Effect of gender differences on the regulation of renal ischemia-reperfusion-induced inflammation in mice

Molecular Medicine Reports

Volumn 9, Issue 6, 2014, Pages 2061-2068

  Kang, Kyung Pyo ^a   Lee, Jung Eun ^a   Lee, Ae Sin ^a   Jung, Yu Jin ^a   Kim, Dal ^a   Lee, Sik ^a   Hwang, Hong Pil ^a   Kim, Won ^a   Park, Sung Kwang ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Acute kidney injury; Disparity; Gender; Inflammation

Indexed keywords

COMPLEMENTARY DNA; CYTOKINE; ESTRADIOL; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA; TESTOSTERONE PROPIONATE; TUMOR NECROSIS FACTOR ALPHA; INTERCELLULAR ADHESION MOLECULE 1; SEX HORMONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASTRATION; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HISTOLOGY; IMMUNE SYSTEM; INFLAMMATION; KIDNEY FUNCTION; KIDNEY ISCHEMIA; MACROPHAGE; MALE; MOUSE; NONHUMAN; OVARIECTOMY; POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SEX DIFFERENCE; WESTERN BLOTTING; ACUTE KIDNEY INJURY; ANIMAL; COMPLICATION; DISEASE MODEL; GENE EXPRESSION; GENETICS; IMMUNOLOGY; KIDNEY FUNCTION TEST; KIDNEY TUBULE; METABOLISM; NEPHRITIS; PATHOLOGY; PATHOPHYSIOLOGY;

ACUTE KIDNEY INJURY; ANIMALS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; GONADAL STEROID HORMONES; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY FUNCTION TESTS; KIDNEY TUBULES; MACROPHAGES; MALE; MICE; NEPHRITIS; REPERFUSION INJURY; SEX FACTORS;

EID: 84899689802     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2089     Document Type: Article

References (16)

1. Ferenbach D, Kluth DC and Hughes J: Inflammatory cells in renal injury and repair. Semin Nephrol 27: 250 -259, 2007.
2. Akcay A, Nguyen Q and Edelstein CL: Mediators of inflammation in acute kidney injury. Mediators Inflamm 2009: 137072, 2009.
3. Kher A, Meldrum KK, Wang M, Tsai BM, Pitcher JM and Meldrum DR: Cellular and molecular mechanisms of sex differences in renal ischemia-reperfusion injury. Cardiovasc Res 67: 594-603, 2005. (Pubitemid 41033355)
4. Neugarten J, Acharya A and Silbiger SR: Effect of gender on the progression of nondiabetic renal disease: a meta-analysis. J Am Soc Nephrol 11: 319-329, 2000. (Pubitemid 30064855)
5. Park KM, Kim JI, Ahn Y, Bonventre AJ and Bonventre JV: Testosterone is responsible for enhanced susceptibility of males to ischemic renal injury. J Biol Chem 279: 52282-52292, 2004. (Pubitemid 39656602)
6. Kim J, Kil IS, Seok YM, et al: Orchiectomy attenuates post-ischemic oxidative stress and ischemia/reperfusion injury in mice. A role for manganese superoxide dismutase. J Biol Chem 281: 20349-20356, 2006. (Pubitemid 44065809)
7. Takaoka M, Yuba M, Fujii T, Ohkita M and Matsumura Y: Oestrogen protects against ischaemic acute renal failure in rats by suppressing renal endothelin-1 overproduction. Clin Sci (Lond) 103 (Suppl 48): 434S-437S, 2002. (Pubitemid 35007205)
8. Satake A, Takaoka M, Nishikawa M, et al: Protective effect of 17beta-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway. Kidney Int 73: 308-317, 2008.
9. Jung YJ, Kim DH, Lee AS, et al : Peritubular capillary preservation with COMP-angiopoietin-1 decreases ischemia-reperfusion-induced acute kidney injury. Am J Physiol Renal Physiol 297: F952-F960, 2009.
10. Kang KP, Kim DH, Jung YJ, et al: Alpha-lipoic acid attenuates cisplatin-induced acute kidney injury in mice by suppressing renal inflammation. Nephrol Dial Transplant 24: 3012-3020, 2009.
11. Lee AS, Lee JE, Jung YJ, et al: Vascular endothelial growth factor-C and -D are involved in lymphangiogenesis in mouse unilateral ureteral obstruction. Kidney Int 83: 50-62, 2013.
12. Kang KP, Park SK, Kim DH, et al: Luteolin ameliorates cisplatin-induced acute kidney injury in mice by regulation of p53-dependent renal tubular apoptosis. Nephrol Dial Transplant 26: 814-822, 2011.
13. Chung AC and Lan HY: Chemokines in renal injury. J Am Soc Nephrol 22: 802-809, 2011.
14. Shen SQ, Zhang Y and Xiong CL: The protective effects of 17beta-estradiol on hepatic ischemia-reperfusion injury in rat model, associated with regulation of heat-shock protein expression. J Surg Res 140: 67-76, 2007. (Pubitemid 46669544)
15. Yong Y, Xie HJ, Zhang YF, et al: 17beta-estradiol potentiates ischemia-reperfusion injury in diabetic ovariectomized female rats. Brain Res 1054: 192-199, 2005. (Pubitemid 41219349)
16. Squadrito F, Altavilla D, Squadrito G, et al: 17Beta-oestradiol reduces cardiac leukocyte accumulation in myocardial ischaemia reperfusion injury in rat. Eur J Pharmacol 335: 185-192, 1997. (Pubitemid 27450484)