Safety and efficacy of succimer in toddlers with blood lead levels of 20-44 μg/dL

Pediatric Research

Volumn 48, Issue 5, 2000, Pages 593-599

  Rogan, W J ^a   Bornschein, R L ^a   Chisolm J J , Jr ^a   Damokosh, A I ^a   Dockery, D W ^a   Fay, M E ^a   Jones, R L ^a   Rhoads, G G ^a   Ragan, N B ^a   Salganik, M ^a   Schwarz, D F ^a   Ware, J H ^a   Wedeen, R P ^a   Serwint, J ^a   Brophy, M ^a   Davoli, C T ^a   Denckla, M B ^a   Farfel, M R ^a   Goldstein, G W ^a   Rubin, J ^a   Berger, O ^a   Dietrich, K N ^a   Wesolowski, C ^a   Wilkins, S ^a   Maynard Wentzel, G ^a   Mortensen, M E ^a   Adubato, S ^a   Elsafty, M ^a   Heenehan, M ^a   Sheffet, A ^a   Ty, A ^a   Campbell, C ^a   Gill, F M ^a   Guinn, J ^a   Henretig, F ^a   Knight, D ^a   Radcliffe, J ^a   Bowman, B B ^a   Gunter, E ^a   Huff, D ^a   Miller, D T ^a   Paschal, D C ^a   Bernstein, A J ^a   Kotlov, T V ^a   Angle, C R ^a   Faison, J ^a   Gehlbach, S H ^a   Gray Little, B ^a   James, S A ^a   Moye, L A ^a   Needleman, H L ^a   more..

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD; PLACEBO; SUCCIMER;

ARTICLE; CLINICAL TRIAL; COGNITIVE DEFECT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; GASTROINTESTINAL SYMPTOM; HUMAN; INJURY; LEAD BLOOD LEVEL; LEAD POISONING; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NEUROTOXICITY; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH;

EID: 0033761318     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200011000-00007     Document Type: Article

References (18)

1. Exposure of the U.S. population to lead, 1991-1994
2. Lead exposure and the cognitive development of urban preschool children: The Cincinnati lead study cohort at age 4 years
3. Port Pirie cohort study: Environmental exposure to lead and children's abilities at the age of four years
4. Low-level lead exposure and children's cognitive function in the preschool years
5. The developmental consequences of low to moderate prenatal and postnatal lead exposure: Intellectual attainment in the Cincinnati lead study cohort following school entry
6. Low-level lead exposure, intelligence and academic achievement: A long-term follow-up study
7. Succimer (DMSA) approved for severe lead poisoning
8. Dose-response study of oral 2,3-dimercaptosuccinic acid in children with elevated blood lead concentrations
9. The Treatment of Lead-exposed Children (TLC) Trial: Design and recruitment for a study of the effect of oral chelation on growth and development in toddlers
10. Recall of a lead-contaminated vitamin and mineral supplement in a clinical trial
11. Treatment of lead-exposed children
12. Locally weighted regression: An approach to regression analysis by local fitting
13. Children with moderately elevated lead levels: Is chelation with DMSA helpful?
14. Environmental lead and children's intelligence: A systematic review of the epidemiological evidence
15. Efficacy of succimer chelation for reducing brain lead in a primate model of human lead exposure