Association of blood lead level with neurological features in 972 children affected by an acute severe lead poisoning outbreak in zamfara state, Northern Nigeria

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Greig, Jane ^a   Thurtle, Natalie ^a   Cooney, Lauren ^a   Ariti, Cono ^b   Ahmed, Abdulkadir Ola ^a   Ashagre, Teshome ^a   Ayela, Anthony ^a   Chukwumalu, Kingsley ^a   Criado Perez, Alison ^a   Gómez Restrepo, Camilo ^a   Meredith, Caitlin ^a   Neri, Antonio ^c   Stellmach, Darryl ^a,d   Sani Gwarzo, Nasir ^e   Nasidi, Abdulsalami ^f   Shanks, Leslie ^a   Dargan, Paul I ^a,g  

^a MÉDECINS SANS FRONTIÈRES   (Switzerland)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e Federal Ministry of Health   (Nigeria)

^f NIGERIA CENTRE FOR DISEASE CONTROL   (Nigeria)

^g GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD;

AGE; ARTICLE; BRAIN DISEASE; CHELATION; CHILD; EPIDEMIC; FEMALE; HUMAN; INFANT; LEAD BLOOD LEVEL; LEAD POISONING; MALARIA; MALE; NEWBORN; NIGERIA; PRESCHOOL CHILD; RETROSPECTIVE STUDY; RISK FACTOR; SEIZURE; BLOOD; COMPLICATION; NEUROTOXICITY SYNDROMES; STATISTICAL MODEL;

CHILD, PRESCHOOL; HUMANS; INFANT; LEAD; LEAD POISONING; LOGISTIC MODELS; MALARIA; NEUROTOXICITY SYNDROMES; NIGERIA; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84899685460     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093716     Document Type: Article

References (49)

1. Waldron T (1978) Did Hippocrates describe lead poisoning? Lancet 2: 1315.
2. Nriagu J (1983) Saturnine gout among Roman aristocrats. Did lead poisoning contribute to the fall of the Empire? N Engl J Med 308: 660-663.
3. Scarborough J (1984) The myth of lead poisoning among the Romans: an essay review. J Hist Med Allied Sci 39: 469-475.
4. World Health Organisation (2010) Childhood lead poisoning (2010) Available: http://www.who.int/ceh/publications/leadguidance.pdf. Accessed 2012 October 3.
5. Gerr F, Letz R, Stokes L, Chettle D, McNeill F, et al. (2002) Association between bone lead concentration and blood pressure among young adults. Am J Ind Med 42: 98-106.
6. Payton M, Hu H, Sparrow D, Weiss ST (1994) Low-level lead exposure and renal function in the Normative Aging Study. Am J Epidemiol 140: 821-829.
7. Gennart JP, Buchet JP, Roels H, Ghyselen P, Ceulemans E, et al. (1992) Fertility of male workers exposed to cadmium, lead, or manganese. Am J Epidemiol 135: 1208-1219.
8. Mielke HW, Zahran S (2012) The urban rise and fall of air lead (Pb) and the latent surge and retreat of societal violence. Environ Int 43: 48-55. Epub 2012 Apr 6. doi:10.1016/j.envint.2012.03.005
9. Lanphear BP, Dietrich K, Auinger P, Cox C (2000) Cognitive deficits associated with blood lead concentrations ,10 microg/dL in US children and adolescents. Public Health Rep 115: 521-529.
10. National Academy of Sciences (1972) Unpublished data from the patient populations reported in Chisolm (1962, 1965) and Chisolm and Harrison (1956).
11. Coffin R, Phillips JL, Staples WI, Spector S (1996) Treatment of lead encephalopathy in children. J Pediatr. 69(2): 198-206.
12. Chisolm JJ, Harrison HE (1956) The Exposure of Children to Lead. Pediatrics18: 943-958.
13. McDonald JM, Kaplan E (1942) Incidence of lead poisoning in the city of Baltimore. JAMA 119:870-872.
14. Chisolm JJ Jr, Harrison HE (1957) Treatment of Acute Lead Encephalopathy in Children. Pedatrics 19: 2.
15. Greengard J, Adams B, Berman E (1965) Acute lead encephalopathy in young children. J Ped 66: 707-711.
16. Berg KK, Hull HF, Zabel EW, Staley PK, Brown MJ (2006) Death of a Child After Ingestion of a Metallic Charm -Minnesota. MMWR Dispatch 55: 1-2.
17. CDC (2001) Fatal Pediatric Lead Poisoning-New Hampshire, 2000. MMWR. 50:457-459.
18. Haefliger P, Mathieu-Nolf M, Lociciro S, Ndiaye C, Coly M, et al. (2009) Mass lead intoxication from informal used lead-acid battery recycling in Dakar, Senegal. Environ Health Perspect 117:1535-40.
19. Biya O, Gidado S, Haladu S, Geoffrey T, Nguku P, et al. (2010) Notes from the Field: Outbreak of Acute Lead Poisoning Among Children Aged ,5 Years - Zamfara, Nigeria, 2010. MMWR 59: 846.
20. Dooyema CA, Neri A, Lo Y, Durant J, Dargan PI, et al. (2011) Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010. Environ Health Perspect 120: 601-607.
21. Centers for Disease Control (2002). Managing Elevated Blood Lead Levels Among Young Children: Recommendations from the Advisory Committee on Childhood Lead Poisoning Prevention. Available: http://www.cdc.gov/nceh/ lead/CaseManagement/caseManage-main.htm. Accessed 2012 October 3.
22. Plumlee GS, Durant JT, Morman SA, Neri A, Wolf RE, et al. (2013) Linking geological and health sciences to assess childhood lead poisoning from artisanal gold mining in Nigeria. Environ Health Perspect 121:744-50.
23. Lo YC, Dooyema CA, Neri A, Durant J, Jefferies T, et al. (2012) Childhood lead poisoning associated with gold ore processing: a village-level investigationzamfara state, Nigeria, October-November 2010. Environ Health Perspect 120: 1450-1455.
24. Rogan WJ, Dietrich KN, Ware JH, Dockery DW, Salganik M, et al. (2001) Treatment of Lead-Exposed Children Trial Group; The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead. N Engl J Med 344: 1421-1426.
25. Rummo JH, Routh DK, Rummo NJ, Brown JF (1979) Behavioral and neurological effects of symptomatic and asymptomatic lead exposure in children. Arch Environ Health 34: 120-124.
26. Agency for Toxic Substances and Disease Registry; Toxicological Profile for Lead; 2007 Available: http://www.atsdr.cdc.gov/toxprofiles/tp13.pdf. Accessed 2013 Aug 8.
27. Betts PR, Astley R, Raine DN (1973) Lead intoxication in children in Birmingham. BMJ 1:402-406.
28. Greengard J, Adams B, Berman E (1965) Acute lead encephalopathy in young children. J Pediatr 66: 707-711.
29. Kelly CA, Upex A, Bateman DN (2004) Comparison of consciousness level assessment in the poisoned patient using the alert/verbal/painful/unresponsive scale and the Glasgow Coma Scale. Ann Emerg Med 44: 108-113.
30. Neri A, Roy J, Jarrett J, Pan Y, Dooyema C, et al. (2013) Analysis of a Novel Field Dilution Method for Testing Samples that Exceed the Analytic Range of Point-of-Care Blood Lead Analyzers. Int J Environ Health Res. Online Nov. 25, 2013.
31. Bland JM, Altman DG (2010) Statistical methods for assessing agreement between two methods of clinical measurement. Int J Nursing Studies 47: 931-936.
32. National Population Commission (NPC) [Nigeria], National Malaria Control Programme (NMCP) [Nigeria], and ICF International. 2012. Nigeria Malaria Indicator Survey 2010. Abuja, Nigeria: NPC, NMCP, and ICF International. Available: http://measuredhs.com/pubs/pdf/MIS8/MIS8.pdf. Accessed 2014 February 4.
33. Cheesbrough M (2006) District Laboratory Practice in Tropical Countries. Cambridge: Cambridge University Press.
34. USA EPA (2005) Guidance on Selecting Age Groups for Monitoring and Assessing Childhood Exposures to Environmental Contaminants. Available: http://www.epa.gov/raf/publications/pdfs/AGEGROUPS.PDF. Accessed 2012 October 3.
35. MSF Ethics Review Board (2013) Standard Operating Procedures. Geneva: MSF. Available: http://fieldresearch.msf.org/msf/handle/10144/294968. Accessed 2013 July 21.
36. Treatment of Lead-Exposed Children (TLC) Trial Group (2000) Safety and efficacy of succimer in toddlers with blood lead levels of 20-44 microg/dL. Pediatr Res. 48:593-9.
37. Selevan SG, Rice DC, Hogan KA, Euling SY, Pfahles-Hutchens A, et al. (2003) Blood lead concentration and delayed puberty in girls. N Engl J Med 348: 1527-1536.
38. Den Hond E, Nawrot T, Staessen JA (2002) The relationship between blood pressure and blood lead in NHANES III. National Health and Nutritional Examination Survey. J Hum Hypertens 16: 563-568.
39. Watts J (2009) Lead poisoning cases spark riots in China. Lancet 374:868. Correction: Department of Error 374: 1596
40. Parry J (2009) Hundreds of Chinese children are left poisoned as metal smelting plants are ordered to close. BMJ 339:b3433
41. Zhao TT, Chen B, Wang HP, Wang R, Zhang H (2013) Evaluation of toxic and essential elements in whole blood from 0-to 6-year-old children from Jinan, China. Clin Biochem 46:612-616.
42. He K, Wang S, Zhang J (2009) Blood lead levels of children and its trend in China. Sci Total Environ 407:3986-93.
43. Onalaja A, Claudio L (2000) Genetic Susceptibility to Lead Poisoning. Environ Health Perspect 108: 23-28.
44. Brown MJ, McWeeney G, Kim R, Tahirukaj A, Bulat P, et al. (2010) Lead poisoning among internally displaced Roma, Ashkali and Egyptian children in the United Nations-Administered Province of Kosovo. Eur J Public Health 20: 288-292.
45. Kaul B, Sandhu RS, Depratt C, Reyes F (1999) Follow-up screening of leadpoisoned children near an auto battery recycling plant, Haina, Dominican Republic. Environ Health Perspect 107:917-920.
46. van der Kuijp T, Huang L, Cherry CR (2013) Health hazards of China's leadacid battery industry: a review of its market drivers, production processes, and health impacts. Environmental Health 12:61
47. Li P, Feng XB, Qiu GL, Shang LH, Li ZG (2009) Mercury pollution in Asia: A review of the contaminated sites. J Haz Mat 168:591-601
48. Bose-O'Reilly S, McCarty KM, Steckling N, Lettmeier B (2010) Mercury exposure and children's health. Curr Probl Pediatr Adolesc Health Care. 40:186-215.
49. Uetani M, Kobayashi E, Suwazono Y, Honda R, Nishijo M, et al. (2006) Tissue cadmium (Cd) concentrations of people living in a Cd polluted area, Japan. Biometals. 19:521-5.