메뉴 건너뛰기




Volumn 99, Issue 5, 2014, Pages

Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia

Author keywords

Chronic lymphocytic leukemia; Lenalidomide; T cell imhibitory receptors

Indexed keywords

CD57 ANTIGEN; FLUDARABINE; LENALIDOMIDE; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR 2B4; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN RECEPTOR; THALIDOMIDE;

EID: 84899722959     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.098459     Document Type: Letter
Times cited : (33)

References (15)
  • 1
    • 70349562920 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of CLL: Novel therapeutic approaches
    • Pleyer L, Egle A, Hartmann TN, Greil R. Molecular and cellular mechanisms of CLL: novel therapeutic approaches. Nat Rev Clin Oncol. 2009; 6(7): 405-18.
    • (2009) Nat Rev Clin Oncol , vol.6 , Issue.7 , pp. 405-418
    • Pleyer, L.1    Egle, A.2    Hartmann, T.N.3    Greil, R.4
  • 2
    • 51749087317 scopus 로고    scopus 로고
    • The immunodeficiency of chronic lymphocytic leukaemia
    • Hamblin AD, Hamblin TJ. The immunodeficiency of chronic lymphocytic leukaemia. Br Med Bull. 2008; 87: 49-62.
    • (2008) Br Med Bull , vol.87 , pp. 49-62
    • Hamblin, A.D.1    Hamblin, T.J.2
  • 3
    • 84865165316 scopus 로고    scopus 로고
    • Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: Establishing a reversible immune evasion mechanism in human cancer
    • Ramsay AG, Clear AJ, Fatah R, Gribben JG. Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer. Blood. 2012; 120(7): 1412-21.
    • (2012) Blood , vol.120 , Issue.7 , pp. 1412-1421
    • Ramsay, A.G.1    Clear, A.J.2    Fatah, R.3    Gribben, J.G.4
  • 4
    • 84856515333 scopus 로고    scopus 로고
    • Expansion of a CD8+PD-1+ replicative senescence phenotype in early stage CLL patients is associated with inverted CD4: CD8 ratios and disease progression
    • Nunes CT, Wong R, Mason M, Fegan C, Man S, Pepper C. Expansion of a CD8+PD-1+ replicative senescence phenotype in early stage CLL patients is associated with inverted CD4: CD8 ratios and disease progression. Clin Cancer Res. 2012; 18(3): 678-87.
    • (2012) Clin Cancer Res , vol.18 , Issue.3 , pp. 678-687
    • Nunes, C.T.1    Wong, R.2    Mason, M.3    Fegan, C.4    Man, S.5    Pepper, C.6
  • 5
    • 84878458037 scopus 로고    scopus 로고
    • The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia
    • Brusa D, Serra S, Coscia M, Rossi D, D'Arena G, Laurenti L, et al. The PD-1/PD-L1 axis contributes to T-cell dysfunction in chronic lymphocytic leukemia. Haematologica. 2013; 98(6): 953-63.
    • (2013) Haematologica , vol.98 , Issue.6 , pp. 953-963
    • Brusa, D.1    Serra, S.2    Coscia, M.3    Rossi, D.4    D'Arena, G.5    Laurenti, L.6
  • 6
    • 46749132717 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug
    • Ramsay AG, Johnson AJ, Lee AM, Gorgun G, Le Dieu R, Blum W, et al. Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug. J Clin Invest. 2008; 118(7): 2427-37.
    • (2008) J Clin Invest , vol.118 , Issue.7 , pp. 2427-2437
    • Ramsay, A.G.1    Johnson, A.J.2    Lee, A.M.3    Gorgun, G.4    Le Dieu, R.5    Blum, W.6
  • 7
    • 84857059757 scopus 로고    scopus 로고
    • Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells
    • Youngblood B, Wherry EJ, Ahmed R. Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells. Curr Opin HIV AIDS. 2012; 7(1): 50-7.
    • (2012) Curr Opin HIV AIDS , vol.7 , Issue.1 , pp. 50-57
    • Youngblood, B.1    Wherry, E.J.2    Ahmed, R.3
  • 8
    • 79961208153 scopus 로고    scopus 로고
    • CD8(+) CD28(-) and CD8(+) CD57(+) T cells and their role in health and disease
    • Strioga M, Pasukoniene V, Characiejus D. CD8(+) CD28(-) and CD8(+) CD57(+) T cells and their role in health and disease. Immunology. 2011; 134(1): 17-32.
    • (2011) Immunology , vol.134 , Issue.1 , pp. 17-32
    • Strioga, M.1    Pasukoniene, V.2    Characiejus, D.3
  • 9
    • 29144470075 scopus 로고    scopus 로고
    • Functional and phenotypic characterization of CD57(+)CD4(+) T cells and their association with HIV-1-induced T cell dysfunction
    • Palmer BE, Blyveis N, Fontenot AP, Wilson CC. Functional and phenotypic characterization of CD57(+)CD4(+) T cells and their association with HIV-1-induced T cell dysfunction. J Immunol. 2005; 175(12): 8415-23.
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 8415-8423
    • Palmer, B.E.1    Blyveis, N.2    Fontenot, A.P.3    Wilson, C.C.4
  • 10
    • 77954674575 scopus 로고    scopus 로고
    • Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCVSpecific CD8+T Cells Is Linked to Antigen Recognition and T Cell Differentiation
    • Bengsch B, Seigel B, Ruhl M, Timm J, Kuntz M, Blum HE, et al. Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCVSpecific CD8+T Cells Is Linked to Antigen Recognition and T Cell Differentiation. PLoS Pathog. 2010; 6(6): e1000947.
    • (2010) PLoS Pathog , vol.6 , Issue.6
    • Bengsch, B.1    Seigel, B.2    Ruhl, M.3    Timm, J.4    Kuntz, M.5    Blum, H.E.6
  • 11
    • 84874109734 scopus 로고    scopus 로고
    • A Combination of Fludarabine/Rituximab with Escalating Doses of Lenalidomide in Previously Untreated Chronic Lymphocytic Leukemia (CLL): The REVLIRIT CLL5 AGMT Phase I/II Study, Clinical and Exploratory Analyses of Induction Results
    • Egle A, Steurer M, Gassner F, Geisberger R, Melchardt T, Weiss L, et al. A Combination of Fludarabine/Rituximab with Escalating Doses of Lenalidomide in Previously Untreated Chronic Lymphocytic Leukemia (CLL): The REVLIRIT CLL5 AGMT Phase I/II Study, Clinical and Exploratory Analyses of Induction Results. Blood. 2011; 118(21): 135-6.
    • (2011) Blood , vol.118 , Issue.21 , pp. 135-136
    • Egle, A.1    Steurer, M.2    Gassner, F.3    Geisberger, R.4    Melchardt, T.5    Weiss, L.6
  • 12
    • 59249090000 scopus 로고    scopus 로고
    • Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals
    • Chidrawar S, Khan N, Wei W, McLarnon A, Smith N, Nayak L, et al. Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals. Clin Exp Immunol. 2009; 155(3): 423-32.
    • (2009) Clin Exp Immunol , vol.155 , Issue.3 , pp. 423-432
    • Chidrawar, S.1    Khan, N.2    Wei, W.3    McLarnon, A.4    Smith, N.5    Nayak, L.6
  • 13
    • 79953755051 scopus 로고    scopus 로고
    • Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia
    • Gassner FJ, Weiss L, Geisberger R, Hofbauer JP, Egle A, Hartmann TN, et al. Fludarabine modulates composition and function of the T cell pool in patients with chronic lymphocytic leukaemia. Cancer Immunol Immunother. 2011; 60(1): 75-85.
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.1 , pp. 75-85
    • Gassner, F.J.1    Weiss, L.2    Geisberger, R.3    Hofbauer, J.P.4    Egle, A.5    Hartmann, T.N.6
  • 14
    • 84880276168 scopus 로고    scopus 로고
    • Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL)
    • Shanafelt TD, Ramsay AG, Zent CS, Leis JF, Tun HW, Call TG, et al. Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL). Blood. 2013; 121(20): 4137-41.
    • (2013) Blood , vol.121 , Issue.20 , pp. 4137-4141
    • Shanafelt, T.D.1    Ramsay, A.G.2    Zent, C.S.3    Leis, J.F.4    Tun, H.W.5    Call, T.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.