메뉴 건너뛰기




Volumn 111, Issue 17, 2014, Pages 6437-6442

Avirulent strains of Toxoplasma gondii infect macrophages by active invasion from the phagosome

Author keywords

Apicomplexa; Phagocytes; Trojan horse; Virulence

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1;

EID: 84899650244     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1316841111     Document Type: Article
Times cited : (32)

References (42)
  • 1
    • 84867648270 scopus 로고    scopus 로고
    • Subversion of phagocytosis for pathogen survival
    • Sarantis H, Grinstein S (2012) Subversion of phagocytosis for pathogen survival. Cell Host Microbe 12(4):419-431.
    • (2012) Cell Host Microbe , vol.12 , Issue.4 , pp. 419-431
    • Sarantis, H.1    Grinstein, S.2
  • 2
    • 0033397899 scopus 로고    scopus 로고
    • Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring
    • Mordue DG, Desai N, Dustin M, Sibley LD (1999) Invasion by Toxoplasma gondii establishes a moving junction that selectively excludes host cell plasma membrane proteins on the basis of their membrane anchoring. J Exp Med 190(12):1783-1792.
    • (1999) J Exp Med , vol.190 , Issue.12 , pp. 1783-1792
    • Mordue, D.G.1    Desai, N.2    Dustin, M.3    Sibley, L.D.4
  • 3
    • 0029869791 scopus 로고    scopus 로고
    • Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite
    • Dobrowolski JM, Sibley LD (1996) Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite. Cell 84(6):933-939.
    • (1996) Cell , vol.84 , Issue.6 , pp. 933-939
    • Dobrowolski, J.M.1    Sibley, L.D.2
  • 4
    • 0025160102 scopus 로고
    • Toxoplasma gondii: Fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts
    • Joiner KA, Fuhrman SA, Miettinen HM, Kasper LH, Mellman I (1990) Toxoplasma gondii: Fusion competence of parasitophorous vacuoles in Fc receptor-transfected fibroblasts. Science 249(4969):641-646.
    • (1990) Science , vol.249 , Issue.4969 , pp. 641-646
    • Joiner, K.A.1    Fuhrman, S.A.2    Miettinen, H.M.3    Kasper, L.H.4    Mellman, I.5
  • 5
    • 0345151828 scopus 로고    scopus 로고
    • Toxoplasma gondii resides in a vacuole that avoids fusion with host cell endocytic and exocytic vesicular trafficking pathways
    • Mordue DG, Hakansson S, Niesman I, Sibley LD (1999) Toxoplasma gondii resides in a vacuole that avoids fusion with host cell endocytic and exocytic vesicular trafficking pathways. Exp Parasitol 92(2):87-99.
    • (1999) Exp Parasitol , vol.92 , Issue.2 , pp. 87-99
    • Mordue, D.G.1    Hakansson, S.2    Niesman, I.3    Sibley, L.D.4
  • 6
    • 0021827581 scopus 로고
    • Phagosome acidification blocked by intracellular Toxoplasma gondii
    • Sibley LD, Weidner E, Krahenbuhl JL (1985) Phagosome acidification blocked by intracellular Toxoplasma gondii. Nature 315(6018):416-419.
    • (1985) Nature , vol.315 , Issue.6018 , pp. 416-419
    • Sibley, L.D.1    Weidner, E.2    Krahenbuhl, J.L.3
  • 7
    • 61849132162 scopus 로고    scopus 로고
    • Host cell entry by apicomplexa parasites requires actin polymerization in the host cell
    • Gonzalez V, et al. (2009) Host cell entry by apicomplexa parasites requires actin polymerization in the host cell. Cell Host Microbe 5(3):259-272.
    • (2009) Cell Host Microbe , vol.5 , Issue.3 , pp. 259-272
    • Gonzalez, V.1
  • 8
    • 84873406471 scopus 로고    scopus 로고
    • Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms
    • Andenmatten N, et al. (2013) Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms. Nat Methods 10(2):125-127.
    • (2013) Nat Methods , vol.10 , Issue.2 , pp. 125-127
    • Andenmatten, N.1
  • 9
    • 1542619259 scopus 로고    scopus 로고
    • Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype
    • Robben PM, et al. (2004) Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype. J Immunol 172(6):3686-3694.
    • (2004) J Immunol , vol.172 , Issue.6 , pp. 3686-3694
    • Robben, P.M.1
  • 10
    • 63149149461 scopus 로고    scopus 로고
    • The Toxoplasma gondiishuttling function of dendritic cells is linked to the parasite genotype
    • Lambert H, Vutova PP, Adams WC, Loré K, Barragan A (2009) The Toxoplasma gondiishuttling function of dendritic cells is linked to the parasite genotype. Infect Immun 77(4):1679-1688.
    • (2009) Infect Immun , vol.77 , Issue.4 , pp. 1679-1688
    • Lambert, H.1    Vutova, P.P.2    Adams, W.C.3    Loré, K.4    Barragan, A.5
  • 11
    • 30144432329 scopus 로고    scopus 로고
    • CD11c-and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain
    • Courret N, et al. (2006) CD11c-and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain. Blood 107(1):309-316.
    • (2006) Blood , vol.107 , Issue.1 , pp. 309-316
    • Courret, N.1
  • 12
    • 33748469339 scopus 로고    scopus 로고
    • Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination
    • Lambert H, Hitziger N, Dellacasa I, Svensson M, Barragan A (2006) Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination. Cell Microbiol 8(10):1611-1623.
    • (2006) Cell Microbiol , vol.8 , Issue.10 , pp. 1611-1623
    • Lambert, H.1    Hitziger, N.2    Dellacasa, I.3    Svensson, M.4    Barragan, A.5
  • 13
    • 0029016818 scopus 로고
    • Invasion of Toxoplasma gondii occurs by active penetration of the host cell
    • Morisaki JH, Heuser JE, Sibley LD (1995) Invasion of Toxoplasma gondii occurs by active penetration of the host cell. J Cell Sci 108(Pt 6):2457-2464.
    • (1995) J Cell Sci , vol.108 , Issue.PART 6 , pp. 2457-2464
    • Morisaki, J.H.1    Heuser, J.E.2    Sibley, L.D.3
  • 14
    • 0029927089 scopus 로고    scopus 로고
    • The effects of inhibitors of vacuolar acidification on the release of Listeria monocytogenes from phagosomes of Caco-2 cells
    • Conte MP, et al. (1996) The effects of inhibitors of vacuolar acidification on the release of Listeria monocytogenes from phagosomes of Caco-2 cells. J Med Microbiol 44(6):418-424.
    • (1996) J Med Microbiol , vol.44 , Issue.6 , pp. 418-424
    • Conte, M.P.1
  • 15
    • 46249110662 scopus 로고    scopus 로고
    • Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol
    • Santic M, Asare R, Skrobonja I, Jones S, Abu Kwaik Y (2008) Acquisition of the vacuolar ATPase proton pump and phagosome acidification are essential for escape of Francisella tularensis into the macrophage cytosol. Infect Immun 76(6):2671-2677.
    • (2008) Infect Immun , vol.76 , Issue.6 , pp. 2671-2677
    • Santic, M.1    Asare, R.2    Skrobonja, I.3    Jones, S.4    Abu Kwaik, Y.5
  • 16
    • 65449163019 scopus 로고    scopus 로고
    • Virulent Toxoplasma gondii evade immunity-related GTPasemediated parasite vacuole disruption within primed macrophages
    • Zhao Y, et al. (2009) Virulent Toxoplasma gondii evade immunity-related GTPasemediated parasite vacuole disruption within primed macrophages. J Immunol 182(6): 3775-3781.
    • (2009) J Immunol , vol.182 , Issue.6 , pp. 3775-3781
    • Zhao, Y.1
  • 17
    • 49649126253 scopus 로고    scopus 로고
    • Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases
    • Martens S, et al. (2005) Disruption of Toxoplasma gondii parasitophorous vacuoles by the mouse p47-resistance GTPases. PLoS Pathog 1(3):e24.
    • (2005) PLoS Pathog , vol.1 , Issue.3
    • Martens, S.1
  • 18
    • 85066453812 scopus 로고    scopus 로고
    • Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages
    • Ling YM, et al. (2006) Vacuolar and plasma membrane stripping and autophagic elimination of Toxoplasma gondii in primed effector macrophages. J Exp Med 203(9): 2063-2071.
    • (2006) J Exp Med , vol.203 , Issue.9 , pp. 2063-2071
    • Ling, Y.M.1
  • 19
    • 0028886480 scopus 로고
    • Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease
    • Howe DK, Sibley LD (1995) Toxoplasma gondii comprises three clonal lineages: Correlation of parasite genotype with human disease. J Infect Dis 172(6):1561-1566.
    • (1995) J Infect Dis , vol.172 , Issue.6 , pp. 1561-1566
    • Howe, D.K.1    Sibley, L.D.2
  • 20
    • 0026706230 scopus 로고
    • Virulent strains of Toxoplasma gondii comprise a single clonal lineage
    • Sibley LD, Boothroyd JC (1992) Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 359(6390):82-85.
    • (1992) Nature , vol.359 , Issue.6390 , pp. 82-85
    • Sibley, L.D.1    Boothroyd, J.C.2
  • 21
    • 79952123931 scopus 로고    scopus 로고
    • Microbial manipulation of receptor crosstalk in innate immunity
    • Hajishengallis G, Lambris JD (2011) Microbial manipulation of receptor crosstalk in innate immunity. Nat Rev Immunol 11(3):187-200.
    • (2011) Nat Rev Immunol , vol.11 , Issue.3 , pp. 187-200
    • Hajishengallis, G.1    Lambris, J.D.2
  • 22
    • 84886041693 scopus 로고    scopus 로고
    • Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin
    • Raetz M, et al. (2013) Cooperation of TLR12 and TLR11 in the IRF8-dependent IL-12 response to Toxoplasma gondii profilin. J Immunol 191(9):4818-4827.
    • (2013) J Immunol , vol.191 , Issue.9 , pp. 4818-4827
    • Raetz, M.1
  • 23
    • 79952789527 scopus 로고    scopus 로고
    • UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii
    • Pifer R, Benson A, Sturge CR, Yarovinsky F (2011) UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii. J Biol Chem 286(5):3307-3314.
    • (2011) J Biol Chem , vol.286 , Issue.5 , pp. 3307-3314
    • Pifer, R.1    Benson, A.2    Sturge, C.R.3    Yarovinsky, F.4
  • 24
    • 84872596639 scopus 로고    scopus 로고
    • Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice
    • Andrade WA, et al. (2013) Combined action of nucleic acid-sensing Toll-like receptors and TLR11/TLR12 heterodimers imparts resistance to Toxoplasma gondii in mice. Cell Host Microbe 13(1):42-53.
    • (2013) Cell Host Microbe , vol.13 , Issue.1 , pp. 42-53
    • Andrade, W.A.1
  • 25
    • 84890831999 scopus 로고    scopus 로고
    • NLRP1 is an inflammasome sensor for Toxoplasma gondii
    • Ewald SE, Chavarria-Smith J, Boothroyd JC (2014) NLRP1 is an inflammasome sensor for Toxoplasma gondii. Infect Immun 82(1):460-468.
    • (2014) Infect Immun , vol.82 , Issue.1 , pp. 460-468
    • Ewald, S.E.1    Chavarria-Smith, J.2    Boothroyd, J.C.3
  • 26
    • 79251522140 scopus 로고    scopus 로고
    • NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondiiinfected monocytic cells
    • Witola WH, et al. (2011) NALP1 influences susceptibility to human congenital toxoplasmosis, proinflammatory cytokine response, and fate of Toxoplasma gondiiinfected monocytic cells. Infect Immun 79(2):756-766.
    • (2011) Infect Immun , vol.79 , Issue.2 , pp. 756-766
    • Witola, W.H.1
  • 27
    • 78651504365 scopus 로고    scopus 로고
    • Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein
    • Rosowski EE, et al. (2011) Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein. J Exp Med 208(1):195-212.
    • (2011) J Exp Med , vol.208 , Issue.1 , pp. 195-212
    • Rosowski, E.E.1
  • 28
    • 84883444752 scopus 로고    scopus 로고
    • Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15
    • Gov L, Karimzadeh A, Ueno N, Lodoen MB (2013) Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15. MBio 4(4): e00255-13.
    • (2013) MBio , vol.4 , Issue.4
    • Gov, L.1    Karimzadeh, A.2    Ueno, N.3    Lodoen, M.B.4
  • 29
    • 84876332081 scopus 로고    scopus 로고
    • Toxoplasma gondii tachyzoite-infected peripheral blood mononuclear cells are enriched in mouse lungs and liver
    • Unno A, et al. (2013) Toxoplasma gondii tachyzoite-infected peripheral blood mononuclear cells are enriched in mouse lungs and liver. Exp Parasitol 134(2):160-164.
    • (2013) Exp Parasitol , vol.134 , Issue.2 , pp. 160-164
    • Unno, A.1
  • 30
    • 0033943813 scopus 로고    scopus 로고
    • Differential infectivity and division of Toxoplasma gondii in human peripheral blood leukocytes
    • Channon JY, Seguin RM, Kasper LH (2000) Differential infectivity and division of Toxoplasma gondii in human peripheral blood leukocytes. Infect Immun 68(8): 4822-4826.
    • (2000) Infect Immun , vol.68 , Issue.8 , pp. 4822-4826
    • Channon, J.Y.1    Seguin, R.M.2    Kasper, L.H.3
  • 31
    • 84878116280 scopus 로고    scopus 로고
    • Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread
    • Coombes JL, et al. (2013) Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread. Proc Natl Acad Sci USA 110(21):E1913-E1922.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.21
    • Coombes, J.L.1
  • 32
    • 78650590967 scopus 로고    scopus 로고
    • Migratory responses of leukocytes infected with Toxoplasma gondii
    • Lambert H, Dellacasa-Lindberg I, Barragan A (2011) Migratory responses of leukocytes infected with Toxoplasma gondii. Microbes Infect 13(1):96-102.
    • (2011) Microbes Infect , vol.13 , Issue.1 , pp. 96-102
    • Lambert, H.1    Dellacasa-Lindberg, I.2    Barragan, A.3
  • 33
    • 79954889434 scopus 로고    scopus 로고
    • Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America
    • Khan A, et al. (2011) Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America. Int J Parasitol 41(6):645-655.
    • (2011) Int J Parasitol , vol.41 , Issue.6 , pp. 645-655
    • Khan, A.1
  • 34
    • 65649111678 scopus 로고    scopus 로고
    • Genotype of 88 Toxoplasma gondii isolates associated with toxoplasmosis in immunocompromised patients and correlation with clinical findings
    • Ajzenberg D, et al. (2009) Genotype of 88 Toxoplasma gondii isolates associated with toxoplasmosis in immunocompromised patients and correlation with clinical findings. J Infect Dis 199(8):1155-1167.
    • (2009) J Infect Dis , vol.199 , Issue.8 , pp. 1155-1167
    • Ajzenberg, D.1
  • 35
    • 40949138906 scopus 로고    scopus 로고
    • Endemic toxoplasmosis in pigs on a farm in Maryland: Isolation and genetic characterization of Toxoplasma gondii
    • Dubey JP, et al. (2008) Endemic toxoplasmosis in pigs on a farm in Maryland: Isolation and genetic characterization of Toxoplasma gondii. J Parasitol 94(1):36-41.
    • (2008) J Parasitol , vol.94 , Issue.1 , pp. 36-41
    • Dubey, J.P.1
  • 36
    • 43849113435 scopus 로고    scopus 로고
    • High prevalence and abundant atypical genotypes of Toxoplasma gondii isolated from lambs destined for human consumption in the USA
    • Dubey JP, et al. (2008) High prevalence and abundant atypical genotypes of Toxoplasma gondii isolated from lambs destined for human consumption in the USA. Int J Parasitol 38(8-9):999-1006.
    • (2008) Int J Parasitol , vol.38 , Issue.8-9 , pp. 999-1006
    • Dubey, J.P.1
  • 37
    • 84892412944 scopus 로고    scopus 로고
    • Serotyping of Toxoplasma gondii in cats (Felis domesticus) reveals predominance of type II infections in Germany
    • Maksimov P, et al. (2013) Serotyping of Toxoplasma gondii in cats (Felis domesticus) reveals predominance of type II infections in Germany. PLoS ONE 8(11):e80213.
    • (2013) PLoS ONE , vol.8 , Issue.11
    • Maksimov, P.1
  • 38
    • 0347091255 scopus 로고    scopus 로고
    • Recent expansion of Toxoplasma through enhanced oral transmission
    • Su C, et al. (2003) Recent expansion of Toxoplasma through enhanced oral transmission. Science 299(5605):414-416.
    • (2003) Science , vol.299 , Issue.5605 , pp. 414-416
    • Su, C.1
  • 39
    • 33745913320 scopus 로고    scopus 로고
    • Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii
    • Boyle JP, et al. (2006) Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii. Proc Natl Acad Sci USA 103(27):10514-10519.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.27 , pp. 10514-10519
    • Boyle, J.P.1
  • 40
    • 84855226755 scopus 로고    scopus 로고
    • A monomorphic haplotype of chromosome Ia is associated with widespread success in clonal and nonclonal populations of Toxoplasma gondii
    • Khan A, et al. (2011) A monomorphic haplotype of chromosome Ia is associated with widespread success in clonal and nonclonal populations of Toxoplasma gondii. mBio 2(6):e00228-00211.
    • (2011) MBio , vol.2 , Issue.6
    • Khan, A.1
  • 41
    • 84867751254 scopus 로고    scopus 로고
    • Modulation of innate immunity by Toxoplasma gondii virulence effectors
    • Hunter CA, Sibley LD (2012) Modulation of innate immunity by Toxoplasma gondii virulence effectors. Nat Rev Microbiol 10(11):766-778.
    • (2012) Nat Rev Microbiol , vol.10 , Issue.11 , pp. 766-778
    • Hunter, C.A.1    Sibley, L.D.2
  • 42
    • 0037148779 scopus 로고    scopus 로고
    • De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii
    • Fox BA, Bzik DJ (2002) De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii. Nature 415(6874):926-929.
    • (2002) Nature , vol.415 , Issue.6874 , pp. 926-929
    • Fox, B.A.1    Bzik, D.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.