Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wu, Tingting ^a   Shi, Zheng ^a   Baumgart, Tobias ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARAGINE; ASPARTIC ACID; GLUTAMINE; LIPOSOME; MEMBRANE PROTEIN; MUTANT PROTEIN; PROTEIN BIN1; UNCLASSIFIED DRUG; ACTIN; BIN1 PROTEIN, HUMAN; CROSS LINKING REAGENT; NUCLEAR PROTEIN; RECOMBINANT PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CENTRONUCLEAR MYOPATHY; CONTROLLED STUDY; CROSS LINKING; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MEMBRANE BINDING; MEMBRANE DAMAGE; MEMBRANE STRUCTURE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; OLIGOMERIZATION; PATHOPHYSIOLOGY; PROTEIN BINDING; ANIMAL; CHEMISTRY; FLUORESCENCE MICROSCOPY; GENETICS; HUMAN; METABOLISM; MYOPATHY; PATHOLOGY; POINT MUTATION; POLYMERIZATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL MEMBRANE; CROSS-LINKING REAGENTS; HUMANS; LIPOSOMES; MICE; MICROSCOPY, FLUORESCENCE; MUTANT PROTEINS; MYOPATHIES, STRUCTURAL, CONGENITAL; NUCLEAR PROTEINS; POINT MUTATION; POLYMERIZATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TUMOR SUPPRESSOR PROTEINS;

EID: 84899676580     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093060     Document Type: Article

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