse due to low-frequency regional hyperthermia. Phys Med Biol 2006; 51:1673-91.
21. Ivkov R, DeNardo SJ, Daum W, Foreman AR, Goldstein RC, Nemkov VS, et al. Application of high amplitude alternating magnetic fields for heat induction of nanoparticles localized in cancer. Clin Cancer Res 2005;11:S7093-103.
22. Atkinson WJ, Brezovich IA, Chakraborty DP. Usable frequencies in hyperthermia with thermal seeds. IEEE Trans Biomed Eng 1984; 31:70-5.
23. Artemov D. Molecular magnetic resonance imaging with targeted contrast agents. J Cell Biochem 2003;90:518-24.
24. Artemov D. MRI for molecular imaging applications: Overview, perspectives, and challenges. In: Willard HF, Ginsburg GS, editors. Genomic and Personalized Medicine, vol. 1. San Diego, CA: Elsevier Academic Press; 2009. pp 512-23.
25. Liu W, Frank JA. Detection and quantification of magnetically labeled cells by cellular MRI. Eur J Radiol 2009;70:258-64.
26. Laurent S, Forge D, Port M, Roch A, Robic C, Elst LV, et al. Magnetic iron oxide nanoparticles: Synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications. Chem Rev 2008;108:2064-110.
27. Ivkov R. Magnetic nanoscale particle compositions, and therapeutic methods related thereto. US Patent 7,731,648.
28. Grüttner C, Müller K, Teller J, Westphal F, Foreman A., Ivkov R. Synthesis and antibody conjugation of magnetic nanoparticles with improved specific power absorption rates for alternating magnetic field cancer therapy. J Magn Magn Mater 2007;311:181-6.
29. Hedayati M, Attaluri A, Bordelon D, Goh R, Armour M, Zhou H, et al. New iron-oxide particles for magnetic nanoparticle hyperthermia: An in-vitro and in-vivo pilot study. Proc SPIE 2013, 8584, 858404-1-10.
30. Dennis CL, Jackson AJ, Borchers JA, Ivkov R, Foreman AR, Lau JW, et al. The influence of collective behavior on the magnetic and heating properties of iron oxide nanoparticles. J Appl Phys 2008; 103:07A319.
31. Dennis CL, Jackson AJ, Borchers JA, Hoopes PJ, Strawbridge R, Foreman AR, et al. Nearly complete regression of tumors via collective behavior of magnetic nanoparticles in hyperthermia. Nanotechnology 2009;20:395103.
32. Lartigue L, Hugounenq P, Alloyeau D, Clarke SP, Levy M, Bacri JC, et al. Cooperative organization in iron oxide multi-core nanoparticles potentiates their efficiency as heating mediators and MRI contrast agents. ACS Nano 2012;6:10935-49.
33. Girard OM, Du J, Agemy L, Sugahara KN, Kotamraju VR, Ruoslahti E, et al. Optimization of iron oxide nanoparticle detection using ultrashort echo time pulse sequences: Comparison of T1, T-2 , and synergistic T1-T-2 contrast mechanisms. Magn Reson Med 2011;65:1649-60.
34. Liu W, Dahnke H, Jordan EK, Schaeffter T, Frank JA. In vivo MRI using positive-contrast techniques in detection of cells labeled with superparamagnetic iron oxide nanoparticles. NMR Biomed 2008; 21:242-50.
35. Girard OM, Ramirez R, McCarty S, Mattrey RF. Toward absolute quantification of iron oxide nanoparticles as well as cell internalized fraction using multiparametric MRI. Contrast Media Mol Imaging 2012;7:411-17.
36. Billotey C, Wilhelm C, Devaud M, Bacri JC, Bittoun J, Gazeau F. Cell internalization of anionic maghemite nanoparticles: Quantitative effect on magnetic resonance imaging. Magn Reson Med 2003;49:646-54.
37. Bowen CV, Zhange XW, Saab G, Gareau PJ, Rutt BK. Application of the static dephasing regime theory to superparamagnetic ironoxide loaded cells. Magn Reson Med 2002;48:52-61.
38. Yablonskiy DA, Haacke EM. Theory of NMR signal behavior in magnetically inhomogeneous tissues: The static dephasing regime. Magn Reson Med 1994;32:749-63.
39. Wang Y-XJ, Hussain SM, Krestin GP. Superparamagnetic iron oxide contrast agents: Physicochemical characteristics and applications in MR imaging. Eur Radiol 2001;11:2319-31.
40. Feridex-prescribing information. Bayer Healthcare Pharmaceuticals, 2007. Available at: Http://www.rxlist.com/feridex-iv-drug/overdosage- contraindications.htm.
41. Reimer P, Balzer T. Ferucarbotran (Resovist): A new clinically approved RES-specific contrast agent for contrast-enhanced MRI of the liver: Properties, clinical development, and applications. Eur Radiol 2003;13:1266-76.
42. Gupta AK, Gupta M. Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications. Biomaterials 2005; 26:3995-4021.
43. Schlorf T, Meincke M, Kossel E, Glüer CC, Jansen O, Mentlein R. Biological properties of iron oxide nanoparticles for cellular and molecular magnetic resonance imaging. Int J Mol Sci 2011;12: 12-23.
44. Raynal I, Prigent P, Peyramaure S, Najid A, Rebuzzi C, Coro C. Macrophage endocytosis of superparamagnetic iron oxide nanoparticles: Mechanisms and comparison of ferumoxides and ferumoxtran-10. Invest Radiol 2004;39:56-63.
45. Lee N, Choi Y, Lee Y, Park M, Moon WK, Choi SH, et al. Waterdispersible ferromagnetic iron oxide nanocubes with extremely high r2 relaxivity for highly sensitive in vivo MRI of tumors. Nano Lett 2012;12:3127-31.
46. Grüttner C, Müller K, Teller J, Westphal F, Foreman A., Ivkov R. Synthesis and antibody conjugation of magnetic nanoparticles with improved specific power absorption rates for alternating magnetic field cancer therapy. J Magn Magn Mater 2007;311: 181-6.
47. Grüttner C, Teller J, Schütt W, Westphal F, Schümichen C, Paulke BR. Preparation and characterization of magnetic nanospheres for in vivo application. In: Hafeli U, Zborowski M, Schutt W, Teller J, editors. Scientific and Clinical Applications of Magnetic Carriers. New York: Plenum Press; 1997. pp 53-68.
48. Rudershausen S, Grüttner C, Frank M, Teller J, Westphal F. Multifunctional superparamagnetic nanoparticles for life science applications. Eur Cells Mater 2002;3:81-3.
49. Hedayati M, Thomas O, Abubaker-Sharif B, Zhou H, Cornejo C, Zhang Y, et al. The effect of cell cluster size on intracellular nanoparticle-mediated hyperthermia: Is it possible to treat microscopic tumors? Nanomedicine (Lond) 2013;8:29-41.
50. Frank JA, Zywicke H, Jordan EK, Mithcel J, Lewis BK, Miller B, et al. Magnetic intracellular labeling of mammalian cells by combining (FDA-Approved) superparamagnetic iron oxide MR contrast agents and commonly used transfection agents. Acad Radiol 2002;9:S484-7.
51. Richards JMJ, Shaw CA, Lang NN, Williams MC, Semple SIK, MacGillivray TJ, et al. In vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: Feasibility and safety in humans. Circ Cardiovasc Imaging 2012;5:509-17.
52. Karussis D, Karageorgiou C, Vaknin-Dembinsky A, Gowda-Kurkalli B, Gomori JM, Kassis I. Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis. Arch Neurol 2010;67: 1187-94.
53. Shapiro EM, Skrtic S, Sharer K, Hill JM, Dunbar CE, Koretsky AP. MRI detection of single particles for cellular imaging. Proc Natl Acad Sci 2004;101:10901-6.
54. Lee H, Yoon T-J, Figueiredo J-L, Swirski FK, Weissleder R. Rapid detection and profiling of cancer cells in fine-needle aspirates. PNAS 2009;106:12459-64.
55. Branquinho LC, Carriao MS, Costa AS, Zufelato N, Sousa MH, Miotto R, et al. Effect of magnetic dipolar interactions on nanoparticle heating efficiency: Implications for cancer hyperthermia. Sci Rep 2013;3:2887.
56. Gossuin Y, Gillis P, Bue FL. Susceptibility-induced T2-shortening and unrestricted diffusion. Magn Res Med 2002;47:194-5.
57. Gillis P, Moiny F, Brooks RA. On T2-shortening by strongly magnetized spheres: A partial refocusing model. Magn Res Med 2002;47:257-63.
58. Pöselt E, Kloust H, Tromsdorf U, Janschel M, Han C, Mablo C, et al. Relaxivity optimization of a PEGylated iron-oxide-based negative magnetic resonance agent for T2-weighted spin-echo imaging. ACS Nano 2012;2:1619-24.