Arsenic trioxide induces apoptosis in human platelets via C-Jun NH 2-terminal kinase activation

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Wu, Yicun ^a   Dai, Jin ^b   Zhang, Weilin ^a   Yan, Rong ^a   Zhang, Yiwen ^a   Ruan, Changgeng ^a   Dai, Kesheng ^a  

^a SOOCHOW UNIVERSITY   (China)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ARSENIC TRIOXIDE; CASPASE 3; DUAL SPECIFICITY PHOSPHATASE 2; JANUS KINASE 2; JANUS KINASE 3; PADGEM PROTEIN; PHOSPHATIDYLSERINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOCYTOPENIA; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOOD PLATELETS; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FEMALE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; OXIDES; PLATELET ACTIVATION; PLATELET COUNT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84899656966     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086445     Document Type: Article

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