First Evaluation of drug-resistant mycobacterium tuberculosis clinical isolates from congo revealed misdetection of fluoroquinolone resistance by line probe assay due to a double substitution t80a-a90g in gyra

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Aubry, Alexandra ^a,b,c   Sougakoff, Wladimir ^a,b,c   Bodzongo, Pamela ^d   Delcroix, Guy ^e   Armand, Sylvie ^e   Millot, Gerald ^c   Jarlier, Vincent ^a,b,c   Courcol, Rene ^e,f,g   Lemâtre, Nadine ^e,f,g  

^a SORBONNE UNIVERSITÉ   (France)

^b INSERM   (France)

^c Microangiopathies Thrombotiques de l'Adulte et de l'Enfant (MAT)   (France)

^d Faculte des Sciences de la Sante   (Congo)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f UNIV LILLE   (France)

^g INSERM U1019   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CAPREOMYCIN; ISONIAZID; MOXIFLOXACIN; OFLOXACIN; QUINOLONE DERIVATIVE; RIFAMPICIN; STREPTOMYCIN; DNA TOPOISOMERASE (ATP HYDROLYSING);

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM ISOLATE; CODON; CONGO; DNA SEQUENCE; GENE MUTATION; GENOTYPE; GYRA GENE; HUMAN; KATG GENE; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; RPOB GENE; AMINO ACID SUBSTITUTION; CLINICAL TRIAL; EPIDEMIOLOGY; FEMALE; GENETICS; ISOLATION AND PURIFICATION; MALE; NUCLEOTIDE SEQUENCE; TUBERCULOSIS;

AMINO ACID SUBSTITUTION; CONGO; DNA GYRASE; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, BACTERIAL; FEMALE; FLUOROQUINOLONES; HUMANS; MALE; MUTATION, MISSENSE; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

EID: 84899681851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095083     Document Type: Article

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