Bilayer tablet formulation of metformin HCl and acarbose: A novel approach to control diabetes

PDA Journal of Pharmaceutical Science and Technology

Volumn 68, Issue 2, 2014, Pages 138-152

  Tiwari, Ruchi ^a   Gupta, Ankita ^a   Joshi, Meenakshi ^a   Tiwari, Gaurav ^a  

^a PRANVEER SINGH INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Acarbose; Bilayer tablets; Eudragit RS 100; Metformin HCl; PEG 6000; PVP K30; RL 100; Solid dispersions

Indexed keywords

ACARBOSE; EUDRAGIT; EUDRAGIT RS; MACROGOL 6000; METFORMIN; MICROCRYSTALLINE CELLULOSE; POVIDONE; ACRYLIC ACID RESIN; ANTIDIABETIC AGENT; DRUG CARRIER; GLYCOSIDASE INHIBITOR; MACROGOL DERIVATIVE;

ARTICLE; BILAYER MEMBRANE; CONTROLLED STUDY; DIABETES CONTROL; DIABETES MELLITUS; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DISSOLUTION; DRUG EFFECT; DRUG RELEASE; EVAPORATION; HARDNESS; HUMAN; HYDROGEN BOND; IN VITRO STUDY; INFRARED SPECTROSCOPY; KINETICS; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; TABLET FORMULATION; THICKNESS; WEIGHT; X RAY DIFFRACTION; BLOOD; CHEMICAL MODEL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG COMBINATION; DRUG FORMULATION; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION; PHARMACEUTICS; PROCEDURES; SOLUBILITY; SURFACE PROPERTY; TABLET;

ACARBOSE; ACRYLIC RESINS; ADMINISTRATION, ORAL; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS; DIFFUSION; DRUG CARRIERS; DRUG COMBINATIONS; DRUG COMPOUNDING; DRUG LIBERATION; GLYCOSIDE HYDROLASE INHIBITORS; HYDROGEN BONDING; HYPOGLYCEMIC AGENTS; KINETICS; METFORMIN; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; POVIDONE; SOLUBILITY; SURFACE PROPERTIES; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84899684033     PISSN: 10797440     EISSN: 19482124     Source Type: Journal    
DOI: 10.5731/pdajpst.2014.00953     Document Type: Article

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